Gene Information gene info

GENE:CPT1A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CPT1A
FullNmae carnitine palmitoyltransferase 1A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2328
EnsembleID ENSG00000110090
Uniprot P50416

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CPT1A ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CPT1A autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CPT1A GO:0001676,GO:0004095,GO:0004095,GO:0004095,GO:0004095,GO:0005739,GO:0005739,GO:0005741,GO:0005741,GO:0005741,GO:0006006,GO:0006631,GO:0006635,GO:0006641,GO:0006853,GO:0009410,GO:0009437,GO:0009437,GO:0010883,GO:0014070,GO:0016020,GO:0030855,GO:0031667,GO:0032000,GO:0042755,GO:0042802,GO:0043279,GO:0045471,GO:0050796,GO:0071398,GO:0097421,GO:1904772,GO:1990698

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CPT1A hsa:1374 path:hsa00071 Fatty acid degradation - Homo sapiens (human)
CPT1A hsa:1374 path:hsa01212 Fatty acid metabolism - Homo sapiens (human)
CPT1A hsa:1374 path:hsa03320 PPAR signaling pathway - Homo sapiens (human)
CPT1A hsa:1374 path:hsa04148 Efferocytosis - Homo sapiens (human)
CPT1A hsa:1374 path:hsa04152 AMPK signaling pathway - Homo sapiens (human)
CPT1A hsa:1374 path:hsa04714 Thermogenesis - Homo sapiens (human)
CPT1A hsa:1374 path:hsa04920 Adipocytokine signaling pathway - Homo sapiens (human)
CPT1A hsa:1374 path:hsa04922 Glucagon signaling pathway - Homo sapiens (human)
CPT1A hsa:1374 path:hsa04931 Insulin resistance - Homo sapiens (human)
CPT1A hsa:1374 path:hsa04936 Alcoholic liver disease - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RNF2 CPT1A 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 CPT1A 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 CPT1A 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 CPT1A 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 CPT1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CPT1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CPT1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CPT1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CPT1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 CPT1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CPT1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CPT1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF CPT1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 CPT1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PPARA CPT1A 17150915 trascriptional regulation,stimulation inferred by curator TFlink
AR CPT1A N/A trascriptional regulation,stimulation inferred by curator TFlink
CREB1 CPT1A N/A trascriptional regulation,stimulation inferred by curator TFlink
E2F1 CPT1A N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00004900F1 CPT1A 20124555 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00004900F1 CPT1A 20124555 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000338542 CPT1A 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000F4AC3 CPT1A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000018D2BE CPT1A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000277201 CPT1A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB14 CPT1A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1A CPT1A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001AFC71 CPT1A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 CPT1A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000021D08 CPT1A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 CPT1A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 CPT1A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 CPT1A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F CPT1A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA CPT1A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 CPT1A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 CPT1A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 CPT1A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 CPT1A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C CPT1A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 CPT1A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 CPT1A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000078918 CPT1A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000EE7F0 CPT1A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003B59DF CPT1A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000E1E9E CPT1A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003FA24D CPT1A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075B538 CPT1A 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E CPT1A 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000160683 CPT1A 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000017DBB8 CPT1A 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000CBE63 CPT1A 25416803 27199118 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
CPT1A BCL2 25361965 interaction type N/A PTMCode2
BCL2 CPT1A 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
ERLIN1 CPT1A 25348397 N/A physical interaction ComPPI
PCBP1 CPT1A 25348397 N/A physical interaction ComPPI
NPDC1 CPT1A 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
KBTBD7 CPT1A 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
NDUFAF4 CPT1A 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
LYN CPT1A 25348397 N/A physical interaction ComPPI
RHOA CPT1A 25348397 N/A physical interaction ComPPI
RAB7A CPT1A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TUBG1 CPT1A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBC CPT1A 25348397 N/A physical interaction ComPPI
NTRK1 CPT1A 25348397 N/A physical interaction ComPPI
ENO1 CPT1A 25348397 N/A physical interaction ComPPI
HSPA5 CPT1A 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CACYBP CPT1A 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
HNRNPL CPT1A 25348397 N/A physical interaction ComPPI
GABRG2 CPT1A 25348397 N/A physical interaction ComPPI
EIF3C CPT1A 25348397 N/A physical interaction ComPPI
PDHA1 CPT1A 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
HUWE1 CPT1A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NR4A1 CPT1A 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RNF2 CPT1A 25348397 N/A physical interaction ComPPI
HDAC6 CPT1A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CYBA CPT1A 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
BCL2 CPT1A 14525934 25348397 27898060 9070836 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
PRKN CPT1A 25348397 N/A physical interaction ComPPI
CLIC1 CPT1A 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
LPP CPT1A 25348397 N/A physical interaction ComPPI
HDAC11 CPT1A 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRIM25 CPT1A 25348397 N/A physical interaction ComPPI
ESR2 CPT1A 21182203 24234451 25348397 association affinity chromatography technology,cosedimentation through density gradient ComPPI,IntAct
SNRNP200 CPT1A 25348397 N/A physical interaction ComPPI
TOMM40 CPT1A 25348397 N/A physical interaction ComPPI
CPT1A CLN3 25348397 N/A physical interaction ComPPI
CPT1A PCK1 25348397 N/A physical interaction ComPPI
CPT1A CPS1 25348397 N/A physical interaction ComPPI
CPT1A NDUFA2 25348397 N/A physical interaction ComPPI
CPT1A NDUFV1 25348397 N/A physical interaction ComPPI
CPT1A NDUFS1 25348397 N/A physical interaction ComPPI
CPT1A FBXO6 25348397 N/A physical interaction ComPPI
CPT1A LGR4 25348397 N/A physical interaction ComPPI
CPT1A MOV10 25348397 N/A physical interaction ComPPI
CPT1A NXF1 25348397 N/A physical interaction ComPPI
CPT1A HERC2 25348397 N/A physical interaction ComPPI
CPT1A HERC2P3 25348397 N/A physical interaction ComPPI
CPT1A COQ9 25348397 N/A physical interaction ComPPI
CPT1A NDUFA4 25348397 N/A physical interaction ComPPI
CPT1A TBC1D9 25348397 N/A physical interaction ComPPI
CPT1A SDHA 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
CPT1A E2F3 22157815 24234451 25348397 association pull down ComPPI,IntAct
CPT1A COX6B1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
ATP6V1C1 CPT1A 25348397 N/A physical interaction ComPPI

Visualization