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GENE：DCTPP1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DCTPP1
FullNmae dCTP pyrophosphatase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:28777
EnsembleID ENSG00000179958
Uniprot Q9H773

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DCTPP1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DCTPP1 GO:0000287,GO:0005515,GO:0005634,GO:0005654,GO:0005739,GO:0005829,GO:0005829,GO:0005829,GO:0006253,GO:0006253,GO:0009143,GO:0009143,GO:0032556,GO:0042262,GO:0042262,GO:0042802,GO:0047429,GO:0047429,GO:0047840,GO:0047840

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
DCTPP1 hsa:79077 path:hsa00240 Pyrimidine metabolism - Homo sapiens (human)
DCTPP1 hsa:79077 path:hsa01100 Metabolic pathways - Homo sapiens (human)
DCTPP1 hsa:79077 path:hsa01232 Nucleotide metabolism - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ESR1 DCTPP1 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 DCTPP1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 DCTPP1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 DCTPP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA DCTPP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DCTPP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS DCTPP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A DCTPP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 DCTPP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000324096 DCTPP1 18668040 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,experimental interaction detection TarBase
URS00000EED18 DCTPP1 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000003ABC4 DCTPP1 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00003D5391 DCTPP1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000600E6 DCTPP1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002075FA DCTPP1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005D986D DCTPP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000284586 DCTPP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000058BB84 DCTPP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075D1FC DCTPP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 DCTPP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE DCTPP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D DCTPP1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000480E22 DCTPP1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000043B1D DCTPP1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000B1B47 DCTPP1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000025307A DCTPP1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000328C0D DCTPP1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000451A1 DCTPP1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000005CE28 DCTPP1 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CUL5 DCTPP1 25348397 N/A physical interaction ComPPI
PCNA DCTPP1 25348397 N/A physical interaction ComPPI
DCTPP1 NTAQ1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
DCTPP1 PLK1 19596235 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DCTPP1 NEDD8 25348397 N/A physical interaction ComPPI
DCTPP1 APP 25348397 N/A physical interaction ComPPI
DCTPP1 CAPZB 25348397 N/A physical interaction ComPPI
DCTPP1 CTPS1 25348397 N/A physical interaction ComPPI
DCTPP1 UBQLN1 25348397 N/A physical interaction ComPPI
DCTPP1 RAD23A 25348397 N/A physical interaction ComPPI
DCTPP1 WDR4 25348397 N/A physical interaction ComPPI
DCTPP1 WWOX 25348397 N/A physical interaction ComPPI
DCTPP1 SDCBP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
DCTPP1 NXF1 25348397 N/A physical interaction ComPPI
DCTPP1 CRY2 25348397 N/A physical interaction ComPPI
DCTPP1 EYA4 25348397 N/A physical interaction ComPPI
DCTPP1 DUSP26 25348397 N/A physical interaction ComPPI
DCTPP1 DLD 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
DCTPP1 VHL 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DCTPP1 HLA-B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DCTPP1 LNX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DCTPP1 SPG21 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DCTPP1 PSMA1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct

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