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GENE：EFNB1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EFNB1
FullNmae ephrin B1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3226
EnsembleID ENSG00000090776
Uniprot P98172

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EFNB1 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
EFNB1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
EFNB1 GO:0001755,GO:0005515,GO:0005634,GO:0005737,GO:0005886,GO:0005886,GO:0005886,GO:0007155,GO:0007267,GO:0007411,GO:0009880,GO:0009986,GO:0031295,GO:0042098,GO:0042102,GO:0045121,GO:0045202,GO:0046875,GO:0046875,GO:0048013,GO:0070062,GO:2000785

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
EFNB1 hsa:1947 path:hsa04360 Axon guidance - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EFNB1 EPHB1 23331499 9267020 stimulation N/A SignaLink
EFNB1 EPHB2 23331499 9576626 stimulation N/A SignaLink
EFNB1 EPHB3 23331499 9576626 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 EFNB1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 EFNB1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 EFNB1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 EFNB1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 EFNB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA EFNB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF EFNB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 EFNB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 EFNB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS EFNB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A EFNB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 EFNB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR EFNB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EED18 EFNB1 21566225 23592263 25416803 mrna cleavage,inhibition experimental interaction detection,clip TarBase
URS00001A7F58 EFNB1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002152A8 EFNB1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000105D19 EFNB1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002971AB EFNB1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001B968D EFNB1 23592263 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00000393C7 EFNB1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001C85C7 EFNB1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000237E04 EFNB1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003758F0 EFNB1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001F5B39 EFNB1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002C7B2B EFNB1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 EFNB1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075D1FC EFNB1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002198F3 EFNB1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000027352D EFNB1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000366551 EFNB1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D EFNB1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002AA55A EFNB1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002004E0 EFNB1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000001EB3 EFNB1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000419B5A EFNB1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000010BD8D EFNB1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001919B0 EFNB1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005ACA7C EFNB1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00000ECE9C EFNB1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00001CF056 EFNB1 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
EFNB1 NCK2 25361965 interaction type N/A PTMCode2
NCK2 EFNB1 25361965 interaction type N/A PTMCode2
EFNB1 EFNB2 25361965 interaction type N/A PTMCode2
EFNB2 EFNB1 25361965 interaction type N/A PTMCode2
EFNB1 RGS3 25361965 interaction type N/A PTMCode2
RGS3 EFNB1 25361965 interaction type N/A PTMCode2
EFNB1 SDCBP 25361965 interaction type N/A PTMCode2
SDCBP EFNB1 25361965 interaction type N/A PTMCode2
EFNB1 TIAM1 25361965 interaction type N/A PTMCode2
TIAM1 EFNB1 25361965 interaction type N/A PTMCode2
EFNB1 NCK1 25361965 interaction type N/A PTMCode2
NCK1 EFNB1 25361965 interaction type N/A PTMCode2
EFNB1 EPHA3 25361965 interaction type N/A PTMCode2
EPHA3 EFNB1 25361965 interaction type N/A PTMCode2
EFNB1 SRC 25361965 interaction type N/A PTMCode2
SRC EFNB1 25361965 interaction type N/A PTMCode2
EFNB1 EPHB2 25361965 interaction type N/A PTMCode2
EPHB2 EFNB1 25361965 interaction type N/A PTMCode2
EFNB1 EPHB6 25361965 interaction type N/A PTMCode2
EPHB6 EFNB1 25361965 interaction type N/A PTMCode2
EFNB1 EPHB1 25361965 interaction type N/A PTMCode2
EPHB1 EFNB1 25361965 interaction type N/A PTMCode2
EFNB1 GRIP1 25361965 interaction type N/A PTMCode2
GRIP1 EFNB1 25361965 interaction type N/A PTMCode2
EPHA8 EFNB1 25361965 interaction type N/A PTMCode2
EFNB1 EPHA8 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
NCK2 EFNB1 11557983 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
ERBB2 EFNB1 22279592 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,confocal microscopy ComPPI,IntAct
SMURF2 EFNB1 25348397 N/A physical interaction ComPPI
PICK1 EFNB1 14525934 25348397 9883737 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
TIAM1 EFNB1 14525934 14988728 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
SRC EFNB1 14525934 25348397 8878483 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
EPHB2 EFNB1 14525934 25348397 8878483 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
SORBS1 EFNB1 11557983 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CUL3 EFNB1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PVR EFNB1 25348397 N/A physical interaction ComPPI
MYC EFNB1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SDCBP EFNB1 14525934 25348397 9920925 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
EPHA3 EFNB1 25348397 N/A physical interaction ComPPI
EFNB2 EFNB1 25348397 N/A physical interaction ComPPI
YWHAQ EFNB1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
EGFR EFNB1 15657067 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
EPHB1 EFNB1 10669731 12223469 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
EFNB1 PTPN13 14525934 25348397 9920925 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
EFNB1 RGS3 11301003 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
EFNB1 GRIP1 10197531 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
EFNB1 SMURF1 25348397 N/A physical interaction ComPPI
EFNB1 CAPN10 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
EFNB1 CCDC8 25348397 N/A physical interaction ComPPI
EFNB1 HLA-DQA1 25348397 N/A physical interaction ComPPI
EFNB1 HLA-DPA1 25348397 N/A physical interaction ComPPI
EFNB1 TSPAN5 25348397 N/A physical interaction ComPPI
EFNB1 ATP1B3 25348397 N/A physical interaction ComPPI
EFNB1 CEACAM21 25348397 N/A physical interaction ComPPI
EFNB1 ERGIC1 25348397 N/A physical interaction ComPPI
EFNB1 SLC39A4 25348397 N/A physical interaction ComPPI
EFNB1 WDFY2 25348397 N/A physical interaction ComPPI
EFNB1 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
EFNB1 TMEM216 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
EFNB1 PCDH12 25348397 N/A physical interaction ComPPI
EFNB1 ZDHHC11 25348397 N/A physical interaction ComPPI
EFNB1 TNFSF8 25348397 N/A physical interaction ComPPI
EFNB1 SLC39A5 25348397 N/A physical interaction ComPPI
EFNB1 C16ORF54 25348397 N/A physical interaction ComPPI
EFNB1 TMEM213 25348397 N/A physical interaction ComPPI
EFNB1 CDHR5 25348397 N/A physical interaction ComPPI
EFNB1 TGOLN2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
EFNB1 EFNB1 10197531 14525934 9883737 N/A experimental interaction detection,two hybrid HPRD
EFNB1 DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
PTPN13 EFNB1 27898060 9920925 stimulant N/A OmniPath
EFNB1 EPHB2 27898060 8878483 9330863 N/A N/A OmniPath
MAPK3 EFNB1 11466320 27898060 N/A N/A OmniPath
EFNB1 ERBB2 22279592 27898060 N/A N/A OmniPath
EFNB1 EPHB1 10669731 11713248 12223469 27898060 stimulant N/A OmniPath
EPHB6 EFNB1 15114347 27898060 N/A N/A OmniPath
EFNB1 EPHB6 11713248 27898060 stimulant N/A OmniPath
EFNB1 EPHB3 27898060 9330863 stimulant N/A OmniPath
EFNB1 EPHB4 27898060 9330863 stimulant N/A OmniPath

Visualization










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