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GENE：EIF3A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EIF3A
FullNmae eukaryotic translation initiation factor 3 subunit A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3271
EnsembleID ENSG00000107581
Uniprot Q14152

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EIF3A immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
EIF3A autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
EIF3A GO:0001732,GO:0001732,GO:0001732,GO:0002188,GO:0003723,GO:0003723,GO:0003729,GO:0003743,GO:0003743,GO:0003743,GO:0005198,GO:0005515,GO:0005654,GO:0005730,GO:0005737,GO:0005829,GO:0005829,GO:0005852,GO:0005852,GO:0005874,GO:0006413,GO:0014069,GO:0016020,GO:0016282,GO:0030971,GO:0033290,GO:0043614,GO:0070373,GO:0071540,GO:0071541,GO:0075522,GO:0075525

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EIF3D EIF3A 18628297 23180781 physical association anti tag coimmunoprecipitation InnateDB
RNF2 EIF3A 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 EIF3A 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 EIF3A 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 EIF3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA EIF3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF EIF3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 EIF3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 EIF3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 EIF3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 EIF3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A EIF3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF EIF3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 EIF3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F2 EIF3A N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 EIF3A 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00001A7F58 EIF3A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000035CC3E EIF3A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE EIF3A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000031E12 EIF3A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001BCAC5 EIF3A 25416803 28074905 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
EIF3F EIF3A 25361965 interaction type N/A PTMCode2
EIF3A EIF3F 25361965 interaction type N/A PTMCode2
ABCE1 EIF3A 25361965 interaction type N/A PTMCode2
EIF3A ABCE1 25361965 interaction type N/A PTMCode2
EIF3J EIF3A 25361965 interaction type N/A PTMCode2
EIF3A EIF3J 25361965 interaction type N/A PTMCode2
WDR48 EIF3A 25361965 interaction type N/A PTMCode2
EIF3A WDR48 25361965 interaction type N/A PTMCode2
EIF3A EIF3I 25361965 interaction type N/A PTMCode2
EIF3I EIF3A 25361965 interaction type N/A PTMCode2
EIF3A USP3 25361965 interaction type N/A PTMCode2
USP3 EIF3A 25361965 interaction type N/A PTMCode2
EIF3D EIF3A 25361965 interaction type N/A PTMCode2
EIF3A EIF3D 25361965 interaction type N/A PTMCode2
EIF3B EIF3A 25361965 interaction type N/A PTMCode2
EIF3A EIF3B 25361965 interaction type N/A PTMCode2
EIF2S1 EIF3A 25361965 interaction type N/A PTMCode2
EIF3A EIF2S1 25361965 interaction type N/A PTMCode2
EIF3G EIF3A 25361965 interaction type N/A PTMCode2
EIF3A EIF3G 25361965 interaction type N/A PTMCode2
EIF4A1 EIF3A 25361965 interaction type N/A PTMCode2
EIF3A EIF4A1 25361965 interaction type N/A PTMCode2
EIF3C EIF3A 25361965 interaction type N/A PTMCode2
EIF3A EIF3C 25361965 interaction type N/A PTMCode2
EIF3E EIF3A 25361965 interaction type N/A PTMCode2
EIF3A EIF3E 25361965 interaction type N/A PTMCode2
EIF4G1 EIF3A 25361965 interaction type N/A PTMCode2
EIF3A EIF4G1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
NUDT21 EIF3A 25348397 N/A physical interaction ComPPI
EIF3G EIF3A 14525934 18599441 24234451 24396066 25348397 9822659 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,mass spectrometry studies of complexes,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
EIF1B EIF3A 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF3H EIF3A 17353931 18599441 19615732 23623729 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,transmission electron microscopy,mass spectrometry studies of complexes,molecular sieving,pull down,physical interaction,ion exchange chromatography,electron tomography ComPPI,IntAct
NPM1 EIF3A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPS26 EIF3A 25348397 N/A physical interaction ComPPI
RAD21 EIF3A 25348397 N/A physical interaction ComPPI
EIF3E EIF3A 17353931 18599441 23623729 24234451 25348397 association,physical association anti bait coimmunoprecipitation,transmission electron microscopy,mass spectrometry studies of complexes,molecular sieving,pull down,physical interaction,ion exchange chromatography,electron tomography ComPPI,IntAct
LARP1 EIF3A 25348397 N/A physical interaction ComPPI
AIM2 EIF3A 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
RPL10 EIF3A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
REL EIF3A 25348397 N/A physical interaction ComPPI
CD81 EIF3A 25348397 N/A physical interaction ComPPI
JUN EIF3A 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
EIF4G1 EIF3A 25348397 N/A physical interaction,in vivo ComPPI
CPNE2 EIF3A 25348397 N/A physical interaction ComPPI
U2AF2 EIF3A 25348397 N/A physical interaction ComPPI
YWHAZ EIF3A 15161933 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
UBC EIF3A 25348397 N/A physical interaction ComPPI
DLD EIF3A 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
NTRK1 EIF3A 25348397 N/A physical interaction ComPPI
WWP2 EIF3A 25348397 N/A physical interaction ComPPI
RPS3A EIF3A 25348397 N/A physical interaction ComPPI
KRT7 EIF3A 11169732 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid,pull down ComPPI,IntAct
DUSP16 EIF3A 24234451 25348397 28330616 association pull down ComPPI,IntAct
CFTR EIF3A 25348397 N/A physical interaction ComPPI
EIF3C EIF3A 18599441 23623729 24234451 25348397 association,physical association transmission electron microscopy,mass spectrometry studies of complexes,molecular sieving,pull down,physical interaction,ion exchange chromatography,electron tomography ComPPI,IntAct
PDHA1 EIF3A 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
EIF3F EIF3A 17353931 18599441 23623729 24234451 24396066 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,transmission electron microscopy,mass spectrometry studies of complexes,molecular sieving,pull down,physical interaction,ion exchange chromatography,electron tomography ComPPI,IntAct
GRK5 EIF3A 25348397 N/A physical interaction ComPPI
NR4A2 EIF3A 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
RXRB EIF3A 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
RPS25 EIF3A 25348397 N/A physical interaction ComPPI
RPS18 EIF3A 25348397 N/A physical interaction ComPPI
RPLP1 EIF3A 25348397 N/A physical interaction ComPPI
CDK2 EIF3A 25348397 N/A physical interaction ComPPI
CACNA1A EIF3A 21078624 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TFCP2 EIF3A 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
RNF2 EIF3A 25348397 N/A physical interaction ComPPI
CHEK2 EIF3A 23178491 24234451 25348397 association tandem affinity purification ComPPI,IntAct
EIF3I EIF3A 14525934 17353931 18599441 24234451 25348397 8995409 physical association anti bait coimmunoprecipitation,experimental interaction detection,mass spectrometry studies of complexes,physical interaction,in vivo ComPPI,HPRD,IntAct
WWOX EIF3A 25348397 N/A physical interaction ComPPI
SF1 EIF3A 24234451 25348397 26420826 association anti bait coimmunoprecipitation ComPPI,IntAct
VCAM1 EIF3A 22623428 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
ITGA4 EIF3A 25348397 N/A physical interaction ComPPI
EED EIF3A 25348397 N/A physical interaction ComPPI
DNM1L EIF3A 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
RNF139 EIF3A 25348397 N/A physical interaction ComPPI
DDX3X EIF3A 18628297 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF1AX EIF3A 23623729 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
UPF1 EIF3A 14525934 18423202 25348397 N/A anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
TFE3 EIF3A 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SS18 EIF3A 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
TFIP11 EIF3A 25348397 N/A physical interaction ComPPI
WNK1 EIF3A 20936779 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
SEM1 EIF3A 25348397 N/A physical interaction ComPPI
SMURF1 EIF3A 25348397 N/A physical interaction ComPPI
HNRNPF EIF3A 25348397 N/A physical interaction ComPPI
BBS4 EIF3A 18000879 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EIF3J EIF3A 14525934 18599441 23623729 24234451 25348397 9822659 association,physical association transmission electron microscopy,experimental interaction detection,mass spectrometry studies of complexes,molecular sieving,pull down,physical interaction,electron tomography,in vitro,in vivo ComPPI,HPRD,IntAct
EIF4B EIF3A 14525934 16763566 24234451 25348397 8816444 physical association anti tag coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,filter binding,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
EIF4G2 EIF3A 25348397 N/A physical interaction,in vitro,in vivo ComPPI
SRPK2 EIF3A 25348397 N/A physical interaction ComPPI
EIF4A2 EIF3A 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
BRCA1 EIF3A 25348397 N/A physical interaction ComPPI
EIF3D EIF3A 17353931 18599441 23623729 24234451 25348397 association,physical association anti bait coimmunoprecipitation,transmission electron microscopy,mass spectrometry studies of complexes,molecular sieving,pull down,physical interaction,electron tomography ComPPI,IntAct
NAP1L4 EIF3A 25348397 N/A physical interaction ComPPI
EIF3A EIF3B 11169732 14525934 14688252 18599441 18628297 19245811 24234451 25348397 8995410 9822659 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,mass spectrometry studies of complexes,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
EIF3A EIF3L 17353931 18599441 23623729 24234451 25348397 association,physical association anti bait coimmunoprecipitation,transmission electron microscopy,mass spectrometry studies of complexes,molecular sieving,pull down,physical interaction,ion exchange chromatography,electron tomography ComPPI,IntAct
EIF3A EIF4A1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF3A EIF3K 17353931 18599441 23623729 24234451 25348397 association,physical association anti bait coimmunoprecipitation,transmission electron microscopy,mass spectrometry studies of complexes,molecular sieving,pull down,physical interaction,ion exchange chromatography,electron tomography ComPPI,IntAct
EIF3A EIF3M 17353931 18599441 23623729 24234451 25348397 association,physical association anti bait coimmunoprecipitation,transmission electron microscopy,mass spectrometry studies of complexes,molecular sieving,pull down,physical interaction,ion exchange chromatography,electron tomography ComPPI,IntAct
EIF3A MCC 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF3A USP3 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF3A WDR48 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF3A PIK3C2A 25348397 N/A physical interaction ComPPI
EIF3A PRKAG2 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF3A UBA5 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF3A EIF4H 25348397 N/A physical interaction ComPPI
EIF3A NCL 25348397 N/A physical interaction ComPPI
EIF3A MSMO1 25348397 N/A physical interaction ComPPI
EIF3A MYH9 25348397 N/A physical interaction ComPPI
EIF3A MRPL46 25348397 N/A physical interaction ComPPI
EIF3A MYH11 25348397 N/A physical interaction ComPPI
EIF3A TOMM40 25348397 N/A physical interaction ComPPI
EIF3A TUBB6 25348397 N/A physical interaction ComPPI
EIF3A FN1 25348397 N/A physical interaction ComPPI
EIF3A BBS1 18000879 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EIF3A IGSF8 25348397 N/A physical interaction ComPPI
EIF3A ICAM1 25348397 N/A physical interaction ComPPI
EIF3A FBXO6 25348397 N/A physical interaction ComPPI
EIF3A TARDBP 25348397 N/A physical interaction ComPPI
EIF3A DYNC1I2 25348397 N/A physical interaction ComPPI
EIF3A EIF3CL 25348397 N/A physical interaction ComPPI
EIF3A RPS10 25348397 N/A physical interaction ComPPI
EIF3A RPS12 25348397 N/A physical interaction ComPPI
EIF3A RPS20 25348397 N/A physical interaction ComPPI
EIF3A RPS23 25348397 N/A physical interaction ComPPI
EIF3A RPS3 25348397 N/A physical interaction ComPPI
EIF3A RPS9 25348397 N/A physical interaction ComPPI
EIF3A YTHDF2 25348397 N/A physical interaction ComPPI
EIF3A SEM1 25348397 N/A physical interaction ComPPI
EIF3A LGR4 25348397 N/A physical interaction ComPPI
EIF3A RIOK2 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
EIF3A STAU1 25348397 N/A physical interaction ComPPI
EIF3A OBSL1 25348397 N/A physical interaction ComPPI
EIF3A CCDC8 25348397 N/A physical interaction ComPPI
EIF3A BZW2 25348397 N/A physical interaction ComPPI
EIF3A RSPH9 25348397 N/A physical interaction ComPPI
EIF3A PAIP1 24234451 24396066 25348397 association pull down,physical interaction ComPPI,IntAct
EIF3A UNK 25348397 N/A physical interaction ComPPI
EIF3A ABCF2 25348397 N/A physical interaction ComPPI
EIF3A ATP6V0D1 25348397 N/A physical interaction ComPPI
EIF3A HERC2 24234451 25348397 29426014 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF3A HERC2P3 25348397 N/A physical interaction ComPPI
EIF3A AHSA1 25348397 N/A physical interaction ComPPI
EIF3A KIF11 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF3A XRCC3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF3A GAN 25348397 N/A physical interaction ComPPI
EIF3A MEX3C 25348397 N/A physical interaction ComPPI
EIF3A RNF126 25348397 N/A physical interaction ComPPI
EIF3A FAU 25348397 N/A physical interaction ComPPI
EIF3A FAU 25348397 N/A physical interaction ComPPI
EIF3A ZNF746 25348397 N/A physical interaction ComPPI
EIF3A GPBP1L1 25348397 N/A physical interaction ComPPI
EIF3A GPBP1 25348397 N/A physical interaction ComPPI
EIF3A MTNR1B 24234451 25348397 26514267 physical association two hybrid,physical interaction ComPPI,IntAct
EIF3A CYLD 25348397 N/A physical interaction ComPPI
EIF3A SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
EIF3A G3BP1 25348397 N/A physical interaction ComPPI
EIF3A EIF1 23623729 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
EIF3A IKBKE 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
EIF3A ATG12 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
EIF3A INTS6 17469741 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
EIF3A ETS1 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
EIF3A LAMTOR5 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
EIF3A RPTOR 23953116 24234451 25348397 physical association proximity ligation assay ComPPI,IntAct
EIF3A MNDA 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
EIF3A PPM1D 24234451 25348397 28330616 association pull down ComPPI,IntAct
EIF3A PTPN3 24234451 25348397 28330616 association pull down,proximity-dependent biotin identification ComPPI,IntAct
EIF3A PHACTR3 24234451 25348397 28330616 association pull down ComPPI,IntAct
EIF3A PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
SGG EIF3A 25348397 N/A physical interaction,interactome parallel affinity capture ComPPI
FOXO EIF3A 25348397 N/A physical interaction ComPPI
DSOR1 EIF3A 25348397 N/A physical interaction ComPPI
EIF3A PDK1 25348397 N/A physical interaction ComPPI
EIF3A GIMAP8 24234451 30021884 physical association cross-linking study IntAct
EIF3A NLRP12 24234451 30021884 physical association cross-linking study IntAct
HNRNPU EIF3A 24234451 30021884 physical association cross-linking study IntAct
TPT1 EIF3A 24234451 27607350 association anti bait coimmunoprecipitation IntAct

Visualization










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