GeneInfo:
GeneAttribute |
GeneDescription |
GeneSymbol |
ELK4 |
FullNmae |
ETS transcription factor ELK4 |
LocusType |
gene with protein product |
Status |
Approved |
HGNC_id |
HGNC:3326 |
EnsembleID |
ENSG00000158711 |
Uniprot |
P28324 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
ELK4 |
autosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
GeneSymbol |
Go id |
ELK4 |
GO:0000122,GO:0000785,GO:0000978,GO:0000981,GO:0000981,GO:0001228,GO:0003677,GO:0003682,GO:0003700,GO:0005515,GO:0005634,GO:0005654,GO:0005829,GO:0006357,GO:0030154,GO:0045944,GO:1990837 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
MAPK8 |
ELK4 |
23180781
23331499
9020136
|
phosphorylation reaction,stimulation |
in-gel kinase assay |
InnateDB,SignaLink,SignaLink |
MAPK3 |
ELK4 |
23180781
23331499
9020136
|
phosphorylation reaction,stimulation |
in-gel kinase assay |
InnateDB,SignaLink,SignaLink |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
ETS1 |
ELK4 |
18971253
20019798
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
GATA2 |
ELK4 |
18971253
19941826
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
FOXP3 |
ELK4 |
20554955
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array |
TFlink |
SMARCA4 |
ELK4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CEBPA |
ELK4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CTCF |
ELK4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
E2F4 |
ELK4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
EGR1 |
ELK4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
HNF4A |
ELK4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
MITF |
ELK4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
ZNF263 |
ELK4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
AR |
ELK4 |
18469865
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
BRCA1 |
ELK4 |
N/A
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
URS00005651EE |
ELK4 |
23622248
25416803
|
mrna cleavage,inhibition |
clash |
TarBase |
URS0000324096 |
ELK4 |
23622248
25416803
|
mrna cleavage,inhibition |
clash |
TarBase |
URS000018C928 |
ELK4 |
23824327
25416803
27418678
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000236310 |
ELK4 |
23824327
25416803
27418678
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000171CD1 |
ELK4 |
20371350
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000041CB9C |
ELK4 |
20371350
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000040EE1D |
ELK4 |
20371350
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00000F0F49 |
ELK4 |
20371350
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000007D64A |
ELK4 |
20371350
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00004BCD9C |
ELK4 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000040EC3B |
ELK4 |
20371350
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000338542 |
ELK4 |
21572407
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00001D69F6 |
ELK4 |
20371350
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00004CCA62 |
ELK4 |
20371350
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000237AF9 |
ELK4 |
20371350
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000006B702 |
ELK4 |
20371350
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000021D08 |
ELK4 |
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000202460 |
ELK4 |
20371350
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00001E0AEA |
ELK4 |
20371350
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000000E601 |
ELK4 |
20371350
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000027080C |
ELK4 |
20371350
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000508C13 |
ELK4 |
20371350
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000041E949 |
ELK4 |
20371350
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000346991 |
ELK4 |
20371350
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000070CD2 |
ELK4 |
20371350
22012620
23446348
25416803
26701625
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000008F0CF |
ELK4 |
20371350
21572407
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00000DDD35 |
ELK4 |
20371350
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00002075FA |
ELK4 |
20371350
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000298BA3 |
ELK4 |
20371350
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00002B3783 |
ELK4 |
20371350
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000042E1F |
ELK4 |
20371350
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000039E1E1 |
ELK4 |
20371350
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00000600E6 |
ELK4 |
20371350
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000211070 |
ELK4 |
22012620
25416803
26701625
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00000C5BAA |
ELK4 |
21572407
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00001EE123 |
ELK4 |
21572407
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000759FD9 |
ELK4 |
23824327
25416803
27418678
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00004719AB |
ELK4 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00000C7662 |
ELK4 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000076B539 |
ELK4 |
23824327
25416803
27418678
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000057A7C |
ELK4 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00003A5E54 |
ELK4 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00005E1A16 |
ELK4 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000140295 |
ELK4 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000059EB31 |
ELK4 |
25416803
26701625
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00003AD231 |
ELK4 |
25416803
26701625
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00001B9F58 |
ELK4 |
25416803
26701625
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00005485E8 |
ELK4 |
25416803
26701625
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00002C02E4 |
ELK4 |
25416803
26701625
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000075BDAA |
ELK4 |
25416803
26701625
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000049FAE8 |
ELK4 |
25416803
26701625
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00002E0524 |
ELK4 |
25416803
27292025
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000122F23 |
ELK4 |
25416803
27292025
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00002B0B46 |
ELK4 |
25416803
27292025
|
mrna cleavage,inhibition |
clip |
TarBase |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
CDK2 |
ELK4 |
22135298
|
phosphorylation |
N/A |
PhosphoSite |
MAPK11 |
ELK4 |
25361965
|
interaction type |
N/A |
PTMCode2 |
ELK4 |
MAPK11 |
25361965
|
interaction type |
N/A |
PTMCode2 |
SRF |
ELK4 |
25361965
|
interaction type |
N/A |
PTMCode2 |
ELK4 |
SRF |
25361965
|
interaction type |
N/A |
PTMCode2 |
FOS |
ELK4 |
25361965
|
interaction type |
N/A |
PTMCode2 |
ELK4 |
FOS |
25361965
|
interaction type |
N/A |
PTMCode2 |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
MAPK1 |
ELK4 |
25348397
|
N/A |
physical interaction |
ComPPI |
MAPK8 |
ELK4 |
25348397
|
N/A |
physical interaction |
ComPPI |
MAPK3 |
ELK4 |
25348397
|
N/A |
physical interaction |
ComPPI |
SRF |
ELK4 |
11406578
11846562
14525934
17200232
24234451
25348397
7854423
|
N/A |
two hybrid,experimental interaction detection,physical interaction,in vitro |
ComPPI,HPRD,IntAct |
HNRNPL |
ELK4 |
25348397
|
N/A |
physical interaction |
ComPPI |
MAPK7 |
ELK4 |
10473620
14525934
25348397
|
N/A |
experimental interaction detection,in vitro,in vivo |
ComPPI,HPRD |
ID3 |
ELK4 |
10022839
14525934
25348397
|
N/A |
experimental interaction detection,in vitro |
ComPPI,HPRD |
ID1 |
ELK4 |
10022839
14525934
25348397
|
N/A |
experimental interaction detection,in vitro |
ComPPI,HPRD |
ELK4 |
MAPK11 |
25348397
|
N/A |
in vitro |
ComPPI |
ELK4 |
ID2 |
10022839
14525934
25348397
|
N/A |
experimental interaction detection,in vitro |
ComPPI,HPRD |
ELK4 |
BRCA1 |
25348397
|
N/A |
physical interaction |
ComPPI |
ELK4 |
ELAVL1 |
25348397
|
N/A |
physical interaction |
ComPPI |
ELK4 |
TRIM25 |
25348397
|
N/A |
physical interaction |
ComPPI |
ELK4 |
SIRT7 |
22722849
24234451
25348397
|
physical association |
anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
ELK4 |
FOS |
14525934
7540136
|
N/A |
experimental interaction detection |
HPRD |
CDK2 |
ELK4 |
26028036
27898060
|
N/A |
N/A |
OmniPath |
MAPK3 |
ELK4 |
27898060
9020136
|
stimulant |
N/A |
OmniPath |
ELK4 |
MAPK3 |
27898060
9020136
|
N/A |
N/A |
OmniPath |
MAPK8 |
ELK4 |
27898060
9020136
|
stimulant |
N/A |
OmniPath |
PCSK7 |
ELK4 |
27898060
9130707
|
stimulant |
N/A |
OmniPath |
Visualization