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GENE：SPRED1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SPRED1
FullNmae sprouty related EVH1 domain containing 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:20249
EnsembleID ENSG00000166068
Uniprot Q7Z699

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SPRED1 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SPRED1 GO:0005173,GO:0005515,GO:0005654,GO:0005829,GO:0005829,GO:0005886,GO:0005886,GO:0005901,GO:0006469,GO:0010719,GO:0010801,GO:0016525,GO:0019901,GO:0019901,GO:0019902,GO:0030291,GO:0030512,GO:0031410,GO:0043408,GO:0043409,GO:0043409,GO:0043517,GO:0060979,GO:0070373,GO:0090051,GO:0090311,GO:1902747

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SPRED1 ELAVL1 19322201 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR SPRED1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 SPRED1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 SPRED1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 SPRED1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 SPRED1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 SPRED1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SPRED1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SPRED1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SPRED1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SPRED1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SPRED1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SPRED1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SPRED1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SPRED1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 SPRED1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 SPRED1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 SPRED1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001D69F6 SPRED1 18694566 18832181 18987025 22525256 \N rna interference,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00001D69F6 SPRED1 18694566 18832181 18927107 18987025 22525256 23811937 25416803 26381870 28100645 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay miR2Disease,TarBase
URS0000237AF9 SPRED1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00000ED600 SPRED1 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS0000028BB8 SPRED1 17612493 25416803 25945589 mrna cleavage,inhibition array technology,western blot,miRNA interference luciferase reporter assay TarBase
URS00000DDD35 SPRED1 20371350 23592263 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS0000171CD1 SPRED1 22473208 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000028D811 SPRED1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000572E11 SPRED1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C SPRED1 22473208 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000821E0 SPRED1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D SPRED1 22473208 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 SPRED1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A SPRED1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000021D08 SPRED1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002E1509 SPRED1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001EFEC1 SPRED1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000475586 SPRED1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF SPRED1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000025EABA SPRED1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001EE123 SPRED1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5BAA SPRED1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004719AB SPRED1 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000FFE5F SPRED1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000012930C SPRED1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000002CF68 SPRED1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000000E601 SPRED1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA SPRED1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F SPRED1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 SPRED1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 SPRED1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 SPRED1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 SPRED1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C SPRED1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 SPRED1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 SPRED1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 SPRED1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 SPRED1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000355E82 SPRED1 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS0000215483 SPRED1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00004977C5 SPRED1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000048BA36 SPRED1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000001EB3 SPRED1 23592263 25416803 26657862 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS00003E6EFA SPRED1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002394F5 SPRED1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075D15B SPRED1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000009A9A2 SPRED1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001310DE SPRED1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000081D1E SPRED1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 SPRED1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002CAE0C SPRED1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000338542 SPRED1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000F6E49 SPRED1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000AD002 SPRED1 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS00000C85B2 SPRED1 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 SPRED1 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS000007F792 SPRED1 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB0E SPRED1 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 SPRED1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000040780F SPRED1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004214BB SPRED1 21572407 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SPRED1 TESK1 25361965 interaction type N/A PTMCode2
TESK1 SPRED1 25361965 interaction type N/A PTMCode2
KIT SPRED1 25361965 interaction type N/A PTMCode2
SPRED1 KIT 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
ZNF408 SPRED1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FAM90A1 SPRED1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HEXIM2 SPRED1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CDKN1A SPRED1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NCALD SPRED1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAB21L3 SPRED1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CCDC185 SPRED1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
VSNL1 SPRED1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HPCAL4 SPRED1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RIN1 SPRED1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KIT SPRED1 12646235 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SPRED1 PPP1CA 14525934 15231748 19389623 22321011 24234451 25348397 physical association two hybrid,far western blotting,pull down,physical interaction,two hybrid ComPPI,HPRD,IntAct
SPRED1 TESK1 25348397 N/A physical interaction ComPPI
SPRED1 OSGEP 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SPRED1 DNAJB11 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SPRED1 NAGK 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SPRED1 RCC1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SPRED1 TSC22D1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SPRED1 ELAVL1 25348397 N/A physical interaction ComPPI
SPRED1 SUV39H1 23455924 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SPRED1 ZDHHC17 24234451 24705354 25348397 physical association two hybrid,physical interaction,two hybrid array,luminescence based mammalian interactome mapping ComPPI,IntAct
SPRED1 CDH1 25348397 N/A physical interaction ComPPI
SPRED1 TRIM25 25348397 N/A physical interaction ComPPI
SPRED1 PPP1R7 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
SPRED1 PIH1D2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SPRED1 BLZF1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SPRED1 ZNF587 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SPRED1 GLYCTK 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SPRED1 ZNF417 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SPRED1 SPG21 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SPRED1 AQP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SPRED1 PRPF18 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SPRED1 BEX2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SPRED1 HSF2BP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SPRED1 C2ORF68 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SPRED1 ZNF655 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TTC19 SPRED1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
FAM118B SPRED1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
KIT SPRED1 11493923 12646235 27898060 N/A N/A OmniPath

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