GENE:GAREM1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | GAREM1 |
| FullNmae | GRB2 associated regulator of MAPK1 subtype 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:26136 |
| EnsembleID | ENSG00000141441 |
| Uniprot | Q9H706 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| GAREM1 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| GAREM1 | GO:0005515,GO:0005886,GO:0007173,GO:0007173,GO:0008284,GO:0051781,GO:0070064,GO:0070064,GO:0070374,GO:0071364,GO:0071364 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | GAREM1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ESR1 | GAREM1 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | GAREM1 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA3 | GAREM1 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXA1 | GAREM1 | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | GAREM1 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| PRDM14 | GAREM1 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | GAREM1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | GAREM1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | GAREM1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | GAREM1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | GAREM1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | GAREM1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | GAREM1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | GAREM1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | GAREM1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | GAREM1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| NCK2 | GAREM1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| CRK | GAREM1 | 24234451 25348397 25814554 | physical association | two hybrid,physical interaction,two hybrid array,validated two hybrid | ComPPI,IntAct |
| CRKL | GAREM1 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| GRAP2 | GAREM1 | 24234451 25348397 25814554 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| SHC1 | GAREM1 | 25348397 | N/A | physical interaction | ComPPI |
| GRB2 | GAREM1 | 20936779 21706016 21988832 24234451 25348397 25416956 | association,physical association | anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| NTRK1 | GAREM1 | 25348397 | N/A | physical interaction | ComPPI |
| EFNA1 | GAREM1 | 25348397 | N/A | physical interaction | ComPPI |
| XPO1 | GAREM1 | 25348397 | N/A | physical interaction | ComPPI |
| SHC4 | GAREM1 | 25348397 | N/A | physical interaction | ComPPI |
