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GENE：GPI

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GPI
FullNmae glucose-6-phosphate isomerase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4458
EnsembleID ENSG00000105220
Uniprot P06744

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GPI autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GPI GO:0001701,GO:0001707,GO:0002639,GO:0004347,GO:0004347,GO:0005125,GO:0005515,GO:0005576,GO:0005829,GO:0005829,GO:0005975,GO:0006094,GO:0006096,GO:0006096,GO:0006959,GO:0007165,GO:0007599,GO:0007611,GO:0008083,GO:0010595,GO:0016020,GO:0031625,GO:0032355,GO:0032570,GO:0033574,GO:0034101,GO:0034774,GO:0035902,GO:0035994,GO:0042593,GO:0043524,GO:0046686,GO:0048029,GO:0051156,GO:0051156,GO:0060170,GO:0070062,GO:0097367,GO:1904813

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
GPI hsa:2821 path:hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human)
GPI hsa:2821 path:hsa00030 Pentose phosphate pathway - Homo sapiens (human)
GPI hsa:2821 path:hsa00500 Starch and sucrose metabolism - Homo sapiens (human)
GPI hsa:2821 path:hsa00520 Amino sugar and nucleotide sugar metabolism - Homo sapiens (human)
GPI hsa:2821 path:hsa01100 Metabolic pathways - Homo sapiens (human)
GPI hsa:2821 path:hsa01200 Carbon metabolism - Homo sapiens (human)
GPI hsa:2821 path:hsa01250 Biosynthesis of nucleotide sugars - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ISG15 GPI 16009940 23180781 physical association unspecified method InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 GPI 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 GPI 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
HIF1A GPI 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
YBX1 GPI 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 GPI 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 GPI 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 GPI 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 GPI 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000018C928 GPI \N rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00000EED18 GPI 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000079D48 GPI 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000002103A GPI 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000512C88 GPI 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001A7F58 GPI 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C3AC1 GPI 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000042E1F GPI 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002B7450 GPI 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000AA464 GPI 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000134ADC GPI 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001597DC GPI 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C770D GPI 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002075FA GPI 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 GPI 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000013ABA3 GPI 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000451A1 GPI 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000475586 GPI 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000078918 GPI 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CSNK2A1 GPI 22135298 phosphorylation N/A PhosphoSite
AMFR GPI 25361965 interaction type N/A PTMCode2
GPI AMFR 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SNRPB2 GPI 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
BAG3 GPI 25348397 N/A physical interaction ComPPI
ISG15 GPI 25348397 N/A physical interaction ComPPI
PCNA GPI 25348397 N/A physical interaction ComPPI
GABARAPL2 GPI 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
KEAP1 GPI 25348397 N/A physical interaction ComPPI
MAP1LC3B GPI 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PEF1 GPI 25348397 N/A physical interaction ComPPI
RAB10 GPI 25348397 N/A physical interaction ComPPI
SND1 GPI 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
JUN GPI 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
EIF5B GPI 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
U2AF2 GPI 25348397 N/A physical interaction ComPPI
PDIA3 GPI 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
UBE2N GPI 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PGM1 GPI 25348397 N/A physical interaction ComPPI
NTRK1 GPI 25348397 N/A physical interaction ComPPI
IDH2 GPI 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ENO1 GPI 25348397 N/A physical interaction ComPPI
CSNK2A1 GPI 11004567 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
DUSP7 GPI 24234451 25348397 28330616 association pull down ComPPI,IntAct
PA2G4 GPI 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CFTR GPI 25348397 N/A physical interaction ComPPI
TRAP1 GPI 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
HUWE1 GPI 25348397 N/A physical interaction ComPPI
TPI1 GPI 25348397 N/A physical interaction ComPPI
PPA1 GPI 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK2 GPI 25348397 N/A physical interaction ComPPI
PRDX6 GPI 25348397 N/A physical interaction ComPPI
CUL7 GPI 25348397 N/A physical interaction ComPPI
FOXA1 GPI 25348397 N/A physical interaction ComPPI
WDR1 GPI 25348397 N/A physical interaction ComPPI
AMFR GPI 14525934 16563432 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PDCD6IP GPI 25348397 N/A physical interaction ComPPI
BRCA1 GPI 25348397 N/A physical interaction ComPPI
PPM1D GPI 24234451 25348397 28330616 association pull down ComPPI,IntAct
IGFBP3 GPI 14525934 15059907 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
GPI PARP14 14525934 17875708 25348397 27898060 N/A experimental interaction detection,physical interaction ComPPI,HPRD,OmniPath
GPI CCP110 25348397 N/A physical interaction ComPPI
GPI NEURL4 25348397 N/A physical interaction ComPPI
GPI TMEM256 25348397 N/A physical interaction ComPPI
GPI ENO3 25348397 N/A physical interaction ComPPI
GPI ASB15 25348397 N/A physical interaction ComPPI
GPI FUS 25348397 N/A physical interaction ComPPI
GPI OBSL1 25348397 N/A physical interaction ComPPI
GPI ALDH4A1 25348397 N/A physical interaction ComPPI
GPI ANXA7 25348397 N/A physical interaction ComPPI
GPI FH 25348397 N/A physical interaction ComPPI
GPI ABAT 25348397 N/A physical interaction ComPPI
GPI AKR1A1 25348397 N/A physical interaction ComPPI
GPI GOT2 25348397 N/A physical interaction ComPPI
GPI MRPL45 25348397 N/A physical interaction ComPPI
GPI SDHB 25348397 N/A physical interaction ComPPI
GPI SORD 25348397 N/A physical interaction ComPPI
GPI TKT 25348397 N/A physical interaction ComPPI
GPI SPICE1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
GPI PPME1 25348397 N/A physical interaction ComPPI
GPI TAMM41 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GPI SPRYD4 25348397 N/A physical interaction ComPPI
GPI ADCK2 25348397 N/A physical interaction ComPPI
GPI ANXA5 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GPI NANS 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GPI PLS3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GPI SLC25A10 25348397 N/A physical interaction ComPPI
GPI CRNN 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GPI ZNF207 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GPI CPNE3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GPI CS 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GPI TES 25348397 N/A physical interaction ComPPI
GPI PPTC7 24234451 25348397 28330616 association pull down ComPPI,IntAct
GPI PHOSPHO1 24234451 25348397 28330616 association pull down ComPPI,IntAct
GPI TRUB2 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
GPI COQ8A 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
HPRT1 GPI 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MRPL12 GPI 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
DCXR GPI 25348397 N/A physical interaction ComPPI
ESD GPI 25348397 N/A physical interaction ComPPI
LACTB2 GPI 25348397 N/A physical interaction ComPPI
GPI GPI 14525934 15637053 N/A experimental interaction detection HPRD
SMARCB1 GPI 24234451 30108113 association proximity-dependent biotin identification IntAct
CSNK2A1 GPI 11004567 15637053 27898060 inhibition N/A OmniPath
ISG15 GPI 16009940 16139798 27898060 N/A N/A OmniPath
GPI AMFR 12527360 16563432 24810856 27898060 stimulant N/A OmniPath

Visualization










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