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GENE：GPRC5A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GPRC5A
FullNmae G protein-coupled receptor class C group 5 member A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9836
EnsembleID ENSG00000013588
Uniprot Q8NFJ5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GPRC5A autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GPRC5A GO:0004930,GO:0005515,GO:0005730,GO:0005886,GO:0005886,GO:0007165,GO:0007175,GO:0007186,GO:0030295,GO:0030659,GO:0031982,GO:0043231,GO:0043231,GO:0043235,GO:0045296,GO:0070062,GO:0070062

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR GPRC5A 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 GPRC5A 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA2 GPRC5A 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
RARA GPRC5A 18971253 19279407 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
RARG GPRC5A 19279407 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
RXRA GPRC5A 19279407 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
RXRB GPRC5A 19279407 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C GPRC5A 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 GPRC5A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GPRC5A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 GPRC5A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS GPRC5A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A GPRC5A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF GPRC5A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 GPRC5A 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000065D58 GPRC5A 18668040 23824327 25416803 mrna cleavage,inhibition experimental interaction detection,clip TarBase
URS000003ABC4 GPRC5A 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00003BBF48 GPRC5A 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000315338 GPRC5A 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000000C73C GPRC5A 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001C11BC GPRC5A 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002C0FCB GPRC5A 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000521626 GPRC5A 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000031602A GPRC5A 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000251D0B GPRC5A 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000585553 GPRC5A 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000237E04 GPRC5A 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000235862 GPRC5A 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001012BC GPRC5A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000383DF4 GPRC5A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000116F83 GPRC5A 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002A79D1 GPRC5A 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002CCA6E GPRC5A 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000254A6 GPRC5A 23313552 23824327 24906430 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000076B539 GPRC5A 23313552 23824327 24906430 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000008F0CF GPRC5A 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A GPRC5A 23313552 23824327 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000F0F49 GPRC5A 23313552 23824327 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000040EE1D GPRC5A 23313552 23824327 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000171CD1 GPRC5A 23313552 23824327 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000041CB9C GPRC5A 23824327 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001B12A4 GPRC5A 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001AFC71 GPRC5A 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000CC005 GPRC5A 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 GPRC5A 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001DE669 GPRC5A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F GPRC5A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000D0BB4 GPRC5A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000153377 GPRC5A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075E2C3 GPRC5A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000028DE3F GPRC5A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002F5FEE GPRC5A 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000006B702 GPRC5A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000753AD GPRC5A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001C0099 GPRC5A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000043C1C3 GPRC5A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000041FA2C GPRC5A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000027352D GPRC5A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D GPRC5A 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002152A8 GPRC5A 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000B989F GPRC5A 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075A760 GPRC5A 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004F859B GPRC5A 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000045147B GPRC5A 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
EGFR GPRC5A 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
GTF2F2 GPRC5A 25348397 N/A physical interaction ComPPI
RAB7A GPRC5A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDH1 GPRC5A 25348397 N/A physical interaction ComPPI
CFTR GPRC5A 25348397 N/A physical interaction ComPPI
ATP6AP2 GPRC5A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NOLC1 GPRC5A 25348397 N/A physical interaction ComPPI
HSPA9 GPRC5A 25348397 N/A physical interaction ComPPI
TRIM25 GPRC5A 25348397 N/A physical interaction ComPPI
SYNPO GPRC5A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF4A1 GPRC5A 25348397 N/A physical interaction ComPPI
RAB5C GPRC5A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ACTR2 GPRC5A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYH9 GPRC5A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LIMA1 GPRC5A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SLC25A3 GPRC5A 25348397 N/A physical interaction ComPPI
DBN1 GPRC5A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLEKHA7 GPRC5A 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
GOLT1B GPRC5A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MPV17 GPRC5A 25348397 N/A physical interaction ComPPI
GPRC5A TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
GPRC5A MYO19 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GAPDH GPRC5A 24234451 30021884 physical association cross-linking study IntAct
EGFR GPRC5A 25311788 27898060 N/A N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00008B90A6 GPRC5A 27087310 direct interaction,inhibition N/A NPInter

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