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GENE：KDM3A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol KDM3A
FullNmae lysine demethylase 3A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:20815
EnsembleID ENSG00000115548
Uniprot Q9Y4C1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
KDM3A autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
KDM3A GO:0000118,GO:0000785,GO:0001673,GO:0003712,GO:0005506,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0006338,GO:0006357,GO:0007290,GO:0009755,GO:0016020,GO:0030521,GO:0031490,GO:0032454,GO:0032454,GO:0045893,GO:0045944,GO:0046293,GO:0050681,GO:0120162,GO:0140683,GO:1990830,GO:2000036,GO:2000736

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
KDM3A hsa:55818 path:hsa04714 Thermogenesis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EGR1 KDM3A 19374776 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F6 KDM3A 12909625 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 KDM3A 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 KDM3A 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 KDM3A 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
HIF1A KDM3A 18971253 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
SMARCA4 KDM3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA KDM3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 KDM3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 KDM3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 KDM3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 KDM3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS KDM3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A KDM3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 KDM3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 KDM3A 21541331 rna interference,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay miRSponge
URS0000338542 KDM3A 21541331 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS00001A7F58 KDM3A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000040FA88 KDM3A 23619147 25416803 mrna cleavage,inhibition experimental interaction detection,western blot TarBase
URS00001DE669 KDM3A 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F KDM3A 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 KDM3A 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000065D58 KDM3A 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PRKACA KDM3A 22135298 phosphorylation N/A PhosphoSite
TNK2 KDM3A 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
STAT1 KDM3A 25348397 N/A anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI
AR KDM3A 25348397 N/A physical interaction ComPPI
HIF1A KDM3A 25348397 N/A physical interaction ComPPI
CBX4 KDM3A 25348397 N/A physical interaction ComPPI
HUWE1 KDM3A 25348397 N/A physical interaction ComPPI
RPS6KA5 KDM3A 24234451 25348397 25535969 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,phosphorylation reaction,physical interaction,protein kinase assay ComPPI,IntAct
H3C15 KDM3A 25348397 N/A physical interaction ComPPI
STAT6 KDM3A 25348397 N/A physical interaction ComPPI
TNK2 KDM3A 25348397 N/A physical interaction ComPPI
RIPK2 KDM3A 23455924 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MYOCD KDM3A 25348397 N/A physical interaction ComPPI
MRTFA KDM3A 25348397 N/A physical interaction ComPPI
MRTFB KDM3A 25348397 N/A physical interaction ComPPI
POLR2F KDM3A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TCEAL1 KDM3A 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CBX2 KDM3A 21282530 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
RTRAF KDM3A 25348397 N/A physical interaction ComPPI
EIF4H KDM3A 25348397 N/A physical interaction ComPPI
IRF2BP1 KDM3A 25348397 N/A physical interaction ComPPI
ECPAS KDM3A 25348397 N/A physical interaction ComPPI
GART KDM3A 25348397 N/A physical interaction ComPPI
KDM3A ETV2 16619273 25348397 27898060 N/A physical interaction ComPPI,OmniPath
KDM3A RASSF6 25348397 N/A physical interaction ComPPI
KDM3A ARFGAP2 25348397 N/A physical interaction ComPPI
KDM3A ARPP19 25348397 N/A physical interaction ComPPI
KDM3A GFUS 25348397 N/A physical interaction ComPPI
PRKACA KDM3A 25948511 27898060 N/A N/A OmniPath
KDM3A H3C1 18022353 27898060 stimulant N/A OmniPath
KDM3A AR 17363312 17909537 27898060 stimulant N/A OmniPath
TNK2 KDM3A 25148682 27898060 N/A N/A OmniPath

Visualization










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