Gene Information gene info

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GENE：KLF6

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol KLF6
FullNmae KLF transcription factor 6
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2235
EnsembleID ENSG00000067082
Uniprot Q99612

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
KLF6 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
KLF6 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
KLF6 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
KLF6 GO:0000785,GO:0000978,GO:0000978,GO:0000981,GO:0000981,GO:0001228,GO:0001650,GO:0005515,GO:0005634,GO:0005654,GO:0005730,GO:0005829,GO:0006357,GO:0030183,GO:0043231,GO:0045893,GO:0045944,GO:0046872,GO:1990837

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CDH1 KLF6 16702959 23180781 physical association anti tag coimmunoprecipitation InnateDB
NOS2 KLF6 12590140 23180781 physical association anti tag coimmunoprecipitation InnateDB
KLF6 RELA 23180781 24634218 physical association anti tag coimmunoprecipitation InnateDB
KLF6 NFKBIA 23180781 24634218 physical association anti tag coimmunoprecipitation InnateDB
KLF6 CXCL8 23180781 24634218 physical association anti tag coimmunoprecipitation InnateDB
KLF6 CCL2 23180781 24634218 physical association anti tag coimmunoprecipitation InnateDB
KLF6 CXCL2 23180781 24634218 physical association anti tag coimmunoprecipitation InnateDB
KLF6 PPARG 23180781 25686501 physical association anti tag coimmunoprecipitation InnateDB
KLF6 PPARA 23180781 25686501 physical association anti tag coimmunoprecipitation InnateDB
KLF6 PPARD 23180781 25686501 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR KLF6 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 KLF6 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 KLF6 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXO3 KLF6 18226221 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA1 KLF6 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 KLF6 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 KLF6 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 KLF6 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 KLF6 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 KLF6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA KLF6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF KLF6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 KLF6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 KLF6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS KLF6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A KLF6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF KLF6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 KLF6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 KLF6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 KLF6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 KLF6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
NR1I2 KLF6 21072196 trascriptional regulation,stimulation inferred by curator TFlink
TP53 KLF6 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000521626 KLF6 23592263 23622248 25416803 mrna cleavage,inhibition clip,clash TarBase
URS00002233F4 KLF6 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000025EABA KLF6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001F14FE KLF6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001D4A78 KLF6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000018C928 KLF6 24397367 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,quantitative reverse transcription pcr TarBase
URS00002B3783 KLF6 23592263 24397367 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,quantitative reverse transcription pcr,clip TarBase
URS0000171CD1 KLF6 24397367 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,quantitative reverse transcription pcr TarBase
URS00000FFE5F KLF6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004719AB KLF6 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000061E50F KLF6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001481F9 KLF6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000005A8ED KLF6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000572E11 KLF6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000028D811 KLF6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 KLF6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 KLF6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F KLF6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 KLF6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA KLF6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 KLF6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000006F90B KLF6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003BBF48 KLF6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000000C73C KLF6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000251D0B KLF6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A KLF6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB KLF6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC KLF6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 KLF6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000007FBA KLF6 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000B7E30 KLF6 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA KLF6 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 KLF6 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00005606AA KLF6 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000028DE3F KLF6 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TAF9 KLF6 25348397 N/A physical interaction ComPPI
EHMT2 KLF6 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SP1 KLF6 12433697 14525934 22169644 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
HDAC3 KLF6 14525934 15917248 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
E2F1 KLF6 25348397 N/A physical interaction ComPPI
RELA KLF6 24234451 24634218 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct
NR0B2 KLF6 25348397 N/A physical interaction ComPPI
KLF6 KLF4 10802067 25348397 27898060 N/A physical interaction,in vivo ComPPI,OmniPath
KLF6 CELSR2 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
KLF6 APOM 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
KLF6 GTF3C1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
KLF6 POLA2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
KLF6 PNO1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
KLF6 NUFIP1 25348397 N/A physical interaction ComPPI
KLF6 AK6 25348397 N/A physical interaction ComPPI
KLF6 FBL 25348397 N/A physical interaction ComPPI
KLF6 NOP56 25348397 N/A physical interaction ComPPI
KLF6 LCOR 22277651 25348397 27898060 N/A physical interaction ComPPI,OmniPath
KLF6 APP 25348397 N/A physical interaction ComPPI
KLF6 RUNX1 25348397 N/A physical interaction ComPPI
KLF6 TRIM25 25348397 N/A physical interaction ComPPI
KLF6 TP53 14525934 15131018 27898060 N/A experimental interaction detection HPRD,OmniPath
CCL2 KLF6 24234451 24634218 association chromatin immunoprecipitation assay IntAct
KLF6 NFKBIA 24234451 24634218 association chromatin immunoprecipitation assay IntAct
KLF6 RELA 24634218 27898060 N/A N/A OmniPath
KLF6 DAPK2 18521079 27898060 stimulant N/A OmniPath
KLF6 PTTG1 20116377 27898060 inhibition N/A OmniPath

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