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GENE：KMT2B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol KMT2B
FullNmae lysine methyltransferase 2B
LocusType gene with protein product
Status Approved
HGNC_id HGNC:15840
EnsembleID ENSG00000272333
Uniprot Q9UMN6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
KMT2B autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
KMT2B GO:0005515,GO:0005634,GO:0005654,GO:0006338,GO:0008270,GO:0032259,GO:0035097,GO:0035097,GO:0042800,GO:0042800,GO:0042800,GO:0044665,GO:0045322,GO:0045893,GO:0051568,GO:0140945,GO:0140999

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
KMT2B hsa:9757 path:hsa00310 Lysine degradation - Homo sapiens (human)
KMT2B hsa:9757 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 KMT2B 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA1 KMT2B 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 KMT2B 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 KMT2B 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 KMT2B 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink

Source Target Pmid Interactiontype Methods Database
URS0000070CD2 KMT2B 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000519450 KMT2B 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 KMT2B 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE KMT2B 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000012930C KMT2B 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 KMT2B 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 KMT2B 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F KMT2B 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA KMT2B 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 KMT2B 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 KMT2B 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 KMT2B 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000435A77 KMT2B 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001C85C7 KMT2B 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000160683 KMT2B 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000001EB3 KMT2B 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000BE495 KMT2B 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003BFB30 KMT2B 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000024CEE0 KMT2B 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000032D69B KMT2B 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000585553 KMT2B 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000246356 KMT2B 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PIN1 KMT2B 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DPY30 KMT2B 23995757 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ANXA1 KMT2B 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CDKN1A KMT2B 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TK1 KMT2B 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TP53BP1 KMT2B 19433796 24234451 25348397 physical association molecular sieving,ion exchange chromatography ComPPI,IntAct
ATXN1 KMT2B 16713569 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ZNF512B KMT2B 15231748 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SMN1 KMT2B 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CRK KMT2B 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
GRB7 KMT2B 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NCK1 KMT2B 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
GRB2 KMT2B 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
HCFC1 KMT2B 25348397 N/A anti tag coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI
SMAD3 KMT2B 15231748 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PAXIP1 KMT2B 25348397 N/A physical interaction ComPPI
PIK3R3 KMT2B 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PRPF40A KMT2B 25348397 N/A in vitro ComPPI
NCOA6 KMT2B 17021013 19047629 19433796 24234451 25348397 association,physical association anti bait coimmunoprecipitation,molecular sieving,physical interaction,ion exchange chromatography ComPPI,IntAct
ASH2L KMT2B 23995757 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
CSNK2A1 KMT2B 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
RAP1B KMT2B 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RCC1 KMT2B 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RBBP5 KMT2B 23995757 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SMARCB1 KMT2B 25348397 N/A physical interaction ComPPI
WDR77 KMT2B 23995757 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATP1B1 KMT2B 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PSTPIP1 KMT2B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
H3C15 KMT2B 25348397 N/A physical interaction ComPPI
PSIP1 KMT2B 23995757 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FYN KMT2B 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
H3C1 KMT2B 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
HNRNPF KMT2B 23995757 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KHSRP KMT2B 23995757 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SEPTIN8 KMT2B 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
KMT2B BCL6 16147992 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
KMT2B NREP 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
KMT2B ANXA7 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
KMT2B THOC2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KMT2B HCFC2 25348397 N/A physical interaction ComPPI
KMT2B MEN1 23995757 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,isothermal titration calorimetry,physical interaction ComPPI,IntAct
KMT2B MAP1B 23995757 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KMT2B ABL1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
KMT2B KMT2A 18840606 24234451 25348397 N/A pull down ComPPI,IntAct
KMT2B FOXK2 24234451 25348397 25609649 association tandem affinity purification ComPPI,IntAct
KMT2B AKAP8 23995757 24234451 25348397 physical association molecular sieving ComPPI,IntAct
KMT2B TOPBP1 17913746 24234451 25348397 physical association two hybrid ComPPI,IntAct
WDR5 KMT2B 23995757 24234451 24788516 25348397 27705803 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,isothermal titration calorimetry,physical interaction,tandem affinity purification ComPPI,IntAct
KMT2B H3C1 18022353 19219072 27898060 stimulant N/A OmniPath
KMT2B RELB 19219072 27898060 stimulant N/A OmniPath

Visualization










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