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GENE：MPC1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MPC1
FullNmae mitochondrial pyruvate carrier 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:21606
EnsembleID ENSG00000060762
Uniprot Q9Y5U8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MPC1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MPC1 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
MPC1 GO:0003674,GO:0005515,GO:0005739,GO:0005743,GO:0006850,GO:0006850,GO:0006850,GO:0008150,GO:0050833,GO:0098800

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MPC1 hsa:51660 path:hsa05415 Diabetic cardiomyopathy - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR MPC1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 MPC1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 MPC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MPC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MPC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MPC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 MPC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MPC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MPC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MPC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 MPC1 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00001597DC MPC1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
GABARAP MPC1 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MAGED1 MPC1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct

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