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GENE：PDLIM5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PDLIM5
FullNmae PDZ and LIM domain 5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17468
EnsembleID ENSG00000163110
Uniprot Q96HC4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PDLIM5 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PDLIM5 GO:0001725,GO:0003779,GO:0003779,GO:0005080,GO:0005515,GO:0005829,GO:0005912,GO:0005912,GO:0007507,GO:0014069,GO:0015629,GO:0016020,GO:0030018,GO:0030036,GO:0031941,GO:0042805,GO:0042995,GO:0046872,GO:0051371,GO:0051963,GO:0061001,GO:0061049,GO:0061061,GO:0098609,GO:0098641,GO:0098793

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SUZ12 PDLIM5 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
RNF2 PDLIM5 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR PDLIM5 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 PDLIM5 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ESR1 PDLIM5 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 PDLIM5 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 PDLIM5 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 PDLIM5 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 PDLIM5 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 PDLIM5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PDLIM5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PDLIM5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PDLIM5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PDLIM5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PDLIM5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PDLIM5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PDLIM5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 PDLIM5 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 PDLIM5 N/A 20584899 rna interference,inhibition experimental interaction detection,western blot miRSponge
URS0000338542 PDLIM5 18668040 20584899 25416803 mrna cleavage,inhibition experimental interaction detection,western blot TarBase
URS00002075FA PDLIM5 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000277201 PDLIM5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005C1F22 PDLIM5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E PDLIM5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001CE046 PDLIM5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000032835F PDLIM5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000166778 PDLIM5 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000016914 PDLIM5 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001A4ABF PDLIM5 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00003AFAD1 PDLIM5 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000324096 PDLIM5 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000031E12 PDLIM5 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000A07C1 PDLIM5 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000000B1C9 PDLIM5 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000029979D PDLIM5 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000237CBD PDLIM5 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000009A9A2 PDLIM5 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000AA464 PDLIM5 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000383DF4 PDLIM5 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000042935A PDLIM5 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000032EF64 PDLIM5 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000011A030 PDLIM5 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000023F008 PDLIM5 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000122ED0 PDLIM5 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CBSL PDLIM5 25348397 N/A physical interaction ComPPI
HSPA8 PDLIM5 24234451 25348397 29568061 association pull down ComPPI,IntAct
SYT11 PDLIM5 25348397 N/A physical interaction ComPPI
CEP19 PDLIM5 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
RWDD2B PDLIM5 25348397 N/A physical interaction ComPPI
KRTAP10-7 PDLIM5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
COIL PDLIM5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ACTB PDLIM5 25348397 N/A in vitro ComPPI
BMI1 PDLIM5 25348397 N/A physical interaction ComPPI
KRT40 PDLIM5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ZYX PDLIM5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
DSTN PDLIM5 25348397 N/A physical interaction ComPPI
TPM2 PDLIM5 25348397 N/A physical interaction ComPPI
PRKCE PDLIM5 25348397 N/A two hybrid,physical interaction ComPPI
ACTN1 PDLIM5 25348397 N/A in vitro ComPPI
NTRK1 PDLIM5 25348397 N/A physical interaction ComPPI
CDH1 PDLIM5 25348397 N/A physical interaction ComPPI
BTRC PDLIM5 25348397 N/A physical interaction ComPPI
ILK PDLIM5 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SIN3A PDLIM5 25348397 N/A physical interaction ComPPI
PPP1CA PDLIM5 24234451 25348397 25593058 association anti bait coimmunoprecipitation ComPPI,IntAct
MAP2K1 PDLIM5 25348397 N/A physical interaction ComPPI
PRKCB PDLIM5 25348397 N/A two hybrid,physical interaction,in vivo ComPPI
MAP2K2 PDLIM5 25348397 N/A physical interaction ComPPI
ANP32A PDLIM5 25348397 N/A physical interaction ComPPI
PDLIM7 PDLIM5 25348397 N/A physical interaction ComPPI
PDLIM5 PRKCG 25348397 N/A two hybrid ComPPI
PDLIM5 CACNA1B 12665800 25348397 27898060 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI,OmniPath
PDLIM5 TRIM39 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PDLIM5 GFI1B 16713569 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PDLIM5 NDUFA7 25348397 N/A physical interaction ComPPI
PDLIM5 MIDEAS 25348397 N/A physical interaction ComPPI
PDLIM5 FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
PDLIM5 METTL1 25348397 N/A physical interaction ComPPI
PDLIM5 NPLOC4 25348397 N/A physical interaction ComPPI
PDLIM5 PDE12 25348397 N/A physical interaction ComPPI
PDLIM5 CBS 25348397 N/A physical interaction ComPPI
PDLIM5 IPO11 25348397 N/A physical interaction ComPPI
PDLIM5 PLIN3 25348397 N/A physical interaction ComPPI
PDLIM5 SRP14 25348397 N/A physical interaction ComPPI
PDLIM5 UBA2 25348397 N/A physical interaction ComPPI
PDLIM5 RAD23B 25348397 N/A physical interaction ComPPI
PDLIM5 TPD52 25348397 N/A physical interaction ComPPI
PDLIM5 CCDC136 25348397 N/A physical interaction ComPPI
PDLIM5 SUZ12 25348397 N/A physical interaction ComPPI
PDLIM5 RNF2 25348397 N/A physical interaction ComPPI
PDLIM5 SIRT6 25348397 N/A physical interaction ComPPI
PDLIM5 METTL6 25348397 N/A physical interaction ComPPI
PDLIM5 DNAJC8 25348397 N/A physical interaction ComPPI
PDLIM5 ARFIP2 25348397 N/A physical interaction ComPPI
PDLIM5 CAMK2G 25348397 N/A physical interaction ComPPI
PDLIM5 MED4 25348397 N/A physical interaction ComPPI
PDLIM5 SSX2IP 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PDLIM5 CEP128 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PDLIM5 XPO1 25348397 N/A physical interaction ComPPI
PDLIM5 TULP3 25348397 N/A physical interaction ComPPI
PDLIM5 PHF19 25348397 N/A physical interaction ComPPI
PDLIM5 NFATC2IP 25348397 N/A physical interaction ComPPI
PDLIM5 DENR 25348397 N/A physical interaction ComPPI
PDLIM5 EMILIN1 25348397 N/A physical interaction ComPPI
PDLIM5 ATG14 25348397 N/A physical interaction ComPPI
PDLIM5 G3BP1 25348397 N/A physical interaction ComPPI
PDLIM5 BRCA1 25348397 N/A physical interaction ComPPI
PDLIM5 TES 25348397 N/A physical interaction ComPPI
PDLIM5 ID2 16549780 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction ComPPI,IntAct
PDLIM5 ID1 16549780 24234451 25348397 N/A pull down,physical interaction ComPPI,IntAct
PKM PDLIM5 25348397 N/A physical interaction ComPPI
ID3 PDLIM5 16549780 24234451 25348397 N/A pull down,physical interaction ComPPI,IntAct
EIF4A3 PDLIM5 25348397 N/A physical interaction ComPPI
CALU PDLIM5 25348397 N/A physical interaction ComPPI
HSCB PDLIM5 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct

Source Target Pmid Interactiontype Methods Database
URS00009B3CF6 PDLIM5 27087310 direct interaction,inhibition N/A NPInter

Visualization










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