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GENE：PON2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PON2
FullNmae paraoxonase 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9205
EnsembleID ENSG00000105854
Uniprot Q15165

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PON2 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PON2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PON2 GO:0004064,GO:0005576,GO:0005886,GO:0009636,GO:0019439,GO:0042802,GO:0046872,GO:0102007

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ADRB2 PON2 23180781 23798571 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR PON2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 PON2 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
SMARCA4 PON2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PON2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PON2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
NFKBIA PON2 19401157 trascriptional regulation,stimulation inferred by curator TFlink
SREBF2 PON2 19497963 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000600E6 PON2 17242205 25416803 mrna cleavage,inhibition array technology TarBase
URS000021D7C8 PON2 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS000016FF9C PON2 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS000035CC3E PON2 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
MAD2L2 PON2 24234451 25348397 29656893 association anti tag coimmunoprecipitation ComPPI,IntAct
HYAL2 PON2 25348397 N/A physical interaction ComPPI
GRB2 PON2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RHOA PON2 25348397 N/A physical interaction ComPPI
CUL3 PON2 25348397 N/A physical interaction ComPPI
STRN3 PON2 25348397 N/A physical interaction ComPPI
CANX PON2 24234451 25348397 29568061 association pull down ComPPI,IntAct
HSPA5 PON2 25348397 N/A physical interaction ComPPI
CDC6 PON2 25348397 N/A physical interaction ComPPI
SIL1 PON2 25348397 N/A physical interaction ComPPI
SCARB1 PON2 25348397 N/A physical interaction ComPPI
HNRNPL PON2 25348397 N/A physical interaction ComPPI
PTP4A2 PON2 25348397 N/A physical interaction ComPPI
UBR2 PON2 25348397 N/A physical interaction ComPPI
RAP1A PON2 25348397 N/A physical interaction ComPPI
ATP6AP2 PON2 25348397 N/A physical interaction ComPPI
HTR2A PON2 14525934 16537434 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
PCNT PON2 25348397 N/A physical interaction ComPPI
ADRB2 PON2 25348397 N/A physical interaction ComPPI
EGFR PON2 25348397 N/A physical interaction ComPPI
ITGA6 PON2 25348397 N/A physical interaction ComPPI
ITGA4 PON2 25348397 N/A physical interaction ComPPI
INSR PON2 25348397 N/A physical interaction ComPPI
TRIM25 PON2 25348397 N/A physical interaction ComPPI
PPP2R5D PON2 25348397 N/A physical interaction ComPPI
TCF3 PON2 25348397 N/A physical interaction ComPPI
POMT2 PON2 25348397 N/A physical interaction ComPPI
B3GNT2 PON2 25348397 N/A physical interaction ComPPI
GPATCH8 PON2 25348397 N/A physical interaction ComPPI
ABCA2 PON2 25348397 N/A physical interaction ComPPI
RUVBL2 PON2 25348397 N/A physical interaction ComPPI
AMIGO1 PON2 25348397 N/A physical interaction ComPPI
SLC39A11 PON2 25348397 N/A physical interaction ComPPI
ST8SIA4 PON2 25348397 N/A physical interaction ComPPI
B4GALT1 PON2 25348397 N/A physical interaction ComPPI
M6PR PON2 25348397 N/A physical interaction ComPPI
LINGO1 PON2 25348397 N/A physical interaction ComPPI
RNF130 PON2 25348397 N/A physical interaction ComPPI
STOM PON2 25348397 N/A physical interaction ComPPI
B4GALT3 PON2 25348397 N/A physical interaction ComPPI
FBXO6 PON2 25348397 N/A physical interaction ComPPI
CTSF PON2 25348397 N/A physical interaction ComPPI
ENPP1 PON2 25348397 N/A physical interaction ComPPI
PON2 ST6GALNAC3 25348397 N/A physical interaction ComPPI
PON2 TMEM30A 25348397 N/A physical interaction ComPPI
PON2 CHST10 25348397 N/A physical interaction ComPPI
PON2 TXNDC15 25348397 N/A physical interaction ComPPI
PON2 POGLUT1 25348397 N/A physical interaction ComPPI
PON2 CACNA2D2 25348397 N/A physical interaction ComPPI
PON2 LRP11 25348397 N/A physical interaction ComPPI
PON2 NETO2 25348397 N/A physical interaction ComPPI
PON2 CACNA2D1 25348397 N/A physical interaction ComPPI
PON2 BPNT2 25348397 N/A physical interaction ComPPI
PON2 ENTPD6 25348397 N/A physical interaction ComPPI
PON2 LRIG2 25348397 N/A physical interaction ComPPI
PON2 LRIG1 25348397 N/A physical interaction ComPPI
PON2 SPPL2B 25348397 N/A physical interaction ComPPI
PON2 MR1 25348397 N/A physical interaction ComPPI
PON2 PGAP1 25348397 N/A physical interaction ComPPI
PON2 RDH11 25348397 N/A physical interaction ComPPI
PON2 MOXD1 25348397 N/A physical interaction ComPPI
PON2 UGT8 25348397 N/A physical interaction ComPPI
PON2 CHST12 25348397 N/A physical interaction ComPPI
PON2 ARSK 25348397 N/A physical interaction ComPPI
PON2 NXPH4 25348397 N/A physical interaction ComPPI
PON2 TMEM219 25348397 N/A physical interaction ComPPI
PON2 ST3GAL6 25348397 N/A physical interaction ComPPI
PON2 SAR1B 25348397 N/A physical interaction ComPPI
PON2 CHSY1 25348397 N/A physical interaction ComPPI
PON2 LMLN 25348397 N/A physical interaction ComPPI
PON2 SULF2 25348397 N/A physical interaction ComPPI
PON2 RNF167 25348397 N/A physical interaction ComPPI
PON2 RNF170 25348397 N/A physical interaction ComPPI
PON2 C1QL4 25348397 N/A physical interaction ComPPI
PON2 LRFN3 25348397 N/A physical interaction ComPPI
PON2 SMOC1 25348397 N/A physical interaction ComPPI
PON2 MAGEA10 25348397 N/A physical interaction ComPPI
PON2 ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PON2 CNNM1 25348397 N/A physical interaction ComPPI
PON2 UST 25348397 N/A physical interaction ComPPI
PON2 ART5 25348397 N/A physical interaction ComPPI
PON2 DNASE2B 25348397 N/A physical interaction ComPPI
PON2 CNTNAP3B 25348397 N/A physical interaction ComPPI
PON2 CLEC14A 25348397 N/A physical interaction ComPPI
POMGNT2 PON2 25348397 N/A physical interaction ComPPI

Source Target Pmid Interactiontype Methods Database
URS00009AF21E PON2 27087310 direct interaction,inhibition N/A NPInter

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