Gene Information gene info

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GENE：PTX3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PTX3
FullNmae pentraxin 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9692
EnsembleID ENSG00000163661
Uniprot P26022

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PTX3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PTX3 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PTX3 GO:0001550,GO:0001849,GO:0001849,GO:0001872,GO:0001878,GO:0005515,GO:0005576,GO:0005615,GO:0005615,GO:0006954,GO:0008228,GO:0030198,GO:0031012,GO:0035580,GO:0042802,GO:0044793,GO:0044869,GO:0044871,GO:0045087,GO:0045087,GO:0045429,GO:0046597,GO:0046790,GO:0050766,GO:1903016,GO:1903019,GO:1904724

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PTX3 CFH 19050261 23180781 physical association surface plasmon resonance,solid phase assay InnateDB
PTX3 FCN2 19632990 21490156 23180781 physical association surface plasmon resonance,solid phase assay InnateDB
PTX3 SELP 20208538 23180781 physical association surface plasmon resonance,solid phase assay InnateDB
FGF2 PTX3 16020751 16769728 20363749 23180781 physical association competition binding,solid phase assay InnateDB
PTX3 MBL2 21106539 23180781 physical association enzyme linked immunosorbent assay InnateDB
PTX3 FCN1 21490156 23180781 physical association surface plasmon resonance InnateDB
PTX3 FCN3 21490156 23180781 physical association surface plasmon resonance InnateDB
PTX3 C1QA 12645945 23180781 physical association solid phase assay InnateDB
PTX3 C1QC 12645945 23180781 physical association solid phase assay InnateDB
C1QA PTX3 23180781 9407058 physical association solid phase assay InnateDB
PTX3 PLG 23180781 25964372 physical association surface plasmon resonance,enzyme linked immunosorbent assay InnateDB

Source Target Pmid Interactiontype Methods Database
AR PTX3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 PTX3 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA2 PTX3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
RELA PTX3 18226221 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 PTX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PTX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
JUN PTX3 N/A trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 PTX3 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000009262D PTX3 21131358 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS000009262D PTX3 21131358 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS0000184017 PTX3 24470395 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
FGF2 PTX3 25361965 interaction type N/A PTMCode2
PTX3 FGF2 25361965 interaction type N/A PTMCode2
PTX3 C1QB 25361965 interaction type N/A PTMCode2
C1QB PTX3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
ZNF223 PTX3 25348397 N/A physical interaction ComPPI
C1QA PTX3 12645945 14525934 25348397 27898060 9407058 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
FCN1 PTX3 19632990 24234451 25348397 N/A enzyme linked immunosorbent assay ComPPI,IntAct
FCN2 PTX3 19632990 21490156 24234451 25348397 27898060 association pull down,surface plasmon resonance,enzyme linked immunosorbent assay,surface plasmon resonance array ComPPI,IntAct,OmniPath
MTNR1A PTX3 24234451 25348397 26514267 physical association two hybrid,physical interaction ComPPI,IntAct
FGF2 PTX3 14525934 16020751 20363749 22267482 24234451 25348397 physical association affinity chromatography technology,cosedimentation in solution,cross-linking study,experimental interaction detection,molecular sieving,enzyme linked immunosorbent assay,in vitro,solid phase assay ComPPI,HPRD,IntAct
CFP PTX3 19632990 24234451 25348397 association pull down ComPPI,IntAct
A2M PTX3 25348397 N/A physical interaction ComPPI
TNFAIP6 PTX3 22267482 24234451 25348397 N/A surface plasmon resonance,enzyme linked immunosorbent assay ComPPI,IntAct
PTX3 C1QB 12645945 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PTX3 C1QC 12645945 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PTX3 CFH 14525934 19050261 19632990 24234451 25348397 association experimental interaction detection,pull down,surface plasmon resonance,enzyme linked immunosorbent assay,in vitro,solid phase assay ComPPI,HPRD,IntAct
PTX3 ITIH4 21619930 25348397 27898060 N/A enzyme linked immunosorbent assay ComPPI,OmniPath
PTX3 COLEC10 25348397 N/A physical interaction ComPPI
PTX3 TRMT10B 25348397 N/A physical interaction ComPPI
PTX3 CYB5D2 25348397 N/A physical interaction ComPPI
FCN3 PTX3 19632990 24234451 25348397 N/A enzyme linked immunosorbent assay ComPPI,IntAct
ZNF224 PTX3 25348397 N/A physical interaction ComPPI
PTX3 PTX3 20363749 24234451 physical association transmission electron microscopy,cosedimentation in solution,molecular sieving,x ray scattering,electrophoretic mobility-based method IntAct
TNIP2 PTX3 24234451 30561431 association virotrap IntAct
SELP PTX3 20208538 27898060 N/A N/A OmniPath
PLG PTX3 25964372 27898060 N/A N/A OmniPath
PTX3 FGF2 16020751 16769728 20363749 27898060 N/A N/A OmniPath
PTX3 CFH 19050261 27898060 stimulant N/A OmniPath

Visualization










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