GENE:SPPL2A
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | SPPL2A |
| FullNmae | signal peptide peptidase like 2A |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:30227 |
| EnsembleID | ENSG00000138600 |
| Uniprot | Q8TCT8 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| SPPL2A | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| SPPL2A | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| SPPL2A | GO:0005515,GO:0005765,GO:0005765,GO:0005770,GO:0005886,GO:0005886,GO:0006509,GO:0010803,GO:0016020,GO:0030660,GO:0030660,GO:0031293,GO:0031293,GO:0031902,GO:0033619,GO:0033619,GO:0042500,GO:0042500,GO:0042500,GO:0042803,GO:0043231,GO:0050776,GO:0050776,GO:0070062,GO:0098553,GO:0098554 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ESR1 | SPPL2A | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| ETS1 | SPPL2A | 20019798 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA3 | SPPL2A | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXA1 | SPPL2A | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| TP63 | SPPL2A | 17521434 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | SPPL2A | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00003CCBB9 | SPPL2A | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001E0AEA | SPPL2A | 21572407 23592263 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000209F04 | SPPL2A | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C4DB5 | SPPL2A | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000007F792 | SPPL2A | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C0099 | SPPL2A | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000355E82 | SPPL2A | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000243FF1 | SPPL2A | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041FA2C | SPPL2A | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004F2EB0 | SPPL2A | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004BCD9C | SPPL2A | 21572407 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000171FEC | SPPL2A | 21572407 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000260A3A | SPPL2A | 21572407 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000038718E | SPPL2A | 21572407 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003A8BB2 | SPPL2A | 21572407 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000080D0A | SPPL2A | 21572407 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000008AA34 | SPPL2A | 21572407 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C02E4 | SPPL2A | 21572407 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000039A25B | SPPL2A | 21572407 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075B13F | SPPL2A | 21572407 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075AEA5 | SPPL2A | 21572407 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004283FE | SPPL2A | 21572407 23824327 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000118224 | SPPL2A | 21572407 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000037B2E0 | SPPL2A | 21572407 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000319E1 | SPPL2A | 21572407 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000496C56 | SPPL2A | 21572407 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000B7E30 | SPPL2A | 21572407 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000016FF9C | SPPL2A | 21572407 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000345DEB | SPPL2A | 21572407 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001D4A78 | SPPL2A | 21572407 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000427B68 | SPPL2A | 20371350 21572407 23313552 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004719AB | SPPL2A | 20371350 21572407 23313552 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000266339 | SPPL2A | 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000527B00 | SPPL2A | 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001D99D1 | SPPL2A | 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000032835F | SPPL2A | 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000553F51 | SPPL2A | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000365675 | SPPL2A | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075C4B1 | SPPL2A | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001FC26E | SPPL2A | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000D2680 | SPPL2A | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000453664 | SPPL2A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000E7139 | SPPL2A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040780F | SPPL2A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000048BA36 | SPPL2A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000008C563 | SPPL2A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041E780 | SPPL2A | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000030F801 | SPPL2A | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000411752 | SPPL2A | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00004CCA62 | SPPL2A | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00000EE7F0 | SPPL2A | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SGTA | SPPL2A | 14525934 16189514 24234451 25348397 25416956 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid | ComPPI,HPRD,IntAct |
| TFRC | SPPL2A | 23384347 24234451 25348397 | colocalization | fluorescence microscopy | ComPPI,IntAct |
| SPPL2A | NFKB1 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| SPPL2A | LGALS8 | 25348397 | N/A | physical interaction | ComPPI |
