Gene Information gene info

GENE:SPPL2A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SPPL2A
FullNmae signal peptide peptidase like 2A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:30227
EnsembleID ENSG00000138600
Uniprot Q8TCT8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SPPL2A immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SPPL2A autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SPPL2A GO:0005515,GO:0005765,GO:0005765,GO:0005770,GO:0005886,GO:0005886,GO:0006509,GO:0010803,GO:0016020,GO:0030660,GO:0030660,GO:0031293,GO:0031293,GO:0031902,GO:0033619,GO:0033619,GO:0042500,GO:0042500,GO:0042500,GO:0042803,GO:0043231,GO:0050776,GO:0050776,GO:0070062,GO:0098553,GO:0098554

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ESR1 SPPL2A 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 SPPL2A 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 SPPL2A 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 SPPL2A 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TP63 SPPL2A 17521434 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 SPPL2A 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink

Source Target Pmid Interactiontype Methods Database
URS00003CCBB9 SPPL2A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA SPPL2A 21572407 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000209F04 SPPL2A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 SPPL2A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000007F792 SPPL2A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001C0099 SPPL2A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000355E82 SPPL2A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000243FF1 SPPL2A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000041FA2C SPPL2A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 SPPL2A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004BCD9C SPPL2A 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000171FEC SPPL2A 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000260A3A SPPL2A 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000038718E SPPL2A 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00003A8BB2 SPPL2A 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000080D0A SPPL2A 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 SPPL2A 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 SPPL2A 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000039A25B SPPL2A 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000075B13F SPPL2A 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000075AEA5 SPPL2A 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE SPPL2A 21572407 23824327 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 SPPL2A 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000037B2E0 SPPL2A 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000319E1 SPPL2A 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000496C56 SPPL2A 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000B7E30 SPPL2A 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000016FF9C SPPL2A 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000345DEB SPPL2A 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00001D4A78 SPPL2A 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 SPPL2A 20371350 21572407 23313552 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004719AB SPPL2A 20371350 21572407 23313552 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000266339 SPPL2A 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000527B00 SPPL2A 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001D99D1 SPPL2A 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000032835F SPPL2A 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000553F51 SPPL2A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000365675 SPPL2A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 SPPL2A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E SPPL2A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 SPPL2A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000453664 SPPL2A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000E7139 SPPL2A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000040780F SPPL2A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000048BA36 SPPL2A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000008C563 SPPL2A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000041E780 SPPL2A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000030F801 SPPL2A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000411752 SPPL2A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00004CCA62 SPPL2A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000EE7F0 SPPL2A 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SGTA SPPL2A 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
TFRC SPPL2A 23384347 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
SPPL2A NFKB1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SPPL2A LGALS8 25348397 N/A physical interaction ComPPI

Visualization