GENE:STC2
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | STC2 |
| FullNmae | stanniocalcin 2 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:11374 |
| EnsembleID | ENSG00000113739 |
| Uniprot | O76061 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| STC2 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| STC2 | GO:0005179,GO:0005615,GO:0005615,GO:0005783,GO:0005788,GO:0005794,GO:0006874,GO:0006979,GO:0007566,GO:0010629,GO:0019899,GO:0020037,GO:0030968,GO:0033280,GO:0040015,GO:0042803,GO:0043434,GO:0046697,GO:0046885,GO:0048471,GO:0071456,GO:2001256 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | STC2 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| E2F4 | STC2 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ESR1 | STC2 | 18414489 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,chromatin immunoprecipitation assay | TFlink |
| ETS1 | STC2 | 20019798 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA1 | STC2 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | STC2 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA3 | STC2 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| HIF1A | STC2 | 18971253 19828020 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| FOXA1 | STC2 | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| RELA | STC2 | 18226221 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| CEBPA | STC2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | STC2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | STC2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | STC2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | STC2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | STC2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | STC2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000122ED0 | STC2 | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00000DDD35 | STC2 | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
| URS00002F3336 | STC2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000018CD09 | STC2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000034B6F5 | STC2 | 24855559 25416803 | mrna cleavage,inhibition | quantitative reverse transcription pcr | TarBase |
| URS000035D2F9 | STC2 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000D0BB4 | STC2 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000821E0 | STC2 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001383CF | STC2 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000007340 | STC2 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000B0E50 | STC2 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006F90B | STC2 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000012930C | STC2 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004E008F | STC2 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002FF522 | STC2 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000153377 | STC2 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000254A6 | STC2 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000029EBD | STC2 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F7766 | STC2 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000ECE9C | STC2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000044FD7 | STC2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000029D9F1 | STC2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002CEB74 | STC2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001A4ABF | STC2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003AFAD1 | STC2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000065FDF | STC2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006372A | STC2 | 25416803 26722415 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| URS0000079D48 | STC2 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000435A77 | STC2 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00000BD1DE | STC2 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000006B702 | STC2 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00004AAAFF | STC2 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00005ACA7C | STC2 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000458AD2 | STC2 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000057FDB8 | STC2 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00001481F9 | STC2 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000498DAA | STC2 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000011A030 | STC2 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000076E54 | STC2 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000202460 | STC2 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CSNK2A1 | STC2 | 22135298 | phosphorylation | N/A | PhosphoSite |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CARHSP1 | STC2 | 14525934 16169070 24234451 25348397 | physical association | physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| PPP1R8 | STC2 | 14525934 16169070 24234451 25348397 | physical association | physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| PEBP1 | STC2 | 14525934 16169070 24234451 25348397 | physical association | physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| ARRB2 | STC2 | 14525934 16169070 24234451 25348397 | physical association | physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| FBN1 | STC2 | 25348397 | N/A | pull down | ComPPI |
| TRIM25 | STC2 | 25348397 | N/A | physical interaction | ComPPI |
| ELAVL1 | STC2 | 25348397 | N/A | physical interaction | ComPPI |
| POLR2C | STC2 | 14525934 16169070 24234451 25348397 | physical association | physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| POLR3F | STC2 | 14525934 16169070 24234451 25348397 | physical association | physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| MFAP2 | STC2 | 25348397 | N/A | pull down | ComPPI |
| PTN | STC2 | 14525934 16169070 24234451 25348397 | physical association | physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| CRP | STC2 | 25348397 | N/A | physical interaction | ComPPI |
| AIFM1 | STC2 | 14525934 16169070 24234451 25348397 | physical association | physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| ADAM11 | STC2 | 14525934 16169070 24234451 25348397 | physical association | physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| LOX | STC2 | 25348397 | N/A | pull down | ComPPI |
| ARHGEF40 | STC2 | 14525934 16169070 24234451 25348397 | physical association | physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| STC2 | EIF2B3 | 14525934 16169070 24234451 25348397 | physical association | physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| STC2 | COLEC10 | 25348397 | N/A | physical interaction | ComPPI |
| STC2 | CCNJL | 25348397 | N/A | physical interaction | ComPPI |
| STC2 | FAM20C | 24234451 25348397 26091039 | phosphorylation reaction | protein kinase assay | ComPPI,IntAct |
| STC2 | BRD4 | 23746844 24234451 | association | chromatin immunoprecipitation assay | IntAct |
| CDK9 | STC2 | 23746844 24234451 | association | chromatin immunoprecipitation assay | IntAct |
| STC2 | AFF4 | 23746844 24234451 | association | chromatin immunoprecipitation assay | IntAct |
| CDK7 | STC2 | 23746844 24234451 | association | chromatin immunoprecipitation assay | IntAct |
| STC2 | MED1 | 23746844 24234451 | association | chromatin immunoprecipitation assay | IntAct |
| CDK8 | STC2 | 23746844 24234451 | association | chromatin immunoprecipitation assay | IntAct |
| STC2 | H4C1 | 23746844 24234451 | association | chromatin immunoprecipitation assay | IntAct |
| HIF1A | STC2 | 23746844 24234451 | association | chromatin immunoprecipitation assay | IntAct |
| STC2 | POLR2A | 23746844 24234451 | association | chromatin immunoprecipitation assay | IntAct |
| ANXA2 | STC2 | 24234451 30021884 | physical association | cross-linking study | IntAct |
| CSNK2A1 | STC2 | 10947959 27898060 | N/A | N/A | OmniPath |
