GENE：TBL1X
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | TBL1X |
| FullNmae | transducin beta like 1 X-linked |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:11585 |
| EnsembleID | ENSG00000101849 |
| Uniprot | O60907 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| TBL1X | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| TBL1X | GO:0000118,GO:0000118,GO:0000122,GO:0000976,GO:0003714,GO:0003714,GO:0003714,GO:0005515,GO:0005634,GO:0005654,GO:0006357,GO:0006508,GO:0007605,GO:0017053,GO:0042393,GO:0043161,GO:0045893,GO:0045944,GO:0050821,GO:0072686,GO:0090263 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| TBL1X | hsa:6907 | path:hsa04310 | Wnt signaling pathway - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| HDAC3 | TBL1X | 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 26192618 6357187 8871614 | interaction type | N/A | ACSN |
| NCOR1 | TBL1X | 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 26192618 6357187 8871614 | interaction type | N/A | ACSN |
| TBL1X | TBL1XR1 | 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 26192618 6357187 8871614 | interaction type | N/A | ACSN |
| PPARG | TBL1X | 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 26192618 6357187 8871614 | interaction type | N/A | ACSN |
| TBL1X | NOS2 | 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 26192618 6357187 8871614 | interaction type | N/A | ACSN |
| TBL1X | CXCL10 | 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 26192618 6357187 8871614 | interaction type | N/A | ACSN |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | TBL1X | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | TBL1X | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | TBL1X | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | TBL1X | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | TBL1X | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| PRDM14 | TBL1X | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | TBL1X | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | TBL1X | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | TBL1X | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | TBL1X | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | TBL1X | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | TBL1X | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | TBL1X | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | TBL1X | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | TBL1X | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | TBL1X | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | TBL1X | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | TBL1X | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | TBL1X | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000237AF9 | TBL1X | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00000F31F4 | TBL1X | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00000B59A2 | TBL1X | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00004214BB | TBL1X | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003A5E54 | TBL1X | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003003B4 | TBL1X | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004407DC | TBL1X | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000042619A | TBL1X | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| GPS2 | TBL1X | 25361965 | interaction type | N/A | PTMCode2 |
| TBL1X | GPS2 | 25361965 | interaction type | N/A | PTMCode2 |
| HDAC3 | TBL1X | 25361965 | interaction type | N/A | PTMCode2 |
| TBL1X | HDAC3 | 25361965 | interaction type | N/A | PTMCode2 |
| TBL1X | HDAC5 | 25361965 | interaction type | N/A | PTMCode2 |
| HDAC5 | TBL1X | 25361965 | interaction type | N/A | PTMCode2 |
| TBL1X | SKP1 | 25361965 | interaction type | N/A | PTMCode2 |
| SKP1 | TBL1X | 25361965 | interaction type | N/A | PTMCode2 |
| TBL1X | CTBP1 | 25361965 | interaction type | N/A | PTMCode2 |
| CTBP1 | TBL1X | 25361965 | interaction type | N/A | PTMCode2 |
| TBL1X | CORO2A | 25361965 | interaction type | N/A | PTMCode2 |
| CORO2A | TBL1X | 25361965 | interaction type | N/A | PTMCode2 |
| TBL1X | CTNNB1 | 25361965 | interaction type | N/A | PTMCode2 |
| CTNNB1 | TBL1X | 25361965 | interaction type | N/A | PTMCode2 |
| TBL1X | SIAH1 | 25361965 | interaction type | N/A | PTMCode2 |
| SIAH1 | TBL1X | 25361965 | interaction type | N/A | PTMCode2 |
| TBL1X | CACYBP | 25361965 | interaction type | N/A | PTMCode2 |
| CACYBP | TBL1X | 25361965 | interaction type | N/A | PTMCode2 |
| TBL1X | TBL1X | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| UBE2I | TBL1X | 25348397 | N/A | physical interaction | ComPPI |
| EMD | TBL1X | 25348397 | N/A | physical interaction | ComPPI |
| SKP1 | TBL1X | 11389839 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD |
| UBE2D1 | TBL1X | 25348397 | N/A | physical interaction | ComPPI |
| UBE2E3 | TBL1X | 25348397 | N/A | physical interaction | ComPPI |
| EGLN3 | TBL1X | 24234451 25348397 26972000 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| H4C1 | TBL1X | 12628926 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| KHDRBS1 | TBL1X | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| SMARCD1 | TBL1X | 25348397 | N/A | physical interaction | ComPPI |
| HDAC3 | TBL1X | 10809664 10944117 11931768 14525934 16980585 21258344 23752268 24234451 25348397 | association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD,IntAct |
| CTBP1 | TBL1X | 25348397 | N/A | physical interaction | ComPPI |
| SIAH1 | TBL1X | 25348397 | N/A | physical interaction | ComPPI |
| THRA | TBL1X | 25348397 | N/A | physical interaction | ComPPI |
| THRB | TBL1X | 25348397 | N/A | physical interaction | ComPPI |
| NCOR2 | TBL1X | 25348397 | N/A | two hybrid,fluorescence polarization spectroscopy,pull down,physical interaction,physical interaction,in vitro,in vivo | ComPPI |
| NCOR1 | TBL1X | 12628926 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| SERPINB2 | TBL1X | 25348397 | N/A | physical interaction | ComPPI |
| SIN3A | TBL1X | 25348397 | N/A | physical interaction | ComPPI |
| CACYBP | TBL1X | 24234451 25241761 25348397 | physical association | physical interaction,proximity ligation assay | ComPPI,IntAct |
| HNRNPL | TBL1X | 25348397 | N/A | physical interaction | ComPPI |
| DLX3 | TBL1X | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| RELA | TBL1X | 25348397 | N/A | physical interaction | ComPPI |
| H2BC21 | TBL1X | 12628926 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| XPO1 | TBL1X | 25348397 | N/A | physical interaction | ComPPI |
| H2AC18 | TBL1X | 25348397 | N/A | physical interaction | ComPPI |
| SMARCB1 | TBL1X | 25348397 | N/A | physical interaction | ComPPI |
| HUWE1 | TBL1X | 25348397 | N/A | physical interaction | ComPPI |
| CDC34 | TBL1X | 25348397 | N/A | physical interaction | ComPPI |
| H3C15 | TBL1X | 25348397 | N/A | physical interaction | ComPPI |
| CTNNB1 | TBL1X | 11389839 14525934 24234451 25241761 25348397 | physical association | two hybrid,experimental interaction detection,physical interaction,in vitro,proximity ligation assay,two hybrid | ComPPI,HPRD,IntAct |
| GPS2 | TBL1X | 11931768 14525934 21240272 24943844 25348397 26070566 26186194 27898060 | N/A | experimental interaction detection,fluorescence polarization spectroscopy,pull down,physical interaction,in vitro | ComPPI,HPRD,OmniPath |
| TAB2 | TBL1X | 25348397 | N/A | physical interaction | ComPPI |
| TBL1X | CORO2A | 12628926 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| TBL1X | HDAC5 | 23752268 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| TBL1X | HR | 25348397 | N/A | physical interaction | ComPPI |
| TBL1X | ELAVL1 | 25348397 | N/A | physical interaction | ComPPI |
| TBL1X | NRDC | 25348397 | N/A | physical interaction | ComPPI |
| TBL1X | TERF1 | 21044950 24234451 25348397 | physical association | physical interaction,bimolecular fluorescence complementation | ComPPI,IntAct |
| TBL1X | TINF2 | 21044950 24234451 25348397 | physical association | pull down,physical interaction,bimolecular fluorescence complementation | ComPPI,IntAct |
| TBL1X | GID8 | 25348397 | N/A | physical interaction | ComPPI |
| TBL1X | SNRNP40 | 25348397 | N/A | physical interaction | ComPPI |
| TBL1X | HDAC7 | 23752268 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| TBL1X | HP | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| TBL1X | DNAJB4 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| TBL1X | FKBP6 | 25348397 | N/A | physical interaction | ComPPI |
| TBL1X | TSC22D4 | 25348397 | N/A | physical interaction | ComPPI |
| TBL1X | SMARCD2 | 25348397 | N/A | physical interaction | ComPPI |
| TBL1X | SMARCD3 | 25348397 | N/A | physical interaction | ComPPI |
| TBL1X | FOXK2 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| TBL1X | NANOGP8 | 25348397 | N/A | physical interaction | ComPPI |
| TBL1X | NANOG | 25348397 | N/A | physical interaction | ComPPI |
| TBL1X | TBL1Y | 25348397 | N/A | physical interaction | ComPPI |
| TBL1X | MKX | 25348397 | N/A | physical interaction | ComPPI |
| TBL1X | C6ORF141 | 25348397 | N/A | physical interaction | ComPPI |
| TBL1X | IL17RA | 25348397 | N/A | physical interaction | ComPPI |
| TBL1X | LRRC36 | 25348397 | N/A | physical interaction | ComPPI |
| TBL1X | TKT | 25348397 | N/A | physical interaction | ComPPI |
| TBL1X | WDR59 | 25348397 | N/A | physical interaction | ComPPI |
| TBL1X | KLHDC3 | 25348397 | N/A | physical interaction | ComPPI |
| TBL1X | HAO2 | 25348397 | N/A | physical interaction | ComPPI |
| TBL1X | USP44 | 25348397 | N/A | physical interaction | ComPPI |
| TBL1X | TRIM25 | 25348397 | N/A | physical interaction | ComPPI |
| TBL1X | ARL3 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| TBL1XR1 | TBL1X | 14525934 15601853 21258344 24234451 25348397 | association | anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD,IntAct |