GENE:UBR2
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | UBR2 |
FullNmae | ubiquitin protein ligase E3 component n-recognin 2 |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:21289 |
EnsembleID | ENSG00000024048 |
Uniprot | Q8IWV8 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
UBR2 | pyroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
UBR2 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
UBR2 | GO:0000151,GO:0000785,GO:0005515,GO:0005634,GO:0005737,GO:0005829,GO:0007131,GO:0007140,GO:0007141,GO:0007283,GO:0008270,GO:0010526,GO:0016567,GO:0016567,GO:0031507,GO:0032007,GO:0061630,GO:0070728,GO:0071233,GO:0071596,GO:0140852 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
AR | UBR2 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
ETS1 | UBR2 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
GATA2 | UBR2 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
YBX1 | UBR2 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
FOXP3 | UBR2 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
SMARCA4 | UBR2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | UBR2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | UBR2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F1 | UBR2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | UBR2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXA1 | UBR2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXP1 | UBR2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | UBR2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | UBR2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
MITF | UBR2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
SPI1 | UBR2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
ZNF263 | UBR2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
UBXN2B | UBR2 | 25348397 | N/A | physical interaction | ComPPI |
CCDC130 | UBR2 | 25348397 | N/A | physical interaction | ComPPI |
SPINK2 | UBR2 | 25348397 | N/A | physical interaction | ComPPI |
H2BC4 | UBR2 | 25348397 | N/A | physical interaction | ComPPI |
PAK5 | UBR2 | 25348397 | N/A | physical interaction | ComPPI |
PAM | UBR2 | 25348397 | N/A | physical interaction | ComPPI |
UBC | UBR2 | 25348397 | N/A | physical interaction | ComPPI |
FAF1 | UBR2 | 18775313 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
BAG6 | UBR2 | 25348397 | N/A | physical interaction | ComPPI |
TIRAP | UBR2 | 21903422 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
MYC | UBR2 | 17314511 24234451 25348397 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
SIL1 | UBR2 | 25348397 | N/A | physical interaction | ComPPI |
HNRNPL | UBR2 | 25348397 | N/A | physical interaction | ComPPI |
PDP2 | UBR2 | 25348397 | N/A | physical interaction | ComPPI |
PARD6B | UBR2 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
UBE2B | UBR2 | 14525934 14585983 20080676 25348397 25582440 27898060 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD,OmniPath |
UBR2 | HNRNPA1 | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | H2AC20 | 20080676 22616001 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
UBR2 | UBXN7 | 18775313 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
UBR2 | FAF2 | 18775313 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
UBR2 | UBXN1 | 18775313 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
UBR2 | UBE2Z | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | H2BC11 | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | RECQL4 | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | UBE2H | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | GCFC2 | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | NXPH2 | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | NUDT6 | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | MRM1 | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | MYZAP | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | POLR2M | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | SOD2 | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | PLEKHO2 | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | PLXDC2 | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | TEX33 | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | PON2 | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | UBE2A | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | CLCC1 | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | METTL15 | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | EPPK1 | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | EPHA7 | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | SNX18 | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | NDUFS3 | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | PSMC2 | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | NES | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
UBR2 | MRPL50 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
UBR2 | SGO1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
UBR2 | FOXJ3 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
UBR2 | DUSP26 | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | NRP1 | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | HS3ST2 | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | INSL5 | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | SMOC1 | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | HYAL1 | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | GFAP | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | RGS8 | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | CROCC | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | ASB6 | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | CRHBP | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | HEPACAM2 | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | PNLIPRP1 | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | METTL2A | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | BRCA1 | 25348397 | N/A | physical interaction | ComPPI |
ALDH18A1 | UBR2 | 25348397 | N/A | physical interaction | ComPPI |
UBR2 | DSN1 | 23408894 23636741 27898060 | N/A | N/A | OmniPath |
UBR2 | RECQL4 | 15317757 20096650 27898060 | stimulant | N/A | OmniPath |
TIRAP | UBR2 | 21903422 27898060 | N/A | N/A | OmniPath |