Gene Information gene info

GENE:UBR2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol UBR2
FullNmae ubiquitin protein ligase E3 component n-recognin 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:21289
EnsembleID ENSG00000024048
Uniprot Q8IWV8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
UBR2 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
UBR2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
UBR2 GO:0000151,GO:0000785,GO:0005515,GO:0005634,GO:0005737,GO:0005829,GO:0007131,GO:0007140,GO:0007141,GO:0007283,GO:0008270,GO:0010526,GO:0016567,GO:0016567,GO:0031507,GO:0032007,GO:0061630,GO:0070728,GO:0071233,GO:0071596,GO:0140852

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TIRAP UBR2 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR UBR2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 UBR2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 UBR2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 UBR2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 UBR2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 UBR2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA UBR2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF UBR2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 UBR2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 UBR2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 UBR2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 UBR2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS UBR2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A UBR2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF UBR2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 UBR2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 UBR2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 UBR2 18185580 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
UBXN2B UBR2 25348397 N/A physical interaction ComPPI
CCDC130 UBR2 25348397 N/A physical interaction ComPPI
SPINK2 UBR2 25348397 N/A physical interaction ComPPI
H2BC4 UBR2 25348397 N/A physical interaction ComPPI
PAK5 UBR2 25348397 N/A physical interaction ComPPI
PAM UBR2 25348397 N/A physical interaction ComPPI
UBC UBR2 25348397 N/A physical interaction ComPPI
FAF1 UBR2 18775313 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BAG6 UBR2 25348397 N/A physical interaction ComPPI
TIRAP UBR2 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYC UBR2 17314511 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SIL1 UBR2 25348397 N/A physical interaction ComPPI
HNRNPL UBR2 25348397 N/A physical interaction ComPPI
PDP2 UBR2 25348397 N/A physical interaction ComPPI
PARD6B UBR2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBE2B UBR2 14525934 14585983 20080676 25348397 25582440 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
UBR2 HNRNPA1 25348397 N/A physical interaction ComPPI
UBR2 H2AC20 20080676 22616001 25348397 27898060 N/A physical interaction ComPPI,OmniPath
UBR2 UBXN7 18775313 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBR2 FAF2 18775313 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBR2 UBXN1 18775313 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBR2 UBE2Z 25348397 N/A physical interaction ComPPI
UBR2 H2BC11 25348397 N/A physical interaction ComPPI
UBR2 RECQL4 25348397 N/A physical interaction ComPPI
UBR2 UBE2H 25348397 N/A physical interaction ComPPI
UBR2 GCFC2 25348397 N/A physical interaction ComPPI
UBR2 NXPH2 25348397 N/A physical interaction ComPPI
UBR2 NUDT6 25348397 N/A physical interaction ComPPI
UBR2 MRM1 25348397 N/A physical interaction ComPPI
UBR2 MYZAP 25348397 N/A physical interaction ComPPI
UBR2 POLR2M 25348397 N/A physical interaction ComPPI
UBR2 SOD2 25348397 N/A physical interaction ComPPI
UBR2 PLEKHO2 25348397 N/A physical interaction ComPPI
UBR2 PLXDC2 25348397 N/A physical interaction ComPPI
UBR2 TEX33 25348397 N/A physical interaction ComPPI
UBR2 PON2 25348397 N/A physical interaction ComPPI
UBR2 UBE2A 25348397 N/A physical interaction ComPPI
UBR2 CLCC1 25348397 N/A physical interaction ComPPI
UBR2 METTL15 25348397 N/A physical interaction ComPPI
UBR2 EPPK1 25348397 N/A physical interaction ComPPI
UBR2 EPHA7 25348397 N/A physical interaction ComPPI
UBR2 SNX18 25348397 N/A physical interaction ComPPI
UBR2 NDUFS3 25348397 N/A physical interaction ComPPI
UBR2 PSMC2 25348397 N/A physical interaction ComPPI
UBR2 NES 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBR2 MRPL50 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBR2 SGO1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBR2 FOXJ3 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
UBR2 DUSP26 25348397 N/A physical interaction ComPPI
UBR2 NRP1 25348397 N/A physical interaction ComPPI
UBR2 HS3ST2 25348397 N/A physical interaction ComPPI
UBR2 INSL5 25348397 N/A physical interaction ComPPI
UBR2 SMOC1 25348397 N/A physical interaction ComPPI
UBR2 HYAL1 25348397 N/A physical interaction ComPPI
UBR2 GFAP 25348397 N/A physical interaction ComPPI
UBR2 RGS8 25348397 N/A physical interaction ComPPI
UBR2 CROCC 25348397 N/A physical interaction ComPPI
UBR2 ASB6 25348397 N/A physical interaction ComPPI
UBR2 CRHBP 25348397 N/A physical interaction ComPPI
UBR2 HEPACAM2 25348397 N/A physical interaction ComPPI
UBR2 PNLIPRP1 25348397 N/A physical interaction ComPPI
UBR2 METTL2A 25348397 N/A physical interaction ComPPI
UBR2 BRCA1 25348397 N/A physical interaction ComPPI
ALDH18A1 UBR2 25348397 N/A physical interaction ComPPI
UBR2 DSN1 23408894 23636741 27898060 N/A N/A OmniPath
UBR2 RECQL4 15317757 20096650 27898060 stimulant N/A OmniPath
TIRAP UBR2 21903422 27898060 N/A N/A OmniPath

Visualization