Gene Information gene info

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GENE：YBX3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol YBX3
FullNmae Y-box binding protein 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2428
EnsembleID ENSG00000060138
Uniprot P16989

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
YBX3 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
YBX3 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
YBX3 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
YBX3 GO:0000122,GO:0000977,GO:0001701,GO:0003676,GO:0003723,GO:0003730,GO:0005515,GO:0005634,GO:0005634,GO:0005737,GO:0005829,GO:0005923,GO:0006915,GO:0007283,GO:0008584,GO:0009566,GO:0010468,GO:0031267,GO:0035234,GO:0045202,GO:0046622,GO:0048471,GO:0048642,GO:0060546,GO:0070935,GO:0071356,GO:0071474,GO:1902219,GO:1905538,GO:2000242,GO:2000767

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
YBX3 hsa:8531 path:hsa04530 Tight junction - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
YBX3 HBG2 20636440 23180781 physical association anti tag coimmunoprecipitation InnateDB
EZH2 YBX3 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
SUZ12 YBX3 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
RNF2 YBX3 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
BMI1 YBX3 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR YBX3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 YBX3 11799066 18971253 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
ETS1 YBX3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
MYC YBX3 12747840 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 YBX3 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 YBX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA YBX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF YBX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 YBX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 YBX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS YBX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 YBX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 YBX3 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000065D58 YBX3 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000013DD8 YBX3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000AA464 YBX3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001A405B YBX3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000035CC3E YBX3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002B2B5C YBX3 23505378 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,northern blot,rna immunoprecipitation,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
CHEK1 YBX3 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
SNW1 YBX3 20467437 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CUL5 YBX3 25348397 N/A physical interaction ComPPI
CBX8 YBX3 21282530 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
IFIT3 YBX3 21642987 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NPM1 YBX3 25348397 N/A physical interaction ComPPI
NFYB YBX3 14525934 25348397 27898060 9442396 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
EIF2B2 YBX3 25348397 N/A physical interaction ComPPI
GABARAPL2 YBX3 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
BMI1 YBX3 25348397 N/A physical interaction ComPPI
DCUN1D1 YBX3 25348397 N/A physical interaction ComPPI
MAP1LC3B YBX3 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
COX5A YBX3 25348397 N/A physical interaction ComPPI
INO80B YBX3 25348397 N/A physical interaction ComPPI
RRS1 YBX3 25348397 N/A physical interaction ComPPI
MAPK1 YBX3 14525934 16198352 24234451 25348397 phosphorylation reaction experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
EZH2 YBX3 25348397 N/A physical interaction ComPPI
VEGFA YBX3 14525934 16198352 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
ATR YBX3 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARAF YBX3 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JUN YBX3 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
DHX9 YBX3 25348397 N/A physical interaction ComPPI
COPS5 YBX3 25348397 N/A physical interaction ComPPI
USP7 YBX3 25348397 N/A physical interaction ComPPI
NELFB YBX3 25348397 N/A physical interaction ComPPI
BLK YBX3 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF5B YBX3 25348397 N/A physical interaction ComPPI
PAXIP1 YBX3 25348397 N/A physical interaction ComPPI
GSK3B YBX3 14525934 16198352 24234451 25348397 phosphorylation reaction experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
CUL3 YBX3 25348397 N/A physical interaction ComPPI
YBX1 YBX3 23986595 24234451 25348397 25497084 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct
E4F1 YBX3 25348397 N/A physical interaction ComPPI
PPP1CA YBX3 24234451 25348397 25593058 colocalization,association,physical association anti bait coimmunoprecipitation,fluorescence microscopy ComPPI,IntAct
HNRNPU YBX3 25348397 N/A physical interaction ComPPI
RALA YBX3 14525934 15592429 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
C1QBP YBX3 25348397 N/A physical interaction ComPPI
TRIM29 YBX3 25348397 N/A physical interaction ComPPI
ABCB7 YBX3 25348397 N/A physical interaction ComPPI
SRPK1 YBX3 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NEDD8 YBX3 25348397 N/A physical interaction ComPPI
CUL2 YBX3 25348397 N/A physical interaction ComPPI
CUL4B YBX3 25348397 N/A physical interaction ComPPI
ARRB2 YBX3 17620599 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK2 YBX3 25348397 N/A physical interaction ComPPI
CUL1 YBX3 25348397 N/A physical interaction ComPPI
RNF2 YBX3 25348397 N/A physical interaction ComPPI
YBX3 PCBP2 14525934 25348397 8871564 N/A two hybrid,two hybrid ComPPI,HPRD
YBX3 RRP1B 25348397 N/A physical interaction,tandem affinity purification ComPPI
YBX3 MEPCE 25348397 N/A physical interaction ComPPI
YBX3 TJP1 25348397 N/A physical interaction ComPPI
YBX3 DOT1L 25348397 N/A physical interaction ComPPI
YBX3 HAUS6 19369198 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YBX3 ELAVL1 25348397 N/A physical interaction ComPPI
YBX3 CAND1 25348397 N/A physical interaction ComPPI
YBX3 NDUFB10 25348397 N/A physical interaction ComPPI
YBX3 ESR1 21182205 24234451 25348397 association affinity chromatography technology,physical interaction ComPPI,IntAct
YBX3 MAGOH 23084401 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YBX3 IFIT2 21642987 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YBX3 IL7R 25348397 N/A physical interaction ComPPI
YBX3 PAN2 25348397 N/A physical interaction ComPPI
YBX3 IGSF8 25348397 N/A physical interaction ComPPI
YBX3 ICAM1 25348397 N/A physical interaction ComPPI
YBX3 HDAC11 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YBX3 SRPK3 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
YBX3 TARDBP 25348397 N/A physical interaction ComPPI
YBX3 PRKN 25348397 N/A physical interaction ComPPI
YBX3 ABCF1 25348397 N/A physical interaction ComPPI
YBX3 RTCB 25348397 N/A physical interaction ComPPI
YBX3 CSRP1 25348397 N/A physical interaction ComPPI
YBX3 DDX1 25348397 N/A physical interaction ComPPI
YBX3 EIF2B3 25348397 N/A physical interaction ComPPI
YBX3 MACF1 25348397 N/A physical interaction ComPPI
YBX3 IGF2BP3 25348397 N/A physical interaction ComPPI
YBX3 MAP7 25348397 N/A physical interaction ComPPI
YBX3 MRE11 25348397 N/A physical interaction ComPPI
YBX3 NMT1 25348397 N/A physical interaction ComPPI
YBX3 PTBP1 25348397 N/A physical interaction ComPPI
YBX3 RFC4 25348397 N/A physical interaction ComPPI
YBX3 CEP250 25348397 N/A physical interaction ComPPI
YBX3 CEP76 25348397 N/A physical interaction ComPPI
YBX3 SUZ12 25348397 N/A physical interaction ComPPI
YBX3 MAST3 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YBX3 PXK 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YBX3 HNRNPA1 25348397 N/A physical interaction ComPPI
YBX3 ATP6V0D1 25348397 N/A physical interaction ComPPI
YBX3 NDUFA9 25348397 N/A physical interaction ComPPI
YBX3 MTREX 25348397 N/A physical interaction ComPPI
YBX3 SRPK2 25348397 N/A physical interaction ComPPI
YBX3 SLAIN2 25348397 N/A physical interaction ComPPI
YBX3 UBA5 25348397 N/A physical interaction ComPPI
YBX3 NLRP3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YBX3 NEDD1 25348397 N/A physical interaction ComPPI
YBX3 RC3H1 25348397 N/A physical interaction ComPPI
YBX3 CENATAC 25348397 N/A physical interaction ComPPI
YBX3 CDK5 25348397 N/A physical interaction ComPPI
YBX3 CDK4 25348397 N/A physical interaction ComPPI
YBX3 ZNF746 25348397 N/A physical interaction ComPPI
YBX3 RPL6 25348397 N/A physical interaction ComPPI
YBX3 ZC3HAV1 25348397 N/A physical interaction ComPPI
YBX3 PPAN 25348397 N/A physical interaction ComPPI
YBX3 BHLHA15 25348397 N/A physical interaction ComPPI
YBX3 SART3 25348397 N/A physical interaction ComPPI
YBX3 H2AX 25348397 N/A physical interaction ComPPI
YBX3 CYLD 25348397 N/A physical interaction ComPPI
YBX3 TRIM25 25348397 N/A physical interaction ComPPI
YBX3 G3BP1 25348397 N/A physical interaction ComPPI
YBX3 GABARAP 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
YBX3 IGF2BP1 19029303 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
YBX3 ZC3H18 24234451 25348397 29298432 association anti tag coimmunoprecipitation ComPPI,IntAct
YBX3 NBEAL2 24234451 25348397 29187380 association tandem affinity purification ComPPI,IntAct
MAP3K14 YBX3 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
H3C1 YBX3 25348397 N/A physical interaction ComPPI
ILF2 YBX3 25348397 N/A physical interaction ComPPI
SRRM1 YBX3 25348397 N/A physical interaction ComPPI
EIF4A3 YBX3 23084401 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RTRAF YBX3 25348397 N/A physical interaction ComPPI
PELO YBX3 25348397 N/A physical interaction ComPPI
MKI67 YBX3 24234451 26949251 association anti tag coimmunoprecipitation IntAct
SMARCB1 YBX3 24234451 30108113 association pull down,proximity-dependent biotin identification IntAct

Visualization










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