GENE:ZFP36L2
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | ZFP36L2 |
| FullNmae | ZFP36 ring finger protein like 2 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:1108 |
| EnsembleID | ENSG00000152518 |
| Uniprot | P47974 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| ZFP36L2 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| ZFP36L2 | GO:0000288,GO:0003723,GO:0005515,GO:0005634,GO:0005737,GO:0006402,GO:0006402,GO:0009611,GO:0030097,GO:0033077,GO:0035019,GO:0035925,GO:0043488,GO:0043488,GO:0044344,GO:0045577,GO:0045599,GO:0046872,GO:0048103,GO:0060216,GO:0061158,GO:0061158,GO:0070371,GO:0071356,GO:0071364,GO:0071385,GO:0071560,GO:0097011,GO:1900153,GO:1901991,GO:1990904,GO:2000737 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| ZFP36L2 | hsa:678 | path:hsa04218 | Cellular senescence - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | ZFP36L2 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ESR1 | ZFP36L2 | 18414489 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | ZFP36L2 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | ZFP36L2 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | ZFP36L2 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXA1 | ZFP36L2 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | ZFP36L2 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| CEBPA | ZFP36L2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | ZFP36L2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | ZFP36L2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | ZFP36L2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | ZFP36L2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | ZFP36L2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | ZFP36L2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| VDR | ZFP36L2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | ZFP36L2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MYC | ZFP36L2 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00004505E4 | ZFP36L2 | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
| URS00000ED600 | ZFP36L2 | 20215506 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00002B7450 | ZFP36L2 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000021D7C8 | ZFP36L2 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000035CC3E | ZFP36L2 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000427B68 | ZFP36L2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001B341F | ZFP36L2 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000330617 | ZFP36L2 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003804D8 | ZFP36L2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004F4657 | ZFP36L2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075AB0E | ZFP36L2 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000202460 | ZFP36L2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000243FF1 | ZFP36L2 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000CBE63 | ZFP36L2 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000B0E50 | ZFP36L2 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001E0AEA | ZFP36L2 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002E92A8 | ZFP36L2 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000236310 | ZFP36L2 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000018C928 | ZFP36L2 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001067D1 | ZFP36L2 | 25416803 28735896 | mrna cleavage,inhibition | clip | TarBase |
| URS00000913AC | ZFP36L2 | 25416803 28735896 | mrna cleavage,inhibition | clip | TarBase |
| URS00005194EC | ZFP36L2 | 25416803 28735896 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CBY1 | ZFP36L2 | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
| CUL3 | ZFP36L2 | 25348397 | N/A | physical interaction | ComPPI |
| YWHAB | ZFP36L2 | 24234451 24255178 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| XPO1 | ZFP36L2 | 25348397 | N/A | physical interaction | ComPPI |
| GEMIN5 | ZFP36L2 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| YWHAH | ZFP36L2 | 17979178 24234451 25348397 | association | tandem affinity purification | ComPPI,IntAct |
| YWHAE | ZFP36L2 | 25348397 | N/A | physical interaction | ComPPI |
| SF1 | ZFP36L2 | 24234451 25348397 26420826 | physical association | two hybrid fragment pooling approach | ComPPI,IntAct |
| HIF1AN | ZFP36L2 | 25348397 | N/A | physical interaction | ComPPI |
| SMC6 | ZFP36L2 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
