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GENE：TUBA1B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TUBA1B
FullNmae tubulin alpha 1b
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18809
EnsembleID ENSG00000123416
Uniprot P68363

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TUBA1B autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TUBA1B autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TUBA1B GO:0000226,GO:0000226,GO:0000278,GO:0003725,GO:0003924,GO:0005198,GO:0005200,GO:0005200,GO:0005515,GO:0005525,GO:0005525,GO:0005737,GO:0005874,GO:0005874,GO:0005874,GO:0005881,GO:0007017,GO:0015630,GO:0030705,GO:0031625,GO:0051301,GO:0071353

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TUBA1B hsa:10376 path:hsa04145 Phagosome - Homo sapiens (human)
TUBA1B hsa:10376 path:hsa04210 Apoptosis - Homo sapiens (human)
TUBA1B hsa:10376 path:hsa04530 Tight junction - Homo sapiens (human)
TUBA1B hsa:10376 path:hsa04540 Gap junction - Homo sapiens (human)
TUBA1B hsa:10376 path:hsa04814 Motor proteins - Homo sapiens (human)
TUBA1B hsa:10376 path:hsa05010 Alzheimer disease - Homo sapiens (human)
TUBA1B hsa:10376 path:hsa05012 Parkinson disease - Homo sapiens (human)
TUBA1B hsa:10376 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
TUBA1B hsa:10376 path:hsa05016 Huntington disease - Homo sapiens (human)
TUBA1B hsa:10376 path:hsa05020 Prion disease - Homo sapiens (human)
TUBA1B hsa:10376 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
TUBA1B hsa:10376 path:hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human)
TUBA1B hsa:10376 path:hsa05132 Salmonella infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
NDUFAF1 TUBA1B 17344420 23180781 physical association tandem affinity purification InnateDB
STARD13 TUBA1B 14697242 23180781 physical association anti tag coimmunoprecipitation,two hybrid InnateDB
GZMM TUBA1B 18523284 23180781 protein cleavage protease assay InnateDB
IL7R TUBA1B 20167604 23180781 physical association anti tag coimmunoprecipitation InnateDB
MYD88 TUBA1B 21827211 23180781 physical association pull down InnateDB
YWHAQ TUBA1B 21827211 23180781 physical association pull down InnateDB
EZH2 TUBA1B 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
EED TUBA1B 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
RNF2 TUBA1B 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
ADRB2 TUBA1B 23180781 23798571 physical association anti tag coimmunoprecipitation InnateDB
TUBA1B UBB 23180781 24816145 ubiquitination reaction ubiquitinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 TUBA1B 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 TUBA1B 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 TUBA1B 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PPARA TUBA1B 23029400 trascriptional regulation,stimulation inferred by curator TFlink
RORA TUBA1B 23029400 trascriptional regulation,stimulation inferred by curator TFlink
SMARCA4 TUBA1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TUBA1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 TUBA1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 TUBA1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TUBA1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TUBA1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 TUBA1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR TUBA1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AA464 TUBA1B 21512034 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000512C88 TUBA1B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000070B1D TUBA1B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000EC1BE TUBA1B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000017EA6A TUBA1B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C3AC1 TUBA1B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000821E0 TUBA1B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004505E4 TUBA1B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000013DD8 TUBA1B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 TUBA1B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE TUBA1B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005481D TUBA1B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD TUBA1B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001CC379 TUBA1B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004AC389 TUBA1B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000008F0CF TUBA1B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000065D58 TUBA1B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000000B1C9 TUBA1B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 TUBA1B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003ACE11 TUBA1B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002F5FEE TUBA1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000308E4D TUBA1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000053B1E8 TUBA1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000E1E9E TUBA1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MAP3K7 TUBA1B 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
SNW1 TUBA1B 25348397 N/A physical interaction ComPPI
CDC5L TUBA1B 25348397 N/A physical interaction ComPPI
UBASH3B TUBA1B 25348397 N/A physical interaction ComPPI
TUBB TUBA1B 25348397 N/A physical interaction ComPPI
UBL4A TUBA1B 25348397 N/A physical interaction ComPPI
U2AF1L5 TUBA1B 25348397 N/A physical interaction ComPPI
KEAP1 TUBA1B 25348397 N/A physical interaction ComPPI
LTV1 TUBA1B 25348397 N/A physical interaction ComPPI
KATNAL1 TUBA1B 24234451 25348397 26929214 association tandem affinity purification ComPPI,IntAct
ERRFI1 TUBA1B 25348397 N/A physical interaction ComPPI
EZH2 TUBA1B 25348397 N/A physical interaction ComPPI
SP1 TUBA1B 25348397 N/A physical interaction ComPPI
PIK3R1 TUBA1B 14525934 25348397 7592789 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CD81 TUBA1B 25348397 N/A physical interaction ComPPI
SHC1 TUBA1B 25348397 N/A physical interaction ComPPI
GRB2 TUBA1B 12577067 24234451 25348397 association pull down ComPPI,IntAct
JUN TUBA1B 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
SMAD2 TUBA1B 20195357 24234451 25348397 physical association display technology,physical interaction ComPPI,IntAct
SF3B1 TUBA1B 25348397 N/A physical interaction ComPPI
ZAP70 TUBA1B 25348397 N/A physical interaction ComPPI
INPPL1 TUBA1B 25348397 N/A physical interaction ComPPI
PSMA3 TUBA1B 25348397 N/A physical interaction ComPPI
SIAH1 TUBA1B 11146551 14525934 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
RBX1 TUBA1B 25348397 N/A physical interaction ComPPI
YWHAZ TUBA1B 15161933 24234451 25348397 physical association pull down ComPPI,IntAct
TUBG1 TUBA1B 11082048 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
TUBA1B HDAC6 12606581 14525934 23703321 23798680 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
TUBA1B MYC 14525934 25348397 7651436 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
TUBA1B PTP4A1 12235145 14525934 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
TUBA1B PXN 25348397 N/A two hybrid,in vitro,in vivo ComPPI
TUBA1B PFDN5 25348397 N/A in vivo ComPPI
TUBA1B SNAP91 12750376 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
TUBA1B EPN2 12750376 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
TUBA1B MINK1 14525934 15032605 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
TUBA1B ESR1 14525934 15556606 24234451 25348397 25604459 association experimental interaction detection,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
TUBA1B FYN 11826099 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
TUBA1B CUL4A 25348397 N/A physical interaction ComPPI
TUBA1B POLH 25348397 N/A physical interaction ComPPI
TUBA1B ZMYM2 25348397 N/A physical interaction ComPPI
TUBA1B CD247 25348397 N/A physical interaction ComPPI
TUBA1B INO80 20237820 25348397 27898060 N/A physical interaction ComPPI,OmniPath
TUBA1B RICTOR 25348397 N/A physical interaction ComPPI
TUBA1B TOM1L1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TUBA1B KCND3 25348397 N/A physical interaction ComPPI
TUBA1B SNCA 25348397 N/A physical interaction ComPPI
TUBA1B SLC6A3 25348397 N/A physical interaction ComPPI
TUBA1B TUBB1 25348397 N/A physical interaction ComPPI
TUBA1B A2M 25348397 N/A physical interaction ComPPI
TUBA1B PSEN1 25348397 N/A physical interaction ComPPI
TUBA1B TUBA1A 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TUBA1B TUBA1C 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TUBA1B TUBB2A 25348397 N/A physical interaction ComPPI
TUBA1B CCT6A 25348397 N/A physical interaction ComPPI
TUBA1B TUBB4B 25348397 N/A physical interaction ComPPI
TUBA1B TUBB6 25348397 N/A physical interaction ComPPI
TUBA1B MC1R 25348397 N/A physical interaction ComPPI
TUBA1B TUBB3 22939629 24021646 24234451 25348397 26317901 27898060 association,physical association affinity chromatography technology,light scattering,physical interaction,light microscopy ComPPI,IntAct,OmniPath
TUBA1B TUBB2B 25348397 N/A physical interaction ComPPI
TUBA1B LAMP2 25348397 N/A physical interaction ComPPI
TUBA1B RPL5 25348397 N/A physical interaction ComPPI
TUBA1B PSMD1 25348397 N/A physical interaction ComPPI
TUBA1B PSMC4 25348397 N/A physical interaction ComPPI
TUBA1B SSBP1 25348397 N/A physical interaction ComPPI
TUBA1B SNRNP200 25348397 N/A physical interaction ComPPI
TUBA1B U2AF1 25348397 N/A physical interaction ComPPI
TUBA1B RPL18 25348397 N/A physical interaction ComPPI
TUBA1B RCN1 25348397 N/A physical interaction ComPPI
TUBA1B LTA 25348397 N/A physical interaction ComPPI
TUBA1B VDAC1 25348397 N/A physical interaction ComPPI
TUBA1B CCT2 25348397 N/A physical interaction ComPPI
TUBA1B FN1 25348397 N/A physical interaction ComPPI
TUBA1B VCAM1 25348397 N/A physical interaction ComPPI
TUBA1B IQCB1 21565611 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TUBA1B MAP1LC3A 25348397 N/A physical interaction ComPPI
TUBA1B GZMM 25348397 N/A physical interaction ComPPI
TUBA1B PAN2 25348397 N/A physical interaction ComPPI
TUBA1B IGSF8 25348397 N/A physical interaction ComPPI
TUBA1B TERT 25348397 N/A physical interaction ComPPI
TUBA1B SLX1A 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TUBA1B TMEM253 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TUBA1B FBXO6 25348397 N/A physical interaction ComPPI
TUBA1B TARDBP 25348397 N/A physical interaction ComPPI
TUBA1B ASB17 25348397 N/A physical interaction ComPPI
TUBA1B ZBTB1 25348397 N/A physical interaction ComPPI
TUBA1B AP2M1 25348397 N/A physical interaction ComPPI
TUBA1B LGR4 25348397 N/A physical interaction ComPPI
TUBA1B CHORDC1 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TUBA1B MAPT 25348397 N/A physical interaction ComPPI
TUBA1B CEP250 25348397 N/A physical interaction ComPPI
TUBA1B CEP76 25348397 N/A physical interaction ComPPI
TUBA1B TUBGCP2 25348397 N/A physical interaction ComPPI
TUBA1B EML1 25348397 N/A physical interaction ComPPI
TUBA1B FUS 25348397 N/A physical interaction ComPPI
TUBA1B AGTRAP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TUBA1B MTCL1 25348397 N/A physical interaction ComPPI
TUBA1B CUL7 25348397 N/A physical interaction ComPPI
TUBA1B OBSL1 25348397 N/A physical interaction ComPPI
TUBA1B EED 25348397 N/A physical interaction ComPPI
TUBA1B RNF2 25348397 N/A physical interaction ComPPI
TUBA1B FAF2 25348397 N/A physical interaction ComPPI
TUBA1B SUMO2 25348397 N/A physical interaction ComPPI
TUBA1B RPS6KB2 25348397 N/A physical interaction ComPPI
TUBA1B PTEN 25348397 N/A physical interaction ComPPI
TUBA1B SRPK2 25348397 N/A physical interaction ComPPI
TUBA1B OFD1 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TUBA1B XPO1 25348397 N/A physical interaction ComPPI
TUBA1B MYO19 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TUBA1B ARMC6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TUBA1B ASPM 25348397 N/A physical interaction ComPPI
TUBA1B ID2 25348397 N/A physical interaction ComPPI
TUBA1B GAN 25348397 N/A physical interaction ComPPI
TUBA1B SKI 25348397 N/A physical interaction ComPPI
TUBA1B RANBP9 25348397 N/A physical interaction ComPPI
TUBA1B PIWIL1 25348397 N/A physical interaction ComPPI
TUBA1B STMN1 25348397 N/A physical interaction ComPPI
TUBA1B MID1 25348397 N/A physical interaction ComPPI
TUBA1B MID2 25348397 N/A physical interaction ComPPI
TUBA1B ESRRB 25348397 N/A physical interaction ComPPI
TUBA1B ERBB3 25348397 N/A physical interaction ComPPI
TUBA1B CDC37 25348397 N/A physical interaction ComPPI
TUBA1B MTMR2 25348397 N/A physical interaction ComPPI
TUBA1B PPP3CA 25348397 N/A physical interaction ComPPI
TUBA1B TCP11L2 25348397 N/A physical interaction ComPPI
TUBA1B TXNDC9 25348397 N/A physical interaction ComPPI
TUBA1B DLGAP5 25348397 N/A physical interaction ComPPI
TUBA1B CCT6B 25348397 N/A physical interaction ComPPI
TUBA1B CCT7 25348397 N/A physical interaction ComPPI
TUBA1B CCT4 25348397 N/A physical interaction ComPPI
TUBA1B MICU1 25348397 N/A physical interaction ComPPI
TUBA1B HYAL1 25348397 N/A physical interaction ComPPI
TUBA1B CCT3 25348397 N/A physical interaction ComPPI
TUBA1B NDUFAF8 25348397 N/A physical interaction ComPPI
TUBA1B CCND2 25348397 N/A physical interaction ComPPI
TUBA1B HEY1 25348397 N/A physical interaction ComPPI
TUBA1B TES 25348397 N/A physical interaction ComPPI
TUBA1B STARD13 14697242 24234451 25348397 physical association two hybrid ComPPI,IntAct
TUBA1B PRR5 25348397 N/A anti tag coimmunoprecipitation ComPPI
TUBA1B ARHGAP8 25348397 N/A anti tag coimmunoprecipitation ComPPI
TUBA1B PPP2R2B 19156129 24234451 25348397 association pull down ComPPI,IntAct
TUBA1B BAG2 18457437 24234451 25348397 association tandem affinity purification ComPPI,IntAct
TUBA1B RAD52 19338310 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
TUBA1B PEX14 21525035 24234451 25348397 association pull down ComPPI,IntAct
TUBA1B MAGOH 23084401 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
TUBA1B HTR7 19486527 24234451 25348397 association tandem affinity purification ComPPI,IntAct
TUBA1B LRRK2 24234451 24275654 25348397 association pull down ComPPI,IntAct
TUBA1B RIPK4 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
TUBA1B NFKB1 24234451 25348397 25609649 association tandem affinity purification ComPPI,IntAct
TUBA1B PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
TUBA1B KATNA1 24234451 25348397 26929214 association tandem affinity purification ComPPI,IntAct
TUBA1B KATNAL2 24234451 25348397 26929214 association tandem affinity purification ComPPI,IntAct
TUBA1B ANG 24234451 25348397 28777577 association anti bait coimmunoprecipitation ComPPI,IntAct
TUBA1B RRP1B 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
NFKBIA TUBA1B 14525934 25348397 9372968 N/A experimental interaction detection,in vivo ComPPI,HPRD
TCP1 TUBA1B 25348397 N/A physical interaction ComPPI
LGALS2 TUBA1B 25348397 N/A physical interaction ComPPI
PPID TUBA1B 21146485 24234451 25348397 association tandem affinity purification ComPPI,IntAct
FKBPL TUBA1B 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GRM7 TUBA1B 11953448 14525934 N/A experimental interaction detection HPRD
IL7R TUBA1B 20167604 27898060 N/A N/A OmniPath
NUMA1 TUBA1B 11956313 27898060 stimulant N/A OmniPath
TTL TUBA1B 22020298 27898060 inhibition N/A OmniPath

Visualization










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