Gene Information gene info

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GENE：RNF168

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RNF168
FullNmae ring finger protein 168
LocusType gene with protein product
Status Approved
HGNC_id HGNC:26661
EnsembleID ENSG00000163961
Uniprot Q8IYW5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RNF168 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RNF168 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RNF168 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
RNF168 GO:0000151,GO:0003682,GO:0004842,GO:0004842,GO:0004842,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005829,GO:0006302,GO:0006302,GO:0006303,GO:0006511,GO:0006974,GO:0010212,GO:0016567,GO:0031491,GO:0031491,GO:0032991,GO:0034244,GO:0035861,GO:0035861,GO:0036297,GO:0040029,GO:0042393,GO:0042393,GO:0043130,GO:0045190,GO:0045739,GO:0045739,GO:0046872,GO:0070530,GO:0070534,GO:0140852,GO:0140858,GO:0140861,GO:0140861

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RNF168 TP53BP1 19203579 26192618 interaction type N/A ACSN
EGR1 RNF168 19374776 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR RNF168 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 RNF168 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 RNF168 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 RNF168 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 RNF168 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA RNF168 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RNF168 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 RNF168 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RNF168 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001A7F58 RNF168 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CC709 RNF168 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000008F0CF RNF168 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000453664 RNF168 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000E7139 RNF168 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001496AE RNF168 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000048BA36 RNF168 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A RNF168 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 RNF168 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D RNF168 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C RNF168 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 RNF168 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000032BD73 RNF168 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001CE046 RNF168 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000100748 RNF168 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000166778 RNF168 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 RNF168 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
RNF168 TP53BP1 25361965 interaction type N/A PTMCode2
TP53BP1 RNF168 25361965 interaction type N/A PTMCode2
RNF11 RNF168 25361965 interaction type N/A PTMCode2
RNF168 RNF11 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
DDX21 RNF168 25348397 N/A physical interaction ComPPI
DHX15 RNF168 25348397 N/A physical interaction ComPPI
KIF5B RNF168 25348397 N/A physical interaction ComPPI
WBP2 RNF168 25348397 N/A physical interaction ComPPI
TP53BP1 RNF168 22884692 24234451 25348397 29656893 colocalization,association physical interaction,confocal microscopy,proximity-dependent biotin identification ComPPI,IntAct
UBE2D1 RNF168 25348397 N/A physical interaction ComPPI
LAPTM5 RNF168 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
TACC3 RNF168 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TBP RNF168 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GTF2F2 RNF168 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
SUMO1 RNF168 25348397 N/A physical interaction ComPPI
DHX9 RNF168 25348397 N/A physical interaction ComPPI
USP7 RNF168 25348397 25894431 27898060 N/A physical interaction ComPPI,OmniPath
UBE2G2 RNF168 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PSMD11 RNF168 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBB RNF168 16499958 24234451 25348397 N/A pull down,physical interaction ComPPI,IntAct
UBC RNF168 25348397 N/A pull down,physical interaction,physical interaction ComPPI
RPS27A RNF168 25348397 N/A pull down,physical interaction ComPPI
UBA52 RNF168 25348397 N/A pull down,physical interaction ComPPI
UBE2N RNF168 19203578 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PABPC4 RNF168 25348397 N/A physical interaction ComPPI
DCTN1 RNF168 25348397 N/A physical interaction ComPPI
UBR5 RNF168 22884692 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
MKI67 RNF168 25348397 N/A physical interaction ComPPI
EWSR1 RNF168 25348397 N/A physical interaction ComPPI
RABGEF1 RNF168 25348397 N/A in vitro ComPPI
BRCA2 RNF168 25348397 N/A physical interaction ComPPI
H2BC21 RNF168 25348397 N/A physical interaction ComPPI
H2AC18 RNF168 25348397 N/A physical interaction ComPPI
JMJD1C RNF168 25348397 N/A pull down,physical interaction,physical interaction ComPPI
RNF168 RNF11 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
RNF168 H2AC20 25348397 N/A physical interaction ComPPI
RNF168 H2AX 19203578 24234451 25348397 colocalization physical interaction,confocal microscopy ComPPI,IntAct
RNF168 HERC2 25348397 N/A physical interaction ComPPI
RNF168 HERC2P3 25348397 N/A physical interaction ComPPI
RNF168 KDM4A 25348397 N/A physical interaction ComPPI
RNF168 UBE2D3 19500350 22373579 25348397 27898060 N/A physical interaction ComPPI,OmniPath
RNF168 UBE2E1 25348397 N/A physical interaction ComPPI
RNF168 DDX1 25348397 N/A physical interaction ComPPI
RNF168 POC1A 25348397 N/A physical interaction ComPPI
RNF168 TAF15 25348397 N/A physical interaction ComPPI
RNF168 SMARCA5 25348397 N/A physical interaction ComPPI
RNF168 TRIP12 22884692 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
RNF168 KDM1A 25348397 N/A physical interaction ComPPI
RNF168 SRCAP 25348397 N/A physical interaction ComPPI
RNF168 CCDC174 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF168 NUB1 25348397 N/A physical interaction ComPPI
RNF168 RPRD1B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF168 DENND10 25348397 N/A physical interaction ComPPI
RNF168 SUMO2 25348397 26675234 27898060 N/A physical interaction ComPPI,OmniPath
RNF168 SUMO3 25348397 N/A physical interaction ComPPI
RNF168 H1-2 24234451 25348397 26503038 physical association pull down,physical interaction ComPPI,IntAct
RNF168 H2AZ1 25348397 N/A physical interaction ComPPI
RNF168 H2AC4 25348397 N/A physical interaction ComPPI
RNF168 FOXM1 25348397 N/A physical interaction ComPPI
RNF168 PALB2 25348397 N/A physical interaction ComPPI
RNF168 TOP2A 25348397 N/A physical interaction ComPPI
RNF168 TJP1 25348397 N/A physical interaction ComPPI
RNF168 PCM1 25348397 N/A physical interaction ComPPI
RNF168 PDCD11 25348397 N/A physical interaction ComPPI
RNF168 NCL 25348397 N/A physical interaction ComPPI
RNF168 HNRNPM 25348397 N/A physical interaction ComPPI
RNF168 RAI14 25348397 N/A physical interaction ComPPI
RNF168 LIMA1 25348397 N/A physical interaction ComPPI
RNF168 DBN1 25348397 N/A physical interaction ComPPI
RNF168 USP10 25348397 N/A physical interaction ComPPI
RNF168 H1-0 24234451 25348397 26503038 N/A pull down,physical interaction ComPPI,IntAct
RNF168 H2AW 24234451 25348397 26503038 N/A pull down,physical interaction ComPPI,IntAct
RNF168 H1-10 24234451 25348397 26503038 physical association pull down,physical interaction ComPPI,IntAct
RNF168 RNF169 21252943 24234451 25348397 association pull down ComPPI,IntAct
RNF168 ALAS1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RNF168 TRIM8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RNF168 BRCA1 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
BCL10 RNF168 25348397 N/A physical interaction ComPPI
ECPAS RNF168 25348397 N/A physical interaction ComPPI
PDIA4 RNF168 24234451 30021884 physical association cross-linking study IntAct
OTUB1 RNF168 21130715 27898060 inhibition N/A OmniPath
RNF8 RNF168 20385750 27898060 stimulant N/A OmniPath
RNF168 H2AX 18443409 19203578 19342239 27898060 stimulant N/A OmniPath
HERC2 RNF168 20023648 27898060 stimulant N/A OmniPath
H2AC11 RNF168 19203578 27898060 stimulant N/A OmniPath

Visualization










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