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GENE：CHKA

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CHKA
FullNmae choline kinase alpha
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1937
EnsembleID ENSG00000110721
Uniprot P35790

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CHKA autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CHKA GO:0004103,GO:0004103,GO:0004104,GO:0004305,GO:0004305,GO:0004713,GO:0005524,GO:0005737,GO:0005811,GO:0005829,GO:0005829,GO:0006629,GO:0006646,GO:0006646,GO:0006646,GO:0006656,GO:0006657,GO:0006869,GO:0016310,GO:0042803

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CHKA hsa:1119 path:hsa00564 Glycerophospholipid metabolism - Homo sapiens (human)
CHKA hsa:1119 path:hsa01100 Metabolic pathways - Homo sapiens (human)
CHKA hsa:1119 path:hsa05231 Choline metabolism in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
HIF1A CHKA 18172309 23180781 physical association anti tag coimmunoprecipitation InnateDB
APP CHKA 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
GATA2 CHKA 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 CHKA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CHKA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CHKA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 CHKA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 CHKA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CHKA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CHKA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CHKA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CHKA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF CHKA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 CHKA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 CHKA 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
SRC CHKA 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
RCC1 CHKA 12062430 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PSEN2 CHKA 25348397 N/A physical interaction ComPPI
SKP2 CHKA 25348397 N/A physical interaction ComPPI
FCHSD2 CHKA 18654987 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CHKA DEPTOR 25348397 N/A physical interaction ComPPI
CHKA APP 25348397 N/A physical interaction ComPPI
SRC CHKA 21822308 27898060 N/A N/A OmniPath

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