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GENE：PGRMC2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PGRMC2
FullNmae progesterone receptor membrane component 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16089
EnsembleID ENSG00000164040
Uniprot O15173

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PGRMC2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PGRMC2 GO:0003707,GO:0005496,GO:0005515,GO:0005635,GO:0005783,GO:0005783,GO:0012505,GO:0015232,GO:0015886,GO:0016020,GO:0016020,GO:0020037,GO:0043401,GO:0060612

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PGRMC2 hsa:10424 path:hsa04080 Neuroactive ligand-receptor interaction - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR PGRMC2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 PGRMC2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 PGRMC2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 PGRMC2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 PGRMC2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 PGRMC2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PGRMC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PGRMC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PGRMC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PGRMC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PGRMC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PGRMC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PGRMC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PGRMC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PGRMC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PGRMC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 PGRMC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 PGRMC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 PGRMC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 PGRMC2 18668040 22473208 25416803 mrna cleavage,inhibition experimental interaction detection,clip TarBase
URS000009262D PGRMC2 18591254 25416803 mrna cleavage,inhibition array technology TarBase
URS000011A030 PGRMC2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000435A77 PGRMC2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000458AD2 PGRMC2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000383DF4 PGRMC2 22100165 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GET3 PGRMC2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LMNA PGRMC2 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PMP22 PGRMC2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
VAPA PGRMC2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NTRK1 PGRMC2 25348397 N/A physical interaction ComPPI
CANX PGRMC2 24234451 25348397 29568061 association pull down,proximity-dependent biotin identification ComPPI,IntAct
CDH1 PGRMC2 25348397 N/A physical interaction ComPPI
CFTR PGRMC2 25348397 N/A physical interaction ComPPI
EVC2 PGRMC2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
BAG4 PGRMC2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DUSP22 PGRMC2 25348397 N/A physical interaction ComPPI
PMF1 PGRMC2 25348397 N/A physical interaction ComPPI
ITGAM PGRMC2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DERL1 PGRMC2 25348397 N/A physical interaction ComPPI
C5 PGRMC2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TGOLN2 PGRMC2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
IKBKE PGRMC2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
MICA PGRMC2 25348397 N/A physical interaction ComPPI
PGRMC1 PGRMC2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NUP160 PGRMC2 25348397 N/A physical interaction ComPPI
LPAR3 PGRMC2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SFXN1 PGRMC2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TF PGRMC2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GHITM PGRMC2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ABCC1 PGRMC2 25348397 N/A physical interaction ComPPI
CTDNEP1 PGRMC2 25348397 N/A physical interaction ComPPI
TECR PGRMC2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PGRMC2 COX20 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PGRMC2 SERPINA5 24234451 30021884 physical association cross-linking study IntAct

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