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GENE：LSS

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol LSS
FullNmae lanosterol synthase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6708
EnsembleID ENSG00000160285
Uniprot P48449

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
LSS autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
LSS GO:0000250,GO:0000250,GO:0000250,GO:0000250,GO:0005515,GO:0005789,GO:0005789,GO:0005811,GO:0005811,GO:0006694,GO:0006695,GO:0006695,GO:0006695,GO:0016020,GO:0016104,GO:0031647

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
LSS hsa:4047 path:hsa00100 Steroid biosynthesis - Homo sapiens (human)
LSS hsa:4047 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR LSS 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
YY1 LSS 17925399 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 LSS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF LSS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 LSS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 LSS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS LSS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF LSS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 LSS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HDAC3 LSS 17925399 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 LSS 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000065D58 LSS 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00004AC389 LSS 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000016D2D4 LSS 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
CYP51A1 LSS 25361965 interaction type N/A PTMCode2
LSS CYP51A1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
FIP1L1 LSS 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CIB1 LSS 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NTRK1 LSS 25348397 N/A physical interaction ComPPI
HNRNPL LSS 25348397 N/A physical interaction ComPPI
XPO1 LSS 25348397 N/A physical interaction ComPPI
NR4A1 LSS 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ALOX5 LSS 25348397 N/A physical interaction ComPPI
TNFRSF10A LSS 25348397 N/A physical interaction ComPPI
MYH9 LSS 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PNKD LSS 25348397 N/A physical interaction ComPPI
YIF1A LSS 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GATD1 LSS 25348397 N/A physical interaction ComPPI
MYO5C LSS 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TMEM167B LSS 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP4A LSS 25348397 N/A physical interaction ComPPI
LSS LYPD4 25348397 N/A physical interaction ComPPI
LSS GML 25348397 N/A physical interaction ComPPI
LSS SLC10A1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LSS SLC10A6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LSS AQP6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TMEM86B LSS 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GPR35 LSS 24234451 28298427 physical association ubiquitin reconstruction IntAct

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