Gene Information gene info

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GENE：CCNA1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CCNA1
FullNmae cyclin A1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1577
EnsembleID ENSG00000133101
Uniprot P78396

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CCNA1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CCNA1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CCNA1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CCNA1 GO:0000079,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0007141,GO:0007283,GO:0015630,GO:0016538,GO:0044772,GO:0051301,GO:0097123,GO:0097124

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CCNA1 hsa:8900 path:hsa04110 Cell cycle - Homo sapiens (human)
CCNA1 hsa:8900 path:hsa04152 AMPK signaling pathway - Homo sapiens (human)
CCNA1 hsa:8900 path:hsa04218 Cellular senescence - Homo sapiens (human)
CCNA1 hsa:8900 path:hsa04914 Progesterone-mediated oocyte maturation - Homo sapiens (human)
CCNA1 hsa:8900 path:hsa05161 Hepatitis B - Homo sapiens (human)
CCNA1 hsa:8900 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
CCNA1 hsa:8900 path:hsa05166 Human T-cell leukemia virus 1 infection - Homo sapiens (human)
CCNA1 hsa:8900 path:hsa05169 Epstein-Barr virus infection - Homo sapiens (human)
CCNA1 hsa:8900 path:hsa05200 Pathways in cancer - Homo sapiens (human)
CCNA1 hsa:8900 path:hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human)
CCNA1 hsa:8900 path:hsa05203 Viral carcinogenesis - Homo sapiens (human)
CCNA1 hsa:8900 path:hsa05221 Acute myeloid leukemia - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EP300 CCNA1 15286281 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
MYB CCNA1 10590070 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
SP1 CCNA1 10196209 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
SP3 CCNA1 10196209 trascriptional regulation,stimulation electrophoretic mobility shift assay TFlink
SMARCA4 CCNA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CCNA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CCNA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 CCNA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 CCNA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ATF1 CCNA1 12044952 trascriptional regulation,stimulation inferred by curator TFlink
CREM CCNA1 7760825 trascriptional regulation,stimulation inferred by curator TFlink
KDM4B CCNA1 20682797 trascriptional regulation,stimulation inferred by curator TFlink
MYBL2 CCNA1 11264176 15922873 trascriptional regulation,stimulation inferred by curator TFlink
RARA CCNA1 11090075 trascriptional regulation,stimulation inferred by curator TFlink
TP53 CCNA1 17530187 trascriptional regulation,stimulation inferred by curator TFlink
ATF2 CCNA1 N/A trascriptional regulation,stimulation inferred by curator TFlink
CREB1 CCNA1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000324096 CCNA1 18379589 rna interference,inhibition experimental interaction detection miRSponge
URS0000237AF9 CCNA1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000324096 CCNA1 18379589 25416803 mrna cleavage,inhibition experimental interaction detection TarBase

Source Target Pmid Interactiontype Methods Database
CDC6 CCNA1 25361965 interaction type N/A PTMCode2
CCNA1 CDC6 25361965 interaction type N/A PTMCode2
CDKN1A CCNA1 25361965 interaction type N/A PTMCode2
CCNA1 CDKN1A 25361965 interaction type N/A PTMCode2
MYBL2 CCNA1 25361965 interaction type N/A PTMCode2
CCNA1 MYBL2 25361965 interaction type N/A PTMCode2
CDKN1B CCNA1 25361965 interaction type N/A PTMCode2
CCNA1 CDKN1B 25361965 interaction type N/A PTMCode2
CCNA1 MCM4 25361965 interaction type N/A PTMCode2
MCM4 CCNA1 25361965 interaction type N/A PTMCode2
CCNA1 MCM6 25361965 interaction type N/A PTMCode2
MCM6 CCNA1 25361965 interaction type N/A PTMCode2
CCNA1 MCM2 25361965 interaction type N/A PTMCode2
MCM2 CCNA1 25361965 interaction type N/A PTMCode2
CCNA1 CDK2 25361965 interaction type N/A PTMCode2
CDK2 CCNA1 25361965 interaction type N/A PTMCode2
CCNA1 SKP2 25361965 interaction type N/A PTMCode2
SKP2 CCNA1 25361965 interaction type N/A PTMCode2
CCNA1 PROCA1 25361965 interaction type N/A PTMCode2
PROCA1 CCNA1 25361965 interaction type N/A PTMCode2
CCNA1 CDC20 25361965 interaction type N/A PTMCode2
CDC20 CCNA1 25361965 interaction type N/A PTMCode2
CCNA1 CKS1B 25361965 interaction type N/A PTMCode2
CKS1B CCNA1 25361965 interaction type N/A PTMCode2
CCNA1 CTNNB1 25361965 interaction type N/A PTMCode2
CTNNB1 CCNA1 25361965 interaction type N/A PTMCode2
CCNA1 BRCA1 25361965 interaction type N/A PTMCode2
BRCA1 CCNA1 25361965 interaction type N/A PTMCode2
CCNA1 KLHDC9 25361965 interaction type N/A PTMCode2
KLHDC9 CCNA1 25361965 interaction type N/A PTMCode2
CCNA1 SUMO1 25361965 interaction type N/A PTMCode2
SUMO1 CCNA1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
ORC1 CCNA1 11931757 24234451 25348397 association coimmunoprecipitation ComPPI,IntAct
CKS1B CCNA1 25348397 N/A physical interaction ComPPI
CDKN1A CCNA1 10022926 14525934 15232106 24234451 25241761 25348397 29997244 7478582 8756624 association,physical association bioluminescence resonance energy transfer,experimental interaction detection,protein array,pull down,physical interaction,in vitro,luminescence based mammalian interactome mapping,proximity ligation assay ComPPI,HPRD,IntAct
CDKN1B CCNA1 10022926 14525934 18692475 24234451 25348397 29997244 7478582 physical association bioluminescence resonance energy transfer,experimental interaction detection,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,in vivo,luminescence based mammalian interactome mapping ComPPI,HPRD,IntAct
MCM6 CCNA1 14525934 15232106 24234451 25348397 N/A experimental interaction detection,protein array,physical interaction,in vitro ComPPI,HPRD,IntAct
MCM2 CCNA1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TUFM CCNA1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RACK1 CCNA1 14525934 15159402 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
LARP4B CCNA1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CSNK1D CCNA1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SP1 CCNA1 25348397 N/A physical interaction ComPPI
SRC CCNA1 25348397 N/A physical interaction ComPPI
RB1 CCNA1 10022926 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
COPS5 CCNA1 25348397 N/A physical interaction ComPPI
FZR1 CCNA1 25348397 N/A physical interaction ComPPI
RBM4 CCNA1 14525934 15159402 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
MYBL2 CCNA1 11264176 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CSNK1E CCNA1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RBL2 CCNA1 10022926 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
E2F1 CCNA1 10022926 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
RPA1 CCNA1 25348397 N/A physical interaction ComPPI
PPP1CA CCNA1 25348397 N/A physical interaction ComPPI
XPO5 CCNA1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
XRCC6 CCNA1 14525934 15159402 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
PPP2CB CCNA1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CAPZA1 CCNA1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
EIF3F CCNA1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ORC2 CCNA1 11931757 24234451 25348397 association coimmunoprecipitation ComPPI,IntAct
CCNA1 MCM4 14525934 15232106 24234451 25348397 N/A experimental interaction detection,protein array,physical interaction,in vitro ComPPI,HPRD,IntAct
CCNA1 GPS2 14525934 15159402 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
CCNA1 KLHDC9 14525934 15159402 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
CCNA1 CABLES1 11733001 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CCNA1 ARID2 14525934 15159402 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
CCNA1 INCA1 25348397 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI
CCNA1 RBL1 10022926 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CCNA1 CDC25A 10926775 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CCNA1 CDK2 10559988 14525934 16777603 24234451 25241761 25348397 9041194 physical association two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,proximity ligation assay,two hybrid ComPPI,HPRD,IntAct
CCNA1 BRCA1 10373534 14525934 25348397 9244350 N/A experimental interaction detection,in vitro ComPPI,HPRD
CCNA1 PROCA1 14525934 15159402 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
CCNA1 CCAR2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CCNA1 TGFB1I1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CCNA1 VPS18 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CCNA1 MCC 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CCNA1 PRKN 25348397 N/A physical interaction ComPPI
CCNA1 H1-1 14985333 25348397 27898060 8397206 8565853 9344597 9860976 N/A physical interaction ComPPI,OmniPath
CCNA1 H2BC1 25348397 N/A physical interaction ComPPI
CCNA1 CDK1 14525934 25348397 8565853 N/A experimental interaction detection,physical interaction ComPPI,HPRD
CCNA1 CUX1 25348397 N/A physical interaction ComPPI
CCNA1 CUX1 25348397 N/A physical interaction ComPPI
CCNA1 CDC20 25348397 N/A physical interaction ComPPI
CCNA1 SKP2 10652300 16774918 17308064 19270695 25348397 27898060 N/A physical interaction ComPPI,OmniPath
CCNA1 CDT1 14993212 24234451 25348397 association coimmunoprecipitation,physical interaction ComPPI,IntAct
CCNA1 USP2 25348397 N/A physical interaction ComPPI
CCNA1 H1-5 25348397 N/A physical interaction ComPPI
CCNA1 PGR 25348397 N/A physical interaction ComPPI
CCNA1 NPAT 25348397 N/A physical interaction ComPPI
CCNA1 CUL1 25348397 N/A physical interaction ComPPI
CCNA1 COPS6 25348397 N/A physical interaction ComPPI
CCNA1 CTNNB1 25348397 N/A physical interaction ComPPI
CCNA1 HECW2 25348397 N/A physical interaction ComPPI
CCNA1 CKS2 25348397 N/A physical interaction ComPPI
CCNA1 CCNA2 25348397 N/A physical interaction ComPPI
CCNA1 PTK2 17353931 24234451 25241761 25348397 physical association anti bait coimmunoprecipitation,physical interaction,proximity ligation assay ComPPI,IntAct
CCNA1 ACLY 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CCNA1 VHL 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CCNA1 OAT 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CCNA1 GANAB 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CCNA1 LRRC59 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CCNA1 MCM3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CCNA1 MTHFD1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CCNA1 SEC13 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CCNA1 APEX1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CCNA1 ATXN2L 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CCNA1 PAICS 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CCNA1 PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CCNA1 TRIM28 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CCNA1 PFAS 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CCNA1 ACAT2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CCNA1 LRPPRC 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CCNA1 EIF3I 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CCNA1 STOML2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CCNA1 GOT2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CCNA1 CCNA1 11264176 14525934 N/A experimental interaction detection HPRD
ELAVL1 CCNA1 12963828 18519672 27898060 stimulant N/A OmniPath

Visualization










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