Gene Information gene info

GENE:CNOT3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CNOT3
FullNmae CCR4-NOT transcription complex subunit 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7879
EnsembleID ENSG00000088038
Uniprot O75175

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CNOT3 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CNOT3 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CNOT3 GO:0000289,GO:0000289,GO:0000932,GO:0000932,GO:0001829,GO:0005515,GO:0005634,GO:0005829,GO:0006355,GO:0030014,GO:0030014,GO:0030015,GO:0031047,GO:0120162,GO:2000036,GO:2000036

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CNOT3 hsa:4849 path:hsa03018 RNA degradation - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 CNOT3 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 CNOT3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TFAP2C CNOT3 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 CNOT3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 CNOT3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CNOT3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CNOT3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR CNOT3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002367FA CNOT3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000013DD8 CNOT3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000031E12 CNOT3 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
CNOT3 CNOT2 25361965 interaction type N/A PTMCode2
CNOT2 CNOT3 25361965 interaction type N/A PTMCode2
CNOT3 CNOT8 25361965 interaction type N/A PTMCode2
CNOT8 CNOT3 25361965 interaction type N/A PTMCode2
CNOT3 CAND1 25361965 interaction type N/A PTMCode2
CAND1 CNOT3 25361965 interaction type N/A PTMCode2
CNOT3 CNOT7 25361965 interaction type N/A PTMCode2
CNOT7 CNOT3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CDC5L CNOT3 20467437 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
NANOS2 CNOT3 25348397 N/A physical interaction ComPPI
NLK CNOT3 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
MMP7 CNOT3 25348397 N/A physical interaction ComPPI
TOB1 CNOT3 18377426 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
CREBBP CNOT3 14525934 15752756 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
GADD45B CNOT3 25348397 N/A physical interaction ComPPI
NTRK1 CNOT3 25348397 N/A physical interaction ComPPI
XPO1 CNOT3 25348397 N/A physical interaction ComPPI
ID3 CNOT3 18255255 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SOX2 CNOT3 25348397 N/A physical interaction ComPPI
NCS1 CNOT3 25348397 N/A physical interaction ComPPI
CAND1 CNOT3 12207886 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
CNOT7 CNOT3 25348397 N/A physical interaction ComPPI
CNOT8 CNOT3 10637334 14525934 16778766 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct
NANOS1 CNOT3 25348397 N/A physical interaction ComPPI
HNRNPLL CNOT3 25348397 N/A physical interaction ComPPI
CIRBP CNOT3 25348397 N/A physical interaction ComPPI
CNOT1 CNOT3 14525934 16778766 24234451 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
CNOT2 CNOT3 14525934 16189514 16778766 21984185 24234451 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,in vivo,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
CNOT3 CAND2 12207886 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
CNOT3 CNOT9 25348397 N/A physical interaction ComPPI
CNOT3 CNOT6L 17452450 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT3 CNOT6 17452450 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT3 TNRC6A 25348397 N/A physical interaction ComPPI
CNOT3 TNRC6C 21981923 21984185 24234451 25348397 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
CNOT3 NANOS3 25348397 N/A physical interaction ComPPI
CNOT3 CAPZA2 25348397 N/A physical interaction ComPPI
CNOT3 TNRC6B 25348397 N/A physical interaction ComPPI
CNOT3 CEP152 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CNOT3 CNTROB 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CNOT3 NINL 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CNOT3 STIL 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CNOT3 MEX3C 25348397 N/A physical interaction ComPPI
CNOT3 RC3H1 25348397 N/A physical interaction ComPPI
CNOT3 CNOT11 25348397 N/A physical interaction ComPPI
CNOT3 RIBC1 25348397 N/A physical interaction ComPPI
SRRM1 CNOT3 25348397 N/A physical interaction ComPPI
TEX13A CNOT3 25348397 N/A physical interaction ComPPI
SMARCB1 CNOT3 24234451 30108113 association proximity-dependent biotin identification IntAct
STK38L CNOT3 24234451 30108113 association proximity-dependent biotin identification IntAct
TANK CNOT3 24234451 30561431 association virotrap IntAct
OAT CNOT3 24234451 30021884 physical association cross-linking study IntAct

Visualization