GENE:CCNL1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | CCNL1 |
| FullNmae | cyclin L1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:20569 |
| EnsembleID | ENSG00000163660 |
| Uniprot | Q9UK58 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| CCNL1 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| CCNL1 | GO:0000307,GO:0000307,GO:0005515,GO:0005634,GO:0005634,GO:0006357,GO:0016538,GO:0016607,GO:0042981,GO:0043484,GO:0043484,GO:0046605,GO:0051726 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CDK11A | CCNL1 | 22988298 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| ISG15 | CCNL1 | 16009940 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| APP | CCNL1 | 21832049 23180781 | physical association | protein array | InnateDB |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| E2F4 | CCNL1 | 17531812 18971253 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| ETS1 | CCNL1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | CCNL1 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | CCNL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | CCNL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | CCNL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | CCNL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | CCNL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | CCNL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | CCNL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | CCNL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000035CC3E | CCNL1 | 16331254 25416803 | mrna cleavage,inhibition | array technology,northern blot | TarBase |
| URS00000EED18 | CCNL1 | 21566225 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
| URS0000029EBD | CCNL1 | 24608802 25416803 26043836 | mrna cleavage,inhibition | experimental interaction detection,western blot,chromatin immunoprecipitation assay,quantitative reverse transcription pcr | TarBase |
| URS000027080C | CCNL1 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000195F5B | CCNL1 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000610EFA | CCNL1 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002ECEE4 | CCNL1 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000043D2C1 | CCNL1 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004BC299 | CCNL1 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000045DBD | CCNL1 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006FDD4 | CCNL1 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| MCM2 | CCNL1 | 25361965 | interaction type | N/A | PTMCode2 |
| CCNL1 | MCM2 | 25361965 | interaction type | N/A | PTMCode2 |
| CDC6 | CCNL1 | 25361965 | interaction type | N/A | PTMCode2 |
| CCNL1 | CDC6 | 25361965 | interaction type | N/A | PTMCode2 |
| CCNB2 | CCNL1 | 25361965 | interaction type | N/A | PTMCode2 |
| CCNL1 | CCNB2 | 25361965 | interaction type | N/A | PTMCode2 |
| CDK4 | CCNL1 | 25361965 | interaction type | N/A | PTMCode2 |
| CCNL1 | CDK4 | 25361965 | interaction type | N/A | PTMCode2 |
| CDK6 | CCNL1 | 25361965 | interaction type | N/A | PTMCode2 |
| CCNL1 | CDK6 | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SAP30BP | CCNL1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| SORBS3 | CCNL1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| ISG15 | CCNL1 | 25348397 | N/A | physical interaction | ComPPI |
| KRTAP12-2 | CCNL1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| APPBP2 | CCNL1 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| SREK1IP1 | CCNL1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| PRPF40A | CCNL1 | 25348397 | N/A | two hybrid | ComPPI |
| SRSF2 | CCNL1 | 11683997 14525934 25348397 | N/A | two hybrid,experimental interaction detection,in vitro,two hybrid | ComPPI,HPRD |
| CSNK2A2 | CCNL1 | 23455922 24234451 25348397 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| CDK7 | CCNL1 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| ZRSR2 | CCNL1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| TFIP11 | CCNL1 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| RAD51D | CCNL1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| CCNL1 | CDK11A | 11683997 11980906 14623875 22988298 25348397 27898060 | N/A | physical interaction,in vitro | ComPPI,OmniPath |
| CCNL1 | CDK11B | 25348397 | N/A | physical interaction | ComPPI |
| CCNL1 | APP | 25348397 | N/A | physical interaction | ComPPI |
| CCNL1 | JMJD6 | 23455924 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| CCNL1 | RNPS1 | 24234451 25348397 26496610 | association,physical association | anti tag coimmunoprecipitation,physical interaction,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| CCNL1 | MMTAG2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| CCNL1 | NKAPD1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| CCNL1 | DVL3 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| CCNL1 | ZRANB1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| CCNL1 | PRDM6 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| CCNL1 | RSRP1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| CCNL1 | RRP1B | 20926688 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| FAM133A | CCNL1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| ISG15 | CCNL1 | 16009940 27898060 | N/A | N/A | OmniPath |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00009C2E90 | CCNL1 | 27087310 | direct interaction,inhibition | N/A | NPInter |
