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GENE：PER3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PER3
FullNmae period circadian regulator 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8847
EnsembleID ENSG00000049246
Uniprot P56645

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PER3 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PER3 GO:0000122,GO:0000122,GO:0000976,GO:0001222,GO:0005515,GO:0005634,GO:0005634,GO:0005737,GO:0005737,GO:0019900,GO:0031625,GO:0032922,GO:0043153,GO:0045187,GO:0050821

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PER3 hsa:8863 path:hsa04710 Circadian rhythm - Homo sapiens (human)
PER3 hsa:8863 path:hsa04713 Circadian entrainment - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
YBX1 PER3 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 PER3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PER3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PER3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PER3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PER3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PER3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ARNTL PER3 22750052 trascriptional regulation,stimulation inferred by curator TFlink
CLOCK PER3 22750052 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 PER3 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000009262D PER3 18591254 25416803 mrna cleavage,inhibition array technology TarBase
URS000007F792 PER3 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS000008931A PER3 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS000014F13C PER3 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005FDE70 PER3 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003AD2AA PER3 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002394F5 PER3 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000334286 PER3 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002CBC6D PER3 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001CE046 PER3 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003B6B84 PER3 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
NPAS2 PER3 25361965 interaction type N/A PTMCode2
PER3 NPAS2 25361965 interaction type N/A PTMCode2
CSNK1E PER3 25361965 interaction type N/A PTMCode2
PER3 CSNK1E 25361965 interaction type N/A PTMCode2
PER2 PER3 25361965 interaction type N/A PTMCode2
PER3 PER2 25361965 interaction type N/A PTMCode2
CSNK1D PER3 25361965 interaction type N/A PTMCode2
PER3 CSNK1D 25361965 interaction type N/A PTMCode2
PER3 CHEK2 25361965 interaction type N/A PTMCode2
CHEK2 PER3 25361965 interaction type N/A PTMCode2
PER3 ARNTL 25361965 interaction type N/A PTMCode2
ARNTL PER3 25361965 interaction type N/A PTMCode2
PER1 PER3 25361965 interaction type N/A PTMCode2
PER3 PER1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CSNK1D PER3 11865049 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SP1 PER3 14525934 25348397 27898060 7622044 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
CSNK1E PER3 10899319 11865049 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
ATM PER3 21070773 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PER3 CLOCK 14525934 14701732 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PER3 PER1 10837028 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PER3 ARNTL 14525934 14701732 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PER3 PER2 10837028 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PER3 CRY2 14525934 14701732 15689618 24234451 25348397 26496610 27898060 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct,OmniPath
PER3 CRY1 10428031 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PER3 CHEK2 21070773 24234451 25348397 27898060 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
PER3 AVL9 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PER3 CCDC88A 25348397 N/A physical interaction ComPPI
PER3 MIB1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PER3 FANCA 25348397 N/A physical interaction ComPPI
DHRS2 PER3 24234451 30021884 physical association cross-linking study IntAct
PER3 ARNTL 14701732 18662546 27898060 inhibition N/A OmniPath

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