Gene Information gene info

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GENE：RAD17

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RAD17
FullNmae RAD17 checkpoint clamp loader component
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9807
EnsembleID ENSG00000152942
Uniprot O75943

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RAD17 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RAD17 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
RAD17 GO:0000076,GO:0000077,GO:0000781,GO:0003682,GO:0003689,GO:0005515,GO:0005524,GO:0005634,GO:0005654,GO:0005654,GO:0005730,GO:0006281,GO:0006974,GO:0008156,GO:0031389,GO:0031573,GO:0033314,GO:0042325

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ATRIP RAD17 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
ATR RAD17 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
CLSPN RAD17 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
RAD17 TOPBP1 11877377 12766152 15459660 15485915 15798197 16530042 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17582221 18677104 19282663 19622404 19793801 26192618 interaction type N/A ACSN
RAD17 HUS1 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
RAD17 RAD1 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
RAD17 PPP5C 14871926 15459660 16260606 16885023 17303408 26192618 association N/A ACSN
RAD17 CHEK1 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
RPA1 RAD17 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
RPA2 RAD17 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
RPA3 RAD17 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
RAD17 ORC1 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
RAD17 ORC2 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
RAD17 ORC3 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
RAD17 ORC4 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
RAD17 ORC5 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
RAD17 ORC6 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
RAD17 MCM2 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
RAD17 MCM3 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
RAD17 MCM4 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
RAD17 MCM5 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
RAD17 MCM6 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
RAD17 MCM7 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
RAD17 CDT1 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
RAD17 CDC6 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
RAD17 CDC45 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
RAD17 CDC7 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
RAD17 DBF4 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
RAD17 TIPIN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
RAD17 ATM 10608806 23180781 phosphorylation reaction in-gel kinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
GATA2 RAD17 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 RAD17 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RAD17 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 RAD17 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RAD17 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF RAD17 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001CC379 RAD17 23249749 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
ATR RAD17 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
ATM RAD17 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
RAD17 ATM 25361965 interaction type N/A PTMCode2
RAD9A RAD17 25361965 interaction type N/A PTMCode2
RAD17 RAD9A 25361965 interaction type N/A PTMCode2
MCM7 RAD17 25361965 interaction type N/A PTMCode2
RAD17 MCM7 25361965 interaction type N/A PTMCode2
RAD17 ATR 25361965 interaction type N/A PTMCode2
PCNA RAD17 25361965 interaction type N/A PTMCode2
RAD17 PCNA 25361965 interaction type N/A PTMCode2
RFC4 RAD17 25361965 interaction type N/A PTMCode2
RAD17 RFC4 25361965 interaction type N/A PTMCode2
RAD17 RAD9B 25361965 interaction type N/A PTMCode2
RAD9B RAD17 25361965 interaction type N/A PTMCode2
RAD17 RFC5 25361965 interaction type N/A PTMCode2
RFC5 RAD17 25361965 interaction type N/A PTMCode2
RFC2 RAD17 25361965 interaction type N/A PTMCode2
RAD17 RFC2 25361965 interaction type N/A PTMCode2
HUS1 RAD17 25361965 interaction type N/A PTMCode2
RAD17 HUS1 25361965 interaction type N/A PTMCode2
CLSPN RAD17 25361965 interaction type N/A PTMCode2
RAD17 CLSPN 25361965 interaction type N/A PTMCode2
RAD1 RAD17 25361965 interaction type N/A PTMCode2
RAD17 RAD1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
USP20 RAD17 19615732 24234451 24923443 25348397 27898060 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
PCNA RAD17 25348397 N/A physical interaction,fluorescence microscopy ComPPI
POLE4 RAD17 25348397 N/A physical interaction ComPPI
POLE3 RAD17 25348397 N/A physical interaction ComPPI
ATR RAD17 10608806 11418864 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PRKDC RAD17 25348397 N/A physical interaction ComPPI
FZR1 RAD17 20424596 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CDH1 RAD17 25348397 N/A physical interaction ComPPI
RFC2 RAD17 14624239 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
HUS1 RAD17 10884395 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
RAD9A RAD17 10884395 12578958 14525934 20424596 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
POLE RAD17 14500819 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
ATM RAD17 10608806 11418864 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
COPS7A RAD17 25348397 N/A physical interaction ComPPI
RFC5 RAD17 14624239 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX RAD17 25348397 N/A physical interaction ComPPI
MRE11 RAD17 24234451 24534091 25348397 association,physical association anti bait coimmunoprecipitation ComPPI,IntAct
NBN RAD17 24234451 24534091 25348397 association,physical association anti bait coimmunoprecipitation,pull down ComPPI,IntAct
RAD50 RAD17 24234451 24534091 25348397 association,physical association anti bait coimmunoprecipitation ComPPI,IntAct
FOXO3 RAD17 25348397 N/A physical interaction ComPPI
RFC4 RAD17 11907025 14525934 14624239 24234451 25348397 association anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
RFC3 RAD17 14624239 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RAD17 SNU13 10593953 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,OmniPath
RAD17 RAD1 25348397 N/A physical interaction,in vitro,in vivo ComPPI
RAD17 MCM7 14525934 15538388 25348397 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD
RAD17 POLE2 25348397 N/A physical interaction ComPPI
RAD17 RFC1 25348397 N/A physical interaction ComPPI
RAD17 ALK 25348397 N/A physical interaction ComPPI
RAD17 CLSPN 25348397 N/A physical interaction ComPPI
RAD17 CBX6 21282530 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
RAD17 CBX7 21282530 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
RAD17 PRMT6 23455924 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RAD9B RAD17 14525934 14611806 N/A experimental interaction detection HPRD
RAD17 ATR 10608806 11418864 14724280 20424596 27898060 stimulant N/A OmniPath
ATR RAD17 10608806 11418864 11687627 14500819 14724280 16885023 17110331 20424596 27898060 stimulant N/A OmniPath
RAD17 RAD9A 10884395 11572977 12578958 14611806 18082599 20424596 27898060 stimulant N/A OmniPath
ATM RAD17 10608806 11418864 11687627 14500819 18344987 27898060 stimulant N/A OmniPath

Visualization










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