GENE：SLC17A5
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | SLC17A5 |
| FullNmae | solute carrier family 17 member 5 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:10933 |
| EnsembleID | ENSG00000119899 |
| Uniprot | Q9NRA2 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| SLC17A5 | lysosomal_cd | 36341760 | 220 lysosome-dependent cell death genes. | retulator signature |
| SLC17A5 | lysosomal_cd | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
| SLC17A5 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| SLC17A5 | GO:0005351,GO:0005765,GO:0005765,GO:0005765,GO:0005829,GO:0005886,GO:0006811,GO:0006820,GO:0006865,GO:0009617,GO:0015136,GO:0015538,GO:0015739,GO:0016020,GO:0016323,GO:0022857,GO:0030672,GO:0034219,GO:0042874,GO:0042880,GO:1902600 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| SLC17A5 | hsa:26503 | path:hsa04142 | Lysosome - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | SLC17A5 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | SLC17A5 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA3 | SLC17A5 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXA1 | SLC17A5 | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | SLC17A5 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | SLC17A5 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | SLC17A5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | SLC17A5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | SLC17A5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | SLC17A5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | SLC17A5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | SLC17A5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | SLC17A5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GATA2 | SLC17A5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | SLC17A5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | SLC17A5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | SLC17A5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000237AF9 | SLC17A5 | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS0000122ED0 | SLC17A5 | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000003ABC4 | SLC17A5 | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000009262D | SLC17A5 | 18591254 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00001E0AEA | SLC17A5 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041FA2C | SLC17A5 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000018E72A | SLC17A5 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |