GENE:ABCC5
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | ABCC5 |
| FullNmae | ATP binding cassette subfamily C member 5 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:56 |
| EnsembleID | ENSG00000114770 |
| Uniprot | O15440 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| ABCC5 | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| ABCC5 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| ABCC5 | GO:0005524,GO:0005796,GO:0005886,GO:0005886,GO:0006805,GO:0006855,GO:0008514,GO:0008559,GO:0010008,GO:0015216,GO:0015232,GO:0015562,GO:0015865,GO:0016020,GO:0016020,GO:0016323,GO:0016323,GO:0016324,GO:0016887,GO:0022884,GO:0030213,GO:0034634,GO:0034775,GO:0035351,GO:0042626,GO:0042626,GO:0042908,GO:0042908,GO:0042910,GO:0043225,GO:0055085,GO:0055085,GO:0070730,GO:0070731,GO:0098656,GO:0098838,GO:0140115,GO:0150104,GO:1901505 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| ABCC5 | hsa:10057 | path:hsa01523 | Antifolate resistance - Homo sapiens (human) |
| ABCC5 | hsa:10057 | path:hsa02010 | ABC transporters - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | ABCC5 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| E2F4 | ABCC5 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ESR1 | ABCC5 | 18414489 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,chromatin immunoprecipitation assay | TFlink |
| ETS1 | ABCC5 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | ABCC5 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | ABCC5 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA3 | ABCC5 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXA1 | ABCC5 | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | ABCC5 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | ABCC5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | ABCC5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | ABCC5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | ABCC5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | ABCC5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | ABCC5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | ABCC5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000122ED0 | ABCC5 | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000033EBB8 | ABCC5 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00000BE495 | ABCC5 | 23592263 23622248 24398324 25416803 | mrna cleavage,inhibition | clip,clash | TarBase |
| URS0000083D87 | ABCC5 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000075A608 | ABCC5 | 23592263 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000753AD | ABCC5 | 23592263 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002971AB | ABCC5 | 23592263 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002394F5 | ABCC5 | 20371350 23592263 24398324 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00006097A6 | ABCC5 | 23592263 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002367FA | ABCC5 | 20371350 23592263 24398324 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000585553 | ABCC5 | 23592263 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000209F04 | ABCC5 | 23592263 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000014F13C | ABCC5 | 20371350 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00001919B0 | ABCC5 | 20371350 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00003AD2AA | ABCC5 | 20371350 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000547F6A | ABCC5 | 20371350 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C4DB5 | ABCC5 | 20371350 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00001012BC | ABCC5 | 20371350 21572407 22012620 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000435A77 | ABCC5 | 20371350 21572407 22012620 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003B59DF | ABCC5 | 20371350 21572407 22012620 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SERPINA3 | ABCC5 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| ESR1 | ABCC5 | 21182203 24234451 25348397 | association | pull down | ComPPI,IntAct |
| SHMT2 | ABCC5 | 25348397 | N/A | physical interaction | ComPPI |
| AK2 | ABCC5 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| NXF1 | ABCC5 | 25348397 | N/A | physical interaction | ComPPI |
| SMC2 | ABCC5 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| MOV10 | ABCC5 | 25348397 | N/A | physical interaction | ComPPI |
| RBP5 | ABCC5 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| H1-1 | ABCC5 | 24234451 30021884 | physical association | cross-linking study | IntAct |
| H1-5 | ABCC5 | 24234451 30021884 | physical association | cross-linking study | IntAct |
