Gene Information gene info

  1. Home

GENE：AFF4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol AFF4
FullNmae ALF transcription elongation factor 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17869
EnsembleID ENSG00000072364
Uniprot Q9UHB7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
AFF4 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
AFF4 GO:0000791,GO:0001650,GO:0005515,GO:0005654,GO:0005654,GO:0007286,GO:0008023,GO:0010468,GO:0032783,GO:0034976

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
AFF4 hsa:27125 path:hsa03250 Viral life cycle - HIV-1 - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AP2B1 AFF4 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 AFF4 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 AFF4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA AFF4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF AFF4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 AFF4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 AFF4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 AFF4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 AFF4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS AFF4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 AFF4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A AFF4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF AFF4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001EFEC1 AFF4 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00004505E4 AFF4 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS0000237AF9 AFF4 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00001B341F AFF4 20371350 22473208 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS00004B4B85 AFF4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000035CC3E AFF4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 AFF4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001D69F6 AFF4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002F5FEE AFF4 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 AFF4 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 AFF4 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001A4ABF AFF4 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003AFAD1 AFF4 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000048BA36 AFF4 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003003B4 AFF4 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000016914 AFF4 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA AFF4 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000453664 AFF4 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000E7139 AFF4 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A AFF4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000044FD7 AFF4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000029D9F1 AFF4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000040FA88 AFF4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001DE669 AFF4 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F AFF4 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 AFF4 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000065D58 AFF4 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 AFF4 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000236310 AFF4 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000018C928 AFF4 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D AFF4 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C AFF4 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 AFF4 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
AFF4 CDK9 25361965 interaction type N/A PTMCode2
CDK9 AFF4 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
GOLGA2 AFF4 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PBX2 AFF4 25348397 N/A physical interaction ComPPI
KEAP1 AFF4 25348397 N/A physical interaction ComPPI
SPP1 AFF4 25348397 N/A physical interaction ComPPI
SIAH1 AFF4 14525934 15459319 16189514 24234451 25348397 25416956 27898060 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct,OmniPath
HNRNPL AFF4 25348397 N/A physical interaction ComPPI
MDK AFF4 25348397 N/A physical interaction ComPPI
CTR9 AFF4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AFF1 AFF4 20153263 21729782 24234451 25348397 association affinity chromatography technology,anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SDCBP AFF4 24234451 25348397 26787460 N/A phage display ComPPI,IntAct
GRK5 AFF4 25348397 N/A physical interaction ComPPI
CCNT2 AFF4 21729782 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRAF2 AFF4 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
RXRB AFF4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AP2B1 AFF4 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ARRB2 AFF4 25348397 N/A physical interaction ComPPI
CCNT1 AFF4 12065898 14525934 20153263 21729782 24234451 25348397 association,physical association affinity chromatography technology,anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
ELL AFF4 21729782 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MED26 AFF4 15175163 21729782 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H3C1 AFF4 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
EDA AFF4 25348397 N/A physical interaction ComPPI
CDK9 AFF4 12065898 14525934 20153263 21729782 23455922 23602568 24234451 25348397 association affinity chromatography technology,anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,tandem affinity purification ComPPI,HPRD,IntAct
EAF2 AFF4 21729782 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EAF1 AFF4 21729782 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRIM25 AFF4 25348397 N/A physical interaction ComPPI
HECW2 AFF4 25348397 N/A physical interaction ComPPI
AFF4 MLLT1 14525934 15856011 20153263 21729782 24234451 25348397 association,physical association affinity chromatography technology,anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
AFF4 MLLT3 20153263 21729782 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AFF4 KMT2A 25348397 N/A physical interaction ComPPI
AFF4 ELL2 21729782 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AFF4 MED19 15175163 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AFF4 CDK15 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
AFF4 MTUS2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
AFF4 FAM9A 25348397 N/A physical interaction ComPPI
AFF4 HEXIM1 25348397 N/A physical interaction ComPPI
AFF4 ELL3 25348397 N/A physical interaction ComPPI
AFF4 DENND2D 25348397 N/A physical interaction ComPPI
AFF4 CNOT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AFF4 PIP4K2A 25348397 N/A physical interaction ComPPI
AFF4 CAMKV 25348397 N/A physical interaction ComPPI
AFF4 PES1 25348397 N/A physical interaction ComPPI
AFF4 RSBN1 25348397 N/A physical interaction ComPPI
AFF4 EPB41L5 25348397 N/A physical interaction ComPPI
AFF4 MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
AFF4 LRRK2 24234451 25348397 29513927 N/A protein array ComPPI,IntAct
STC2 AFF4 23746844 24234451 association chromatin immunoprecipitation assay IntAct
ANKRD37 AFF4 23746844 24234451 association chromatin immunoprecipitation assay IntAct
H2BC9 AFF4 24234451 30021884 physical association cross-linking study IntAct
H2AZ1 AFF4 24234451 30021884 physical association cross-linking study IntAct
H1-5 AFF4 24234451 30021884 physical association cross-linking study IntAct

Visualization










  Return