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GENE：ATP5MC1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ATP5MC1
FullNmae ATP synthase membrane subunit c locus 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:841
EnsembleID ENSG00000159199
Uniprot P05496

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ATP5MC1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ATP5MC1 GO:0000276,GO:0005515,GO:0005739,GO:0005743,GO:0005743,GO:0005753,GO:0005753,GO:0008289,GO:0015078,GO:0015986,GO:0015986,GO:1902600

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ATP5MC1 hsa:516 path:hsa00190 Oxidative phosphorylation - Homo sapiens (human)
ATP5MC1 hsa:516 path:hsa01100 Metabolic pathways - Homo sapiens (human)
ATP5MC1 hsa:516 path:hsa04714 Thermogenesis - Homo sapiens (human)
ATP5MC1 hsa:516 path:hsa05010 Alzheimer disease - Homo sapiens (human)
ATP5MC1 hsa:516 path:hsa05012 Parkinson disease - Homo sapiens (human)
ATP5MC1 hsa:516 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
ATP5MC1 hsa:516 path:hsa05016 Huntington disease - Homo sapiens (human)
ATP5MC1 hsa:516 path:hsa05020 Prion disease - Homo sapiens (human)
ATP5MC1 hsa:516 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
ATP5MC1 hsa:516 path:hsa05208 Chemical carcinogenesis - reactive oxygen species - Homo sapiens (human)
ATP5MC1 hsa:516 path:hsa05415 Diabetic cardiomyopathy - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ATP5MC1 TRIM69 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 ATP5MC1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 ATP5MC1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 ATP5MC1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ATP5MC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ATP5MC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ATP5MC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ATP5MC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ATP5MC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ATP5MC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001C770D ATP5MC1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001BCAC5 ATP5MC1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000032FC1A ATP5MC1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000D5FFC ATP5MC1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000F4AC3 ATP5MC1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5BAA ATP5MC1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000AA464 ATP5MC1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001067D1 ATP5MC1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000003575B ATP5MC1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002E0524 ATP5MC1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000043C1C3 ATP5MC1 23313552 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
LRFN4 ATP5MC1 25348397 N/A physical interaction ComPPI
ATP5MC1 TRIM69 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ATP5MC1 TNFSF11 25348397 N/A physical interaction ComPPI
ATP5MC1 BTN3A2 25348397 N/A physical interaction ComPPI
ATP5MC1 POMK 25348397 N/A physical interaction ComPPI
ATP5MC1 B4GALT3 25348397 N/A physical interaction ComPPI
ATP5MC1 BRINP2 25348397 N/A physical interaction ComPPI
ATP5MC1 FUT3 25348397 N/A physical interaction ComPPI
ATP5MC1 UBQLN1 25348397 N/A physical interaction ComPPI
ATP5MC1 ACTN2 24234451 25348397 25910212 physical association two hybrid array,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct

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