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GENE：GNA13

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GNA13
FullNmae G protein subunit alpha 13
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4381
EnsembleID ENSG00000120063
Uniprot Q14344

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GNA13 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GNA13 GO:0001569,GO:0001701,GO:0003924,GO:0005085,GO:0005515,GO:0005525,GO:0005634,GO:0005737,GO:0005829,GO:0005834,GO:0005886,GO:0005925,GO:0007165,GO:0007188,GO:0007189,GO:0007204,GO:0007266,GO:0008217,GO:0008360,GO:0010762,GO:0016020,GO:0030154,GO:0030168,GO:0031526,GO:0031584,GO:0031683,GO:0031752,GO:0042470,GO:0046872,GO:0051056,GO:0070062,GO:1904706,GO:1904753

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
GNA13 hsa:10672 path:hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human)
GNA13 hsa:10672 path:hsa04071 Sphingolipid signaling pathway - Homo sapiens (human)
GNA13 hsa:10672 path:hsa04072 Phospholipase D signaling pathway - Homo sapiens (human)
GNA13 hsa:10672 path:hsa04270 Vascular smooth muscle contraction - Homo sapiens (human)
GNA13 hsa:10672 path:hsa04371 Apelin signaling pathway - Homo sapiens (human)
GNA13 hsa:10672 path:hsa04611 Platelet activation - Homo sapiens (human)
GNA13 hsa:10672 path:hsa04730 Long-term depression - Homo sapiens (human)
GNA13 hsa:10672 path:hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human)
GNA13 hsa:10672 path:hsa04928 Parathyroid hormone synthesis, secretion and action - Homo sapiens (human)
GNA13 hsa:10672 path:hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human)
GNA13 hsa:10672 path:hsa05163 Human cytomegalovirus infection - Homo sapiens (human)
GNA13 hsa:10672 path:hsa05200 Pathways in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IRF8 GNA13 22096565 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
PRKAR2A GNA13 20005715 interaction type N/A PSP

Source Target Pmid Interactiontype Methods Database
AR GNA13 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA2 GNA13 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 GNA13 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 GNA13 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 GNA13 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA GNA13 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GNA13 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 GNA13 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 GNA13 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS GNA13 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A GNA13 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF GNA13 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 GNA13 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 GNA13 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 GNA13 N/A rna interference,inhibition experimental interaction detection miRSponge
URS0000338542 GNA13 18668040 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,experimental interaction detection TarBase
URS00002152A8 GNA13 20371350 22100165 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS0000065D58 GNA13 18668040 20371350 22100165 25416803 mrna cleavage,inhibition experimental interaction detection,clip TarBase
URS000003ABC4 GNA13 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000035CC3E GNA13 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001A405B GNA13 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000040780F GNA13 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000053B1E8 GNA13 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000250A40 GNA13 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00002CAE0C GNA13 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5BAA GNA13 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00001EE123 GNA13 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F GNA13 20371350 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00001DE669 GNA13 20371350 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00002D2333 GNA13 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00003D4175 GNA13 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000003E1A9 GNA13 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000008DA94 GNA13 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000535FDD GNA13 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002233F4 GNA13 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003538C1 GNA13 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004BC299 GNA13 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001123BD GNA13 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000023F8DA GNA13 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000001EB3 GNA13 25416803 25889182 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
PRKACA GNA13 22135298 phosphorylation N/A PhosphoSite
RIC8A GNA13 25361965 interaction type N/A PTMCode2
GNA13 RIC8A 25361965 interaction type N/A PTMCode2
ARHGEF12 GNA13 25361965 interaction type N/A PTMCode2
GNA13 ARHGEF12 25361965 interaction type N/A PTMCode2
PPP5C GNA13 25361965 interaction type N/A PTMCode2
GNA13 PPP5C 25361965 interaction type N/A PTMCode2
ARHGEF1 GNA13 25361965 interaction type N/A PTMCode2
GNA13 ARHGEF1 25361965 interaction type N/A PTMCode2
CXCR4 GNA13 25361965 interaction type N/A PTMCode2
GNA13 CXCR4 25361965 interaction type N/A PTMCode2
F2R GNA13 25361965 interaction type N/A PTMCode2
GNA13 F2R 25361965 interaction type N/A PTMCode2
GNA12 GNA13 25361965 interaction type N/A PTMCode2
GNA13 GNA12 25361965 interaction type N/A PTMCode2
ARHGEF11 GNA13 25361965 interaction type N/A PTMCode2
GNA13 ARHGEF11 25361965 interaction type N/A PTMCode2
AKAP3 GNA13 25361965 interaction type N/A PTMCode2
GNA13 AKAP3 25361965 interaction type N/A PTMCode2
S1PR3 GNA13 25361965 interaction type N/A PTMCode2
GNA13 S1PR3 25361965 interaction type N/A PTMCode2
S1PR4 GNA13 25361965 interaction type N/A PTMCode2
GNA13 S1PR4 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CDC73 GNA13 25348397 N/A physical interaction ComPPI
HOXB5 GNA13 25348397 N/A physical interaction ComPPI
RD3 GNA13 25348397 N/A physical interaction ComPPI
PTK2B GNA13 10821841 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
ARHGEF1 GNA13 12681510 14525934 20300064 24234451 25348397 9641916 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
CD81 GNA13 24234451 25348397 30024968 association anti bait coimmunoprecipitation ComPPI,IntAct
PRKCD GNA13 14525934 25348397 8824244 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
RGS16 GNA13 14525934 14634662 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PRKCE GNA13 14525934 25348397 8824244 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
GLI1 GNA13 25348397 N/A physical interaction ComPPI
MCF2 GNA13 11062019 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
PRKACA GNA13 12399457 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
ARHGEF12 GNA13 11094164 12515866 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
ARHGEF11 GNA13 10026210 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
AIP GNA13 25348397 N/A physical interaction ComPPI
NTRK1 GNA13 25348397 N/A physical interaction ComPPI
CDH1 GNA13 25348397 N/A two hybrid,physical interaction,in vitro ComPPI
S1PR1 GNA13 25348397 N/A physical interaction ComPPI
PVR GNA13 25348397 N/A physical interaction ComPPI
MAP3K5 GNA13 25348397 N/A physical interaction ComPPI
PRKCB GNA13 14525934 25348397 8824244 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PRKAR2A GNA13 25348397 N/A physical interaction ComPPI
AKAP3 GNA13 25348397 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI
F2R GNA13 10922491 14525934 23773523 24234451 25348397 8290554 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
CACYBP GNA13 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
GNA13 RDX 10816569 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
GNA13 PPP5C 12176367 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
GNA13 MTNR1A 10598579 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
GNA13 CDH2 11136230 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
GNA13 S1PR3 10488065 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
GNA13 GPR17 14525934 25348397 27898060 9092554 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
GNA13 TSHR 14525934 25348397 8552586 N/A experimental interaction detection,in vivo ComPPI,HPRD
GNA13 S1PR4 12767884 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
GNA13 S1PR2 10488065 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
GNA13 EDNRB 12135322 14525934 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
GNA13 RIC8A 12509430 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
GNA13 CTNNB1 11136230 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
GNA13 CXCR4 11994484 14525934 23773523 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
GNA13 DRD5 12623966 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
GNA13 TBXA2R 10395940 14525934 25348397 8290554 N/A experimental interaction detection,physical interaction ComPPI,HPRD
GNA13 ARHGEF28 25348397 N/A physical interaction ComPPI
GNA13 USP3 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GNA13 ELAVL1 25348397 N/A physical interaction ComPPI
GNA13 LRRK2 25348397 N/A physical interaction ComPPI
GNA13 GNG2 25348397 N/A physical interaction ComPPI
GNA13 AHR 25348397 N/A physical interaction ComPPI
GNA13 CXCR5 23773523 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
GNA13 CUL7 25348397 N/A physical interaction ComPPI
GNA13 CCDC8 25348397 N/A physical interaction ComPPI
GNA13 PHF19 25348397 N/A physical interaction ComPPI
GNA13 SLC25A41 25348397 N/A physical interaction ComPPI
GNA13 TAS2R7 25348397 N/A physical interaction ComPPI
GNA13 FYTTD1 25348397 N/A physical interaction ComPPI
GNA13 GNAI1 25348397 N/A physical interaction ComPPI
GNA13 CCR1 25348397 N/A physical interaction ComPPI
GNA13 TMEM185A 25348397 N/A physical interaction ComPPI
GNA13 MINDY2 25348397 N/A physical interaction ComPPI
GNA13 HERC2 25348397 N/A physical interaction ComPPI
GNA13 HERC2P3 25348397 N/A physical interaction ComPPI
GNA13 GNG3 25348397 N/A physical interaction ComPPI
GNA13 CYP2S1 25348397 N/A physical interaction ComPPI
GNA13 FANCE 25348397 N/A physical interaction ComPPI
GNA13 DUSP22 25348397 N/A physical interaction ComPPI
GNA13 PACC1 25348397 N/A physical interaction ComPPI
GNA13 TRIM25 25348397 N/A physical interaction ComPPI
GNA13 PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
GNG4 GNA13 25348397 N/A physical interaction ComPPI
GNA13 GNA12 10026210 14525934 N/A experimental interaction detection HPRD
GNA13 TGFBR1 14525934 15761153 N/A experimental interaction detection HPRD
AGTR1 GNA13 21289285 27898060 stimulant N/A OmniPath
PRKACA GNA13 12399457 27898060 N/A N/A OmniPath
FGFR1 GNA13 12399457 27898060 N/A N/A OmniPath
GNA13 RHOA 23450633 27898060 stimulant N/A OmniPath
F2R GNA13 10922491 16189514 21331223 22318735 22972936 23773523 27898060 8290554 stimulant N/A OmniPath
FZD3 GNA13 14977528 27898060 stimulant N/A OmniPath
LPAR2 GNA13 15856019 27898060 stimulant N/A OmniPath
GNA13 PTK2B 10821841 27898060 stimulant N/A OmniPath
EDNRA GNA13 10199825 27898060 stimulant N/A OmniPath
GNA13 ARHGEF1 12681510 14634662 27898060 9641915 9641916 stimulant N/A OmniPath
ARHGEF1 GNA13 12681510 14634662 27898060 9641915 9641916 inhibition,stimulant N/A OmniPath
GNA13 RDX 10816569 27898060 stimulant N/A OmniPath
S1PR3 GNA13 10488065 27898060 stimulant N/A OmniPath
F2RL3 GNA13 22318735 27898060 stimulant N/A OmniPath
S1PR2 GNA13 10488065 22863277 27898060 stimulant N/A OmniPath
LPAR3 GNA13 15856019 22863277 27898060 stimulant N/A OmniPath
NMBR GNA13 11313903 27898060 stimulant N/A OmniPath
LPAR1 GNA13 20331961 27898060 stimulant N/A OmniPath

Visualization










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