Gene Information gene info

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GENE：NFYA

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NFYA
FullNmae nuclear transcription factor Y subunit alpha
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7804
EnsembleID ENSG00000001167
Uniprot P23511

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NFYA mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NFYA ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NFYA autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NFYA GO:0000785,GO:0000976,GO:0000978,GO:0000978,GO:0000981,GO:0000981,GO:0003677,GO:0003700,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0006355,GO:0006357,GO:0006366,GO:0016602,GO:0016602,GO:0016602,GO:0032993,GO:0035065,GO:0045893,GO:0045944,GO:0048511,GO:0090575

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NFYA hsa:4800 path:hsa04612 Antigen processing and presentation - Homo sapiens (human)
NFYA hsa:4800 path:hsa05017 Spinocerebellar ataxia - Homo sapiens (human)
NFYA hsa:4800 path:hsa05152 Tuberculosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TGFBR2 NFYA 11744689 23180781 physical association affinity chromatography technology,electrophoretic mobility shift assay InnateDB
LGALS3 NFYA 16738336 23180781 physical association anti tag coimmunoprecipitation InnateDB
CCNB1 NFYA 16738336 23180781 physical association anti tag coimmunoprecipitation InnateDB
NFYA DHFR 16738336 23180781 physical association anti tag coimmunoprecipitation InnateDB
EGR1 NFYA 19374776 23180781 physical association anti tag coimmunoprecipitation InnateDB
NFYA EPHX1 15150264 23180781 physical association electrophoretic mobility supershift assay InnateDB
NFYA CEBPA 15150264 23180781 physical association anti tag coimmunoprecipitation InnateDB
NFYA COL11A1 12805369 23180781 physical association electrophoretic mobility supershift assay InnateDB
APP NFYA 21832049 23180781 physical association protein array InnateDB
NFYA PSMD10 23180781 25294684 physical association anti tag coimmunoprecipitation InnateDB
NFYA TOP2B 23180781 26518113 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR NFYA 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 NFYA 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 NFYA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA NFYA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NFYA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NFYA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NFYA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A NFYA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR NFYA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 NFYA N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000821E0 NFYA 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000B59A2 NFYA 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS0000170CF4 NFYA 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004DA9DB NFYA 23807165 25416803 mrna cleavage,inhibition array technology TarBase
URS0000065FDF NFYA 20371350 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000195F5B NFYA 20371350 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002ECEE4 NFYA 20371350 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 NFYA 20371350 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004BC299 NFYA 20371350 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000045DBD NFYA 20371350 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 NFYA 20371350 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000BA274 NFYA 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004B4B85 NFYA 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1A NFYA 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000CF1D2 NFYA 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000353492 NFYA 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003FBC84 NFYA 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000008B558 NFYA 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000544FF1 NFYA 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000555DA6 NFYA 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002F3336 NFYA 23313552 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
HMGA1 NFYA 25361965 interaction type N/A PTMCode2
NFYA HMGA1 25361965 interaction type N/A PTMCode2
ZHX2 NFYA 25361965 interaction type N/A PTMCode2
NFYA ZHX2 25361965 interaction type N/A PTMCode2
NFYB NFYA 25361965 interaction type N/A PTMCode2
NFYA NFYB 25361965 interaction type N/A PTMCode2
SRF NFYA 25361965 interaction type N/A PTMCode2
NFYA SRF 25361965 interaction type N/A PTMCode2
KAT2B NFYA 25361965 interaction type N/A PTMCode2
NFYA KAT2B 25361965 interaction type N/A PTMCode2
ZHX1 NFYA 25361965 interaction type N/A PTMCode2
NFYA ZHX1 25361965 interaction type N/A PTMCode2
NFYA ATF6 25361965 interaction type N/A PTMCode2
ATF6 NFYA 25361965 interaction type N/A PTMCode2
NFYA USF1 25361965 interaction type N/A PTMCode2
USF1 NFYA 25361965 interaction type N/A PTMCode2
TP53 NFYA 25361965 interaction type N/A PTMCode2
NFYA TP53 25361965 interaction type N/A PTMCode2
SPI1 NFYA 25361965 interaction type N/A PTMCode2
NFYA SPI1 25361965 interaction type N/A PTMCode2
POU2F1 NFYA 25361965 interaction type N/A PTMCode2
NFYA POU2F1 25361965 interaction type N/A PTMCode2
ZHX3 NFYA 25361965 interaction type N/A PTMCode2
NFYA ZHX3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
NFYB NFYA 14525934 15243141 16959611 23332751 24234451 25348397 25416956 8051128 association,physical association anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,x-ray crystallography,physical interaction,two hybrid array,biochemical,in vitro,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
TAF12 NFYA 25348397 N/A physical interaction ComPPI
GTF2A1 NFYA 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ZC3H10 NFYA 25348397 N/A physical interaction ComPPI
NR5A1 NFYA 12730328 14525934 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
APPBP2 NFYA 14525934 16189514 19060904 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SP1 NFYA 10393239 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
ELF1 NFYA 25348397 N/A physical interaction ComPPI
SPI1 NFYA 25348397 N/A physical interaction ComPPI
JUN NFYA 11903046 14525934 21565167 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
NFYA USF1 12791656 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
NFYA USF2 12791656 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
NFYA SRF 10571058 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
NFYA HMGA1 14525934 25348397 9388234 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
NFYA SRSF1 14525934 15243141 24234451 25348397 colocalization,association,physical association coimmunoprecipitation,experimental interaction detection,biochemical,imaging technique,in vitro,in vivo ComPPI,HPRD,IntAct
NFYA NFYC 15243141 20936779 23332751 24234451 25348397 association,physical association coimmunoprecipitation,x-ray crystallography,physical interaction,two hybrid pooling approach,biochemical,in vitro ComPPI,IntAct
NFYA ZHX3 12659632 14525934 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
NFYA ZHX1 10441475 10571058 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,OmniPath
NFYA ZHX2 12741956 14525934 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD,IntAct
NFYA BRCA1 11777930 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
NFYA CEBPA 14525934 15150264 25348397 27898060 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
NFYA CDK2 12857729 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
NFYA KPNB1 14525934 15964792 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
NFYA POU2F1 25348397 N/A in vivo ComPPI
NFYA ATF6 25348397 N/A physical interaction ComPPI
NFYA ATF6B 25348397 N/A physical interaction ComPPI
NFYA SREBF2 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
NFYA PWP1 25348397 N/A physical interaction ComPPI
NFYA PAPOLG 25348397 N/A physical interaction ComPPI
NFYA TP53 14525934 16959611 24234451 25348397 colocalization,association,physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,imaging technique ComPPI,HPRD,IntAct
NFYA TAF11 25348397 N/A physical interaction ComPPI
NFYA TAF6 25348397 N/A physical interaction ComPPI
NFYA EP300 25348397 N/A physical interaction ComPPI
NFYA HDAC1 25348397 N/A physical interaction ComPPI
NFYA APP 25348397 N/A physical interaction ComPPI
NFYA RPS6KA6 25348397 N/A physical interaction ComPPI
NFYA CCNA2 25348397 N/A physical interaction ComPPI
NFYA TP63 25348397 N/A physical interaction ComPPI
NFYA CDC25A 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
NFYA CSNK2A1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NFYA POGZ 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NFYA LUC7L2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NFYA SHMT2 25348397 N/A physical interaction ComPPI
NFYA MOV10 25348397 N/A physical interaction ComPPI
NFYA NXF1 25348397 N/A physical interaction ComPPI
NFYA ME1 25348397 N/A physical interaction ComPPI
NFYA UBE2D2 25348397 N/A physical interaction ComPPI
NFYA LASP1 25348397 N/A physical interaction ComPPI
NFYA HMGCS1 25348397 N/A physical interaction ComPPI
NFYA IRGQ 25348397 N/A physical interaction ComPPI
NFYA TCAF1 25348397 N/A physical interaction ComPPI
NFYA CREB1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
NFYA ESR1 25348397 N/A physical interaction ComPPI
NFYA ACTN4 25348397 N/A physical interaction ComPPI
NFYA FTO 25348397 N/A physical interaction ComPPI
NFYA TES 25348397 N/A physical interaction ComPPI
NFYA SERPINB1 25348397 N/A physical interaction ComPPI
NFYA UAP1 25348397 N/A physical interaction ComPPI
NFYA CHMP4A 25348397 N/A physical interaction ComPPI
NFYA CREBBP 25348397 N/A physical interaction ComPPI
NFYA KAT2B 16959611 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
PKM NFYA 25348397 N/A protein kinase assay ComPPI
ATF2 NFYA 25348397 N/A physical interaction ComPPI
EIF4EBP2 NFYA 25348397 N/A physical interaction ComPPI
NFYA NFYA 14525934 16959611 N/A experimental interaction detection HPRD
CDK2 NFYA 12857729 18669648 20068231 27898060 N/A N/A OmniPath
GLRX NFYA 19737086 27898060 stimulant N/A OmniPath
TP53 NFYA 15831478 16959611 27898060 inhibition N/A OmniPath
NFYA SP1 10393239 10446910 11022037 12427542 27898060 stimulant N/A OmniPath
NFYA PADI3 16671893 27898060 stimulant N/A OmniPath
RNF4 NFYA 15496512 27898060 stimulant N/A OmniPath

Visualization










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