GENE:NFYA
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | NFYA |
FullNmae | nuclear transcription factor Y subunit alpha |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:7804 |
EnsembleID | ENSG00000001167 |
Uniprot | P23511 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
NFYA | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
NFYA | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
NFYA | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
NFYA | GO:0000785,GO:0000976,GO:0000978,GO:0000978,GO:0000981,GO:0000981,GO:0003677,GO:0003700,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0006355,GO:0006357,GO:0006366,GO:0016602,GO:0016602,GO:0016602,GO:0032993,GO:0035065,GO:0045893,GO:0045944,GO:0048511,GO:0090575 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
NFYA | hsa:4800 | path:hsa04612 | Antigen processing and presentation - Homo sapiens (human) |
NFYA | hsa:4800 | path:hsa05017 | Spinocerebellar ataxia - Homo sapiens (human) |
NFYA | hsa:4800 | path:hsa05152 | Tuberculosis - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
TGFBR2 | NFYA | 11744689 23180781 | physical association | affinity chromatography technology,electrophoretic mobility shift assay | InnateDB |
LGALS3 | NFYA | 16738336 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
CCNB1 | NFYA | 16738336 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
NFYA | DHFR | 16738336 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
EGR1 | NFYA | 19374776 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
NFYA | EPHX1 | 15150264 23180781 | physical association | electrophoretic mobility supershift assay | InnateDB |
NFYA | CEBPA | 15150264 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
NFYA | COL11A1 | 12805369 23180781 | physical association | electrophoretic mobility supershift assay | InnateDB |
APP | NFYA | 21832049 23180781 | physical association | protein array | InnateDB |
NFYA | PSMD10 | 23180781 25294684 | physical association | anti tag coimmunoprecipitation | InnateDB |
NFYA | TOP2B | 23180781 26518113 | physical association | anti tag coimmunoprecipitation | InnateDB |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
AR | NFYA | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
ETS1 | NFYA | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
SMARCA4 | NFYA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | NFYA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | NFYA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | NFYA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXA1 | NFYA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | NFYA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
VDR | NFYA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F4 | NFYA | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS00000821E0 | NFYA | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
URS00000B59A2 | NFYA | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS0000170CF4 | NFYA | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00004DA9DB | NFYA | 23807165 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS0000065FDF | NFYA | 20371350 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000195F5B | NFYA | 20371350 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002ECEE4 | NFYA | 20371350 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000043D2C1 | NFYA | 20371350 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00004BC299 | NFYA | 20371350 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000045DBD | NFYA | 20371350 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000D2680 | NFYA | 20371350 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000BA274 | NFYA | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00004B4B85 | NFYA | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000016FD1A | NFYA | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000CF1D2 | NFYA | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000353492 | NFYA | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003FBC84 | NFYA | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000008B558 | NFYA | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000544FF1 | NFYA | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000555DA6 | NFYA | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002F3336 | NFYA | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
HMGA1 | NFYA | 25361965 | interaction type | N/A | PTMCode2 |
NFYA | HMGA1 | 25361965 | interaction type | N/A | PTMCode2 |
ZHX2 | NFYA | 25361965 | interaction type | N/A | PTMCode2 |
NFYA | ZHX2 | 25361965 | interaction type | N/A | PTMCode2 |
NFYB | NFYA | 25361965 | interaction type | N/A | PTMCode2 |
NFYA | NFYB | 25361965 | interaction type | N/A | PTMCode2 |
SRF | NFYA | 25361965 | interaction type | N/A | PTMCode2 |
NFYA | SRF | 25361965 | interaction type | N/A | PTMCode2 |
KAT2B | NFYA | 25361965 | interaction type | N/A | PTMCode2 |
NFYA | KAT2B | 25361965 | interaction type | N/A | PTMCode2 |
ZHX1 | NFYA | 25361965 | interaction type | N/A | PTMCode2 |
NFYA | ZHX1 | 25361965 | interaction type | N/A | PTMCode2 |
NFYA | ATF6 | 25361965 | interaction type | N/A | PTMCode2 |
ATF6 | NFYA | 25361965 | interaction type | N/A | PTMCode2 |
NFYA | USF1 | 25361965 | interaction type | N/A | PTMCode2 |
USF1 | NFYA | 25361965 | interaction type | N/A | PTMCode2 |
TP53 | NFYA | 25361965 | interaction type | N/A | PTMCode2 |
NFYA | TP53 | 25361965 | interaction type | N/A | PTMCode2 |
SPI1 | NFYA | 25361965 | interaction type | N/A | PTMCode2 |
NFYA | SPI1 | 25361965 | interaction type | N/A | PTMCode2 |
POU2F1 | NFYA | 25361965 | interaction type | N/A | PTMCode2 |
NFYA | POU2F1 | 25361965 | interaction type | N/A | PTMCode2 |
ZHX3 | NFYA | 25361965 | interaction type | N/A | PTMCode2 |
NFYA | ZHX3 | 25361965 | interaction type | N/A | PTMCode2 |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
NFYB | NFYA | 14525934 15243141 16959611 23332751 24234451 25348397 25416956 8051128 | association,physical association | anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,x-ray crystallography,physical interaction,two hybrid array,biochemical,in vitro,two hybrid prey pooling approach,validated two hybrid | ComPPI,HPRD,IntAct |
TAF12 | NFYA | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | NFYA | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
ZC3H10 | NFYA | 25348397 | N/A | physical interaction | ComPPI |
NR5A1 | NFYA | 12730328 14525934 25348397 27898060 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD,OmniPath |
APPBP2 | NFYA | 14525934 16189514 19060904 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
SP1 | NFYA | 10393239 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD |
ELF1 | NFYA | 25348397 | N/A | physical interaction | ComPPI |
SPI1 | NFYA | 25348397 | N/A | physical interaction | ComPPI |
JUN | NFYA | 11903046 14525934 21565167 25348397 27898060 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD,OmniPath |
NFYA | USF1 | 12791656 14525934 25348397 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
NFYA | USF2 | 12791656 14525934 25348397 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
NFYA | SRF | 10571058 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
NFYA | HMGA1 | 14525934 25348397 9388234 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
NFYA | SRSF1 | 14525934 15243141 24234451 25348397 | colocalization,association,physical association | coimmunoprecipitation,experimental interaction detection,biochemical,imaging technique,in vitro,in vivo | ComPPI,HPRD,IntAct |
NFYA | NFYC | 15243141 20936779 23332751 24234451 25348397 | association,physical association | coimmunoprecipitation,x-ray crystallography,physical interaction,two hybrid pooling approach,biochemical,in vitro | ComPPI,IntAct |
NFYA | ZHX3 | 12659632 14525934 25348397 | N/A | two hybrid,two hybrid | ComPPI,HPRD |
NFYA | ZHX1 | 10441475 10571058 14525934 25348397 27898060 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid | ComPPI,HPRD,OmniPath |
NFYA | ZHX2 | 12741956 14525934 24234451 25348397 | physical association | anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,in vivo,two hybrid | ComPPI,HPRD,IntAct |
NFYA | BRCA1 | 11777930 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
NFYA | CEBPA | 14525934 15150264 25348397 27898060 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD,OmniPath |
NFYA | CDK2 | 12857729 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
NFYA | KPNB1 | 14525934 15964792 25348397 27898060 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD,OmniPath |
NFYA | POU2F1 | 25348397 | N/A | in vivo | ComPPI |
NFYA | ATF6 | 25348397 | N/A | physical interaction | ComPPI |
NFYA | ATF6B | 25348397 | N/A | physical interaction | ComPPI |
NFYA | SREBF2 | 20936779 24234451 25348397 | physical association | physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach | ComPPI,IntAct |
NFYA | PWP1 | 25348397 | N/A | physical interaction | ComPPI |
NFYA | PAPOLG | 25348397 | N/A | physical interaction | ComPPI |
NFYA | TP53 | 14525934 16959611 24234451 25348397 | colocalization,association,physical association | anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,imaging technique | ComPPI,HPRD,IntAct |
NFYA | TAF11 | 25348397 | N/A | physical interaction | ComPPI |
NFYA | TAF6 | 25348397 | N/A | physical interaction | ComPPI |
NFYA | EP300 | 25348397 | N/A | physical interaction | ComPPI |
NFYA | HDAC1 | 25348397 | N/A | physical interaction | ComPPI |
NFYA | APP | 25348397 | N/A | physical interaction | ComPPI |
NFYA | RPS6KA6 | 25348397 | N/A | physical interaction | ComPPI |
NFYA | CCNA2 | 25348397 | N/A | physical interaction | ComPPI |
NFYA | TP63 | 25348397 | N/A | physical interaction | ComPPI |
NFYA | CDC25A | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
NFYA | CSNK2A1 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
NFYA | POGZ | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
NFYA | LUC7L2 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
NFYA | SHMT2 | 25348397 | N/A | physical interaction | ComPPI |
NFYA | MOV10 | 25348397 | N/A | physical interaction | ComPPI |
NFYA | NXF1 | 25348397 | N/A | physical interaction | ComPPI |
NFYA | ME1 | 25348397 | N/A | physical interaction | ComPPI |
NFYA | UBE2D2 | 25348397 | N/A | physical interaction | ComPPI |
NFYA | LASP1 | 25348397 | N/A | physical interaction | ComPPI |
NFYA | HMGCS1 | 25348397 | N/A | physical interaction | ComPPI |
NFYA | IRGQ | 25348397 | N/A | physical interaction | ComPPI |
NFYA | TCAF1 | 25348397 | N/A | physical interaction | ComPPI |
NFYA | CREB1 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
NFYA | ESR1 | 25348397 | N/A | physical interaction | ComPPI |
NFYA | ACTN4 | 25348397 | N/A | physical interaction | ComPPI |
NFYA | FTO | 25348397 | N/A | physical interaction | ComPPI |
NFYA | TES | 25348397 | N/A | physical interaction | ComPPI |
NFYA | SERPINB1 | 25348397 | N/A | physical interaction | ComPPI |
NFYA | UAP1 | 25348397 | N/A | physical interaction | ComPPI |
NFYA | CHMP4A | 25348397 | N/A | physical interaction | ComPPI |
NFYA | CREBBP | 25348397 | N/A | physical interaction | ComPPI |
NFYA | KAT2B | 16959611 24234451 25348397 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
PKM | NFYA | 25348397 | N/A | protein kinase assay | ComPPI |
ATF2 | NFYA | 25348397 | N/A | physical interaction | ComPPI |
EIF4EBP2 | NFYA | 25348397 | N/A | physical interaction | ComPPI |
NFYA | NFYA | 14525934 16959611 | N/A | experimental interaction detection | HPRD |
CDK2 | NFYA | 12857729 18669648 20068231 27898060 | N/A | N/A | OmniPath |
GLRX | NFYA | 19737086 27898060 | stimulant | N/A | OmniPath |
TP53 | NFYA | 15831478 16959611 27898060 | inhibition | N/A | OmniPath |
NFYA | SP1 | 10393239 10446910 11022037 12427542 27898060 | stimulant | N/A | OmniPath |
NFYA | PADI3 | 16671893 27898060 | stimulant | N/A | OmniPath |
RNF4 | NFYA | 15496512 27898060 | stimulant | N/A | OmniPath |