Gene Information gene info

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GENE：PRDX4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PRDX4
FullNmae peroxiredoxin 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17169
EnsembleID ENSG00000123131
Uniprot Q13162

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PRDX4 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PRDX4 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PRDX4 GO:0005515,GO:0005576,GO:0005634,GO:0005783,GO:0005829,GO:0006979,GO:0007252,GO:0007283,GO:0008379,GO:0008584,GO:0022417,GO:0030198,GO:0033554,GO:0034774,GO:0042744,GO:0042802,GO:0045454,GO:0060090,GO:0070062,GO:0098869,GO:0140313,GO:1904813,GO:2000255

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
LBP PRDX4 21988832 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB
BMI1 PRDX4 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
YBX1 PRDX4 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 PRDX4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PRDX4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PRDX4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PRDX4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PRDX4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PRDX4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 PRDX4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00004E008F PRDX4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 PRDX4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE PRDX4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000153377 PRDX4 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
SULT2A1 PRDX4 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NPM1 PRDX4 25348397 N/A physical interaction ComPPI
UBL4A PRDX4 25348397 N/A physical interaction ComPPI
GABARAPL2 PRDX4 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
BMI1 PRDX4 25348397 N/A physical interaction ComPPI
KEAP1 PRDX4 25348397 N/A physical interaction ComPPI
DUSP23 PRDX4 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TTF2 PRDX4 12927788 14525934 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
MAP4K2 PRDX4 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
JUN PRDX4 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
EP300 PRDX4 21988832 24234451 25348397 physical association two hybrid ComPPI,IntAct
CUL3 PRDX4 25348397 N/A physical interaction ComPPI
PLG PRDX4 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PDIA3 PRDX4 21057456 24234451 25348397 oxidoreductase activity electron transfer reaction enzymatic study ComPPI,IntAct
TUBG1 PRDX4 25348397 N/A physical interaction ComPPI
PDIA6 PRDX4 21057456 24234451 25348397 colocalization,oxidoreductase activity electron transfer reaction enzymatic study ComPPI,IntAct
UBC PRDX4 25348397 N/A physical interaction ComPPI
NTRK1 PRDX4 25348397 N/A physical interaction ComPPI
ENO1 PRDX4 25348397 N/A physical interaction ComPPI
CANX PRDX4 17644091 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
VTN PRDX4 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TLN1 PRDX4 25348397 N/A physical interaction ComPPI
CSNK1E PRDX4 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
P4HB PRDX4 21057456 24234451 25348397 oxidoreductase activity electron transfer reaction enzymatic study ComPPI,IntAct
PRDX4 PRDX1 14525934 21988832 24234451 25348397 27898060 9388242 physical association two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct,OmniPath
PRDX4 SUMO4 14525934 16236267 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PRDX4 TERF1 25348397 N/A physical interaction ComPPI
PRDX4 TERF2 25348397 N/A physical interaction ComPPI
PRDX4 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRDX4 MRPL58 20186120 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRDX4 HDAC5 25348397 N/A physical interaction ComPPI
PRDX4 HDAC6 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PRDX4 NR4A1 21900206 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PRDX4 SIRT7 25348397 N/A physical interaction ComPPI
PRDX4 CUL2 25348397 N/A physical interaction ComPPI
PRDX4 LPA 25348397 N/A physical interaction ComPPI
PRDX4 CLIC1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PRDX4 ALG12 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PRDX4 A1BG 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PRDX4 APOB 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PRDX4 CYP27A1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PRDX4 CFHR1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PRDX4 LBP 21988832 24234451 25348397 colocalization,physical association anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction,confocal microscopy ComPPI,IntAct
PRDX4 MT-CO1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PRDX4 PRDX2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PRDX4 CFHR3 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PRDX4 PRDX3 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PRDX4 RCHY1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PRDX4 TBXA2R 17644091 24234451 25348397 27898060 physical association anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction ComPPI,IntAct,OmniPath
PRDX4 HUWE1 25348397 N/A physical interaction ComPPI
PRDX4 MOV10 25348397 N/A physical interaction ComPPI
PRDX4 NXF1 25348397 N/A physical interaction ComPPI
PRDX4 EED 25348397 N/A physical interaction ComPPI
PRDX4 EWSR1 25348397 N/A physical interaction ComPPI
PRDX4 TCTN1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PRDX4 CRY1 25348397 N/A physical interaction ComPPI
PRDX4 RC3H1 25348397 N/A physical interaction ComPPI
PRDX4 ATOH1 25348397 N/A physical interaction ComPPI
PRDX4 PTP4A2 25348397 N/A physical interaction ComPPI
PRDX4 COX15 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PRDX4 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PRDX4 TRIM25 25348397 N/A physical interaction ComPPI
PRDX4 PPP2R2B 19156129 24234451 25348397 association pull down ComPPI,IntAct
PRDX4 ESR2 21182203 24234451 25348397 association affinity chromatography technology ComPPI,IntAct
PRDX4 GABARAPL1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PRDX4 GABARAP 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PRDX4 TXNDC5 21057456 24234451 25348397 oxidoreductase activity electron transfer reaction enzymatic study ComPPI,IntAct
ZNF593 PRDX4 25348397 N/A physical interaction ComPPI
PRDX4 PRDX4 14525934 9388242 N/A experimental interaction detection,two hybrid HPRD
FADD PRDX4 24234451 30561431 association virotrap IntAct
LBP PRDX4 21988832 27898060 N/A N/A OmniPath
KDM2B PRDX4 18838535 27898060 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009B4749 PRDX4 27087310 direct interaction,inhibition N/A NPInter

Visualization










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