Gene Information gene info

  1. Home

GENE：GEMIN4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GEMIN4
FullNmae gem nuclear organelle associated protein 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:15717
EnsembleID ENSG00000179409
Uniprot P57678

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GEMIN4 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GEMIN4 GO:0000387,GO:0000387,GO:0000387,GO:0005515,GO:0005654,GO:0005730,GO:0005737,GO:0005829,GO:0005829,GO:0006364,GO:0015030,GO:0016020,GO:0016604,GO:0030532,GO:0032797,GO:0032797,GO:0032797,GO:0034719,GO:0043021,GO:0070062,GO:0097504

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GEMIN4 PIAS3 12869526 23180781 physical association two hybrid InnateDB
GEMIN4 SPRY1 12869526 23180781 physical association two hybrid InnateDB
GEMIN4 NFKBIL1 17353931 23180781 physical association anti tag coimmunoprecipitation,affinity technology InnateDB
LGALS1 GEMIN4 11522829 23180781 physical association two hybrid InnateDB
BMI1 GEMIN4 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 GEMIN4 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 GEMIN4 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 GEMIN4 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
E2F4 GEMIN4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 GEMIN4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000148B91 GEMIN4 21172025 rna interference,inhibition northern blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS0000148B91 GEMIN4 19536157 21172025 25416803 mrna cleavage,inhibition northern blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS00000AA464 GEMIN4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE GEMIN4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001597DC GEMIN4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001799A3 GEMIN4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000355E82 GEMIN4 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001A6D0C GEMIN4 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075A760 GEMIN4 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 GEMIN4 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000040FA88 GEMIN4 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000553F51 GEMIN4 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D GEMIN4 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000006372A GEMIN4 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000043C1C3 GEMIN4 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003D4175 GEMIN4 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003FBC84 GEMIN4 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC4BD GEMIN4 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000100748 GEMIN4 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SNRPD1 GEMIN4 25361965 interaction type N/A PTMCode2
GEMIN4 SNRPD1 25361965 interaction type N/A PTMCode2
GEMIN5 GEMIN4 25361965 interaction type N/A PTMCode2
GEMIN4 GEMIN5 25361965 interaction type N/A PTMCode2
CALCOCO2 GEMIN4 25361965 interaction type N/A PTMCode2
GEMIN4 CALCOCO2 25361965 interaction type N/A PTMCode2
GEMIN4 SNRPD2 25361965 interaction type N/A PTMCode2
SNRPD2 GEMIN4 25361965 interaction type N/A PTMCode2
GEMIN4 DDX20 25361965 interaction type N/A PTMCode2
DDX20 GEMIN4 25361965 interaction type N/A PTMCode2
GEMIN4 SMN1 25361965 interaction type N/A PTMCode2
SMN1 GEMIN4 25361965 interaction type N/A PTMCode2
GEMIN6 GEMIN4 25361965 interaction type N/A PTMCode2
GEMIN4 GEMIN6 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
KRTAP9-2 GEMIN4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SNRPB GEMIN4 10725331 14525934 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,pull down,physical interaction ComPPI,HPRD,IntAct
LGALS3 GEMIN4 11522829 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
SNW1 GEMIN4 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC5L GEMIN4 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SPRY1 GEMIN4 12869526 14525934 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
CD2BP2 GEMIN4 25348397 N/A physical interaction ComPPI
CRYAB GEMIN4 25348397 N/A physical interaction ComPPI
KRTAP2-3 GEMIN4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ALPP GEMIN4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SNRPF GEMIN4 25348397 N/A physical interaction ComPPI
UBL4A GEMIN4 25348397 N/A physical interaction ComPPI
TP53BP1 GEMIN4 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
SNRPG GEMIN4 25348397 N/A physical interaction ComPPI
CCDC185 GEMIN4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BMI1 GEMIN4 25348397 N/A physical interaction ComPPI
SMN1 GEMIN4 11714716 19928837 23752268 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
GLYR1 GEMIN4 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NPPB GEMIN4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEMIN6 GEMIN4 25348397 N/A physical interaction ComPPI
GEMIN7 GEMIN4 25348397 N/A physical interaction ComPPI
PTPN9 GEMIN4 25348397 N/A physical interaction ComPPI
DDX20 GEMIN4 10725331 11714716 14525934 23752268 24234451 25348397 association,physical association anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,filter binding,pull down,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,HPRD,IntAct
SNRNP70 GEMIN4 25348397 N/A physical interaction ComPPI
PPP4C GEMIN4 25348397 N/A physical interaction ComPPI
JUN GEMIN4 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
DHX9 GEMIN4 11149922 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
OPRM1 GEMIN4 25348397 N/A physical interaction ComPPI
PNKP GEMIN4 25348397 N/A physical interaction ComPPI
GSK3B GEMIN4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TAP1 GEMIN4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NTRK1 GEMIN4 25348397 N/A physical interaction ComPPI
F2RL1 GEMIN4 25348397 N/A physical interaction ComPPI
YBX1 GEMIN4 23986595 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
ILK GEMIN4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RPA1 GEMIN4 25348397 N/A physical interaction ComPPI
MYC GEMIN4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SQSTM1 GEMIN4 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GIPC1 GEMIN4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
GRK5 GEMIN4 25348397 N/A physical interaction ComPPI
RPA2 GEMIN4 25348397 N/A physical interaction ComPPI
RPA3 GEMIN4 25348397 N/A physical interaction ComPPI
BRF2 GEMIN4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
GEMIN2 GEMIN4 25348397 N/A physical interaction ComPPI
GEMIN5 GEMIN4 11714716 14525934 24234451 25348397 26496610 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction ComPPI,HPRD,IntAct
EGFR GEMIN4 25348397 N/A physical interaction ComPPI
SPG21 GEMIN4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STRAP GEMIN4 25348397 N/A physical interaction ComPPI
RIPK2 GEMIN4 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
HDAC11 GEMIN4 23752268 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NUFIP1 GEMIN4 25348397 N/A physical interaction ComPPI
NFKB2 GEMIN4 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
BARD1 GEMIN4 25348397 N/A physical interaction ComPPI
GAR1 GEMIN4 25348397 N/A physical interaction ComPPI
RAD51D GEMIN4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PIAS3 GEMIN4 12869526 14525934 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SRP9 GEMIN4 25348397 N/A physical interaction ComPPI
MIB1 GEMIN4 25348397 N/A physical interaction ComPPI
CDK4 GEMIN4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
HR GEMIN4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GIGYF2 GEMIN4 25348397 N/A physical interaction ComPPI
PARK7 GEMIN4 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PSMB1 GEMIN4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DMPK GEMIN4 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PPP4R2 GEMIN4 25348397 N/A physical interaction ComPPI
LY86 GEMIN4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IQCB1 GEMIN4 21565611 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNPS1 GEMIN4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CALCOCO2 GEMIN4 12869526 14525934 25348397 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
S1PR4 GEMIN4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TOP1 GEMIN4 25348397 N/A physical interaction ComPPI
AGO2 GEMIN4 17932509 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AGO1 GEMIN4 17932509 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
DICER1 GEMIN4 23752268 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RRP1B GEMIN4 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
FIBP GEMIN4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TSC22D1 GEMIN4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PTGER3 GEMIN4 25348397 N/A physical interaction ComPPI
CFP GEMIN4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FBXL12 GEMIN4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SNRPE GEMIN4 25348397 N/A physical interaction ComPPI
SRP54 GEMIN4 25348397 N/A physical interaction ComPPI
LGALS1 GEMIN4 11522829 14525934 25348397 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
USP2 GEMIN4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SNRPN GEMIN4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SRRT GEMIN4 12869526 14525934 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
FLAD1 GEMIN4 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
FBL GEMIN4 25348397 N/A physical interaction ComPPI
SIRT7 GEMIN4 25348397 N/A physical interaction ComPPI
MAP3K1 GEMIN4 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
SLX1A GEMIN4 19596235 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PTP4A3 GEMIN4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
P2RY12 GEMIN4 25348397 N/A physical interaction ComPPI
MORC4 GEMIN4 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
UXS1 GEMIN4 25348397 N/A physical interaction ComPPI
SNRPGP15 GEMIN4 25348397 N/A physical interaction ComPPI
CCT3 GEMIN4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEMIN4 NFKBIL1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
GEMIN4 CLN3 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GEMIN4 ALDH3A2 25348397 N/A physical interaction ComPPI
GEMIN4 NSD2 25348397 N/A physical interaction ComPPI
GEMIN4 USP9X 25348397 N/A physical interaction ComPPI
GEMIN4 SIGLECL1 25348397 N/A physical interaction ComPPI
GEMIN4 FZD10 25348397 N/A physical interaction ComPPI
GEMIN4 WRAP73 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
GEMIN4 UFC1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEMIN4 ZNF326 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEMIN4 KRTAP13-4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEMIN4 PTCD1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEMIN4 CERCAM 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEMIN4 KANK2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEMIN4 ZNF35 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEMIN4 KRTAP15-1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEMIN4 KRTAP13-2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEMIN4 PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
GEMIN4 SNRPD2 10725331 14525934 N/A experimental interaction detection HPRD
GEMIN4 SNRPD1 10725331 14525934 N/A experimental interaction detection HPRD
GEMIN4 STXBP2 11748230 14525934 N/A experimental interaction detection HPRD
STXBP3 GEMIN4 12065586 14525934 N/A experimental interaction detection HPRD
GEMIN4 PIAS3 12869526 21988832 27898060 N/A N/A OmniPath
SPRY1 GEMIN4 12869526 21988832 27898060 N/A N/A OmniPath

Visualization










  Return