Gene Information gene info

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GENE：P4HA2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol P4HA2
FullNmae prolyl 4-hydroxylase subunit alpha 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8547
EnsembleID ENSG00000072682
Uniprot O15460

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
P4HA2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
P4HA2 GO:0004656,GO:0004656,GO:0005506,GO:0005654,GO:0005783,GO:0005783,GO:0005788,GO:0005829,GO:0009055,GO:0018401,GO:0022900,GO:0031418,GO:0043231

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
P4HA2 hsa:8974 path:hsa00330 Arginine and proline metabolism - Homo sapiens (human)
P4HA2 hsa:8974 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR P4HA2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 P4HA2 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 P4HA2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 P4HA2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 P4HA2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 P4HA2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C P4HA2 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 P4HA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA P4HA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF P4HA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 P4HA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS P4HA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HIF1A P4HA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A P4HA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR P4HA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 P4HA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000065D58 P4HA2 18668040 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,experimental interaction detection TarBase

Source Target Pmid Interactiontype Methods Database
PPL P4HA2 25348397 N/A physical interaction ComPPI
FHL3 P4HA2 25348397 N/A physical interaction ComPPI
BAG3 P4HA2 25348397 N/A physical interaction ComPPI
TRIM32 P4HA2 25348397 N/A physical interaction ComPPI
FIP1L1 P4HA2 25348397 N/A physical interaction ComPPI
ARAF P4HA2 25348397 N/A physical interaction ComPPI
PIK3CB P4HA2 25348397 N/A physical interaction ComPPI
IRS4 P4HA2 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
P4HB P4HA2 14525934 24234451 25348397 26186194 26344197 27898060 30021884 7753822 physical association cross-linking study,experimental interaction detection,physical interaction,in vivo,inference by socio-affinity scoring ComPPI,HPRD,IntAct,OmniPath
CHTF18 P4HA2 25348397 N/A physical interaction ComPPI
DSCC1 P4HA2 25348397 N/A physical interaction ComPPI
POLD2 P4HA2 25348397 N/A physical interaction ComPPI
ERF P4HA2 25348397 N/A physical interaction ComPPI
PRRC2A P4HA2 14525934 14667819 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
TSC2 P4HA2 25348397 N/A physical interaction ComPPI
MELK P4HA2 25348397 N/A physical interaction ComPPI
CCT7 P4HA2 25348397 N/A physical interaction ComPPI
RAVER1 P4HA2 25348397 N/A physical interaction ComPPI
TAF1C P4HA2 25348397 N/A physical interaction ComPPI
ARVCF P4HA2 25348397 N/A physical interaction ComPPI
UTP14A P4HA2 25348397 N/A physical interaction ComPPI
CREB3 P4HA2 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
FOXF2 P4HA2 25348397 N/A physical interaction ComPPI
H2AX P4HA2 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COL1A1 P4HA2 25348397 N/A physical interaction ComPPI
ATXN2 P4HA2 25348397 N/A physical interaction ComPPI
STUB1 P4HA2 25348397 N/A physical interaction ComPPI
CLNK P4HA2 25348397 N/A physical interaction ComPPI
PKN3 P4HA2 25348397 N/A physical interaction ComPPI
TSC22D4 P4HA2 25348397 N/A physical interaction ComPPI
EIF4E2 P4HA2 25348397 N/A physical interaction ComPPI
CPSF3 P4HA2 25348397 N/A physical interaction ComPPI
NEK7 P4HA2 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
SCYL1 P4HA2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
P4HA2 DMWD 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
P4HA2 TNS4 25348397 N/A physical interaction ComPPI
P4HA2 SEC16A 25348397 N/A physical interaction ComPPI
P4HA2 KIF7 25348397 N/A physical interaction ComPPI
P4HA2 WDR33 25348397 N/A physical interaction ComPPI
P4HA2 ATG4D 25348397 N/A physical interaction ComPPI
P4HA2 IQSEC1 25348397 N/A physical interaction ComPPI
P4HA2 CCT2 25348397 N/A physical interaction ComPPI
P4HA2 FAAP100 25348397 N/A physical interaction ComPPI
P4HA2 DISC1 25348397 N/A physical interaction ComPPI
P4HA2 GTSE1 25348397 N/A physical interaction ComPPI
P4HA2 SAV1 25348397 N/A physical interaction ComPPI
P4HA2 SMG8 25348397 N/A physical interaction ComPPI
P4HA2 CCT6A 25348397 N/A physical interaction ComPPI
P4HA2 POLR3B 25348397 N/A physical interaction ComPPI
P4HA2 CCT3 25348397 N/A physical interaction ComPPI
P4HA2 WDR62 25348397 N/A physical interaction ComPPI
P4HA2 RECQL4 25348397 N/A physical interaction ComPPI
P4HA2 RICTOR 25348397 N/A physical interaction ComPPI
P4HA2 TRIM65 25348397 N/A physical interaction ComPPI
P4HA2 TRMT1 25348397 N/A physical interaction ComPPI
P4HA2 BCAR1 24234451 25348397 28007913 association anti bait coimmunoprecipitation ComPPI,IntAct
P4HA2 P4HA1 24234451 30021884 physical association cross-linking study IntAct
P4HA2 PPIC 24234451 30021884 physical association cross-linking study IntAct
P4HA2 RPS13 24234451 30021884 physical association cross-linking study IntAct
P4HA2 UTP3 24234451 30021884 physical association cross-linking study IntAct
P4HA2 MORC2 24234451 30021884 physical association cross-linking study IntAct
TP53 P4HA2 16917063 27898060 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00008C00C7 P4HA2 27087310 direct interaction,inhibition N/A NPInter

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