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GENE：PGRMC1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PGRMC1
FullNmae progesterone receptor membrane component 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16090
EnsembleID ENSG00000101856
Uniprot O00264

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PGRMC1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PGRMC1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PGRMC1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PGRMC1 GO:0001540,GO:0005496,GO:0005515,GO:0005576,GO:0005741,GO:0005783,GO:0005783,GO:0005886,GO:0006783,GO:0012505,GO:0016020,GO:0016020,GO:0020037,GO:0020037,GO:0030868,GO:0035579,GO:0042803,GO:0043005,GO:0043025,GO:0044297,GO:0045202,GO:0046872,GO:1903078

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PGRMC1 hsa:10857 path:hsa04080 Neuroactive ligand-receptor interaction - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PGRMC1 CEBPD 21072181 23180781 physical association anti tag coimmunoprecipitation InnateDB
ADRB2 PGRMC1 23180781 23798571 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR PGRMC1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 PGRMC1 11799066 18971253 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 PGRMC1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TRIM28 PGRMC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TFAP2A PGRMC1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000324096 PGRMC1 N/A rna interference,inhibition experimental interaction detection miRSponge
URS0000324096 PGRMC1 18668040 21572407 25416803 mrna cleavage,inhibition experimental interaction detection,clip TarBase
URS0000122ED0 PGRMC1 19088304 21572407 22492871 25416803 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS00000AD002 PGRMC1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002C0FCB PGRMC1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000C85B2 PGRMC1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000031E12 PGRMC1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000A07C1 PGRMC1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000000B1C9 PGRMC1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000029979D PGRMC1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000237CBD PGRMC1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004CD810 PGRMC1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000070B1D PGRMC1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000032EF64 PGRMC1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000032FC1A PGRMC1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00005CE113 PGRMC1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000048D44E PGRMC1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 PGRMC1 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CIAO1 PGRMC1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EIF1B PGRMC1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
GET3 PGRMC1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PAK2 PGRMC1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SGTB PGRMC1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBL4A PGRMC1 25348397 N/A physical interaction ComPPI
TRAF6 PGRMC1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
BIK PGRMC1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KASH5 PGRMC1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PTPRO PGRMC1 25348397 N/A physical interaction ComPPI
COPS5 PGRMC1 25348397 N/A physical interaction ComPPI
CUL3 PGRMC1 25348397 N/A physical interaction ComPPI
ABCD3 PGRMC1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CANX PGRMC1 24234451 25348397 29568061 association pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PTPN1 PGRMC1 25348397 N/A physical interaction ComPPI
RPA1 PGRMC1 25348397 N/A physical interaction ComPPI
HNRNPU PGRMC1 25348397 N/A physical interaction ComPPI
PTPN5 PGRMC1 24234451 25348397 28330616 association pull down ComPPI,IntAct
CFTR PGRMC1 25348397 N/A physical interaction ComPPI
VDAC1 PGRMC1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
FECH PGRMC1 24234451 25348397 27599036 enzymatic reaction,physical association anti tag coimmunoprecipitation,pull down,physical interaction,enzymatic study ComPPI,IntAct
ITGB1BP1 PGRMC1 25348397 N/A physical interaction ComPPI
RPA2 PGRMC1 25348397 N/A physical interaction ComPPI
RPA3 PGRMC1 25348397 N/A physical interaction ComPPI
ADRB2 PGRMC1 25348397 N/A physical interaction ComPPI
BCAP31 PGRMC1 25348397 N/A physical interaction ComPPI
EGFR PGRMC1 25348397 N/A physical interaction ComPPI
VHL PGRMC1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TIMP2 PGRMC1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
MED23 PGRMC1 25348397 N/A physical interaction ComPPI
PTPRE PGRMC1 25348397 N/A physical interaction ComPPI
CUL7 PGRMC1 25348397 N/A physical interaction ComPPI
SRSF3 PGRMC1 25348397 N/A physical interaction ComPPI
FKBP8 PGRMC1 25348397 N/A physical interaction ComPPI
DUSP22 PGRMC1 25348397 N/A physical interaction ComPPI
TRIM25 PGRMC1 25348397 N/A physical interaction ComPPI
HNRNPH1 PGRMC1 25348397 N/A physical interaction ComPPI
SCAP PGRMC1 14525934 15782218 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
INSIG1 PGRMC1 25348397 N/A physical interaction ComPPI
MTNR1A PGRMC1 14525934 17215244 24234451 25348397 26514267 association experimental interaction detection,physical interaction,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
CAMLG PGRMC1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CENPU PGRMC1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TGOLN2 PGRMC1 24234451 25348397 29568061 association pull down,proximity-dependent biotin identification ComPPI,IntAct
RPS20 PGRMC1 25348397 N/A physical interaction ComPPI
IKBKE PGRMC1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
NCDN PGRMC1 25348397 N/A physical interaction ComPPI
MPG PGRMC1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PGRMC1 EFHD1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PGRMC1 DNAAF5 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PGRMC1 SFXN1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PGRMC1 DDOST 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PGRMC1 RNF13 25348397 N/A physical interaction ComPPI
PGRMC1 SPCS2 25348397 N/A physical interaction ComPPI
PGRMC1 ILF3 25348397 N/A physical interaction ComPPI
PGRMC1 GCN1 25348397 N/A physical interaction ComPPI
PGRMC1 CYP3A4 21081644 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,physical interaction,confocal microscopy ComPPI,IntAct
PGRMC1 CYP2C8 21081644 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PGRMC1 POR 21081644 24234451 25348397 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,confocal microscopy ComPPI,IntAct
PGRMC1 CREB3L1 25348397 N/A physical interaction ComPPI
PGRMC1 CCDC8 25348397 N/A physical interaction ComPPI
PGRMC1 ATL3 25348397 N/A physical interaction ComPPI
PGRMC1 TCTN3 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PGRMC1 OTUB1 24234451 25348397 26752685 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PGRMC1 DUSP9 25348397 N/A physical interaction ComPPI
PGRMC1 B3GNT3 25348397 N/A physical interaction ComPPI
PGRMC1 CYP1A2 25348397 N/A physical interaction ComPPI
PGRMC1 HSD17B10 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PGRMC1 ATG5 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PGRMC1 MCC 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PGRMC1 NME2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PGRMC1 HLA-B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PGRMC1 ZNF71 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PGRMC1 PGRMC2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PGRMC1 KCNE5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PGRMC1 DEFB124 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PGRMC1 GOLM1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PGRMC1 PHOSPHO1 24234451 25348397 28330616 association pull down ComPPI,IntAct
PGRMC1 LAMP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
PLGRKT PGRMC1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
PAM16 PGRMC1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PCSK9 PGRMC1 25348397 N/A physical interaction ComPPI
DUSP21 PGRMC1 25348397 N/A physical interaction ComPPI
STK38L PGRMC1 24234451 30108113 association pull down,proximity-dependent biotin identification IntAct
PGRMC1 DIAPH3 24234451 30021884 physical association cross-linking study IntAct
PGRMC1 ZNF432 24234451 30021884 physical association cross-linking study IntAct
PGRMC1 DHCR24 24234451 30021884 physical association cross-linking study IntAct
PGRMC1 PBX4 24234451 30021884 physical association cross-linking study IntAct

Visualization










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