Gene Information gene info

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GENE：EML4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EML4
FullNmae EMAP like 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1316
EnsembleID ENSG00000143924
Uniprot Q9HC35

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EML4 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
EML4 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
EML4 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
EML4 GO:0000226,GO:0000278,GO:0003674,GO:0005515,GO:0005737,GO:0005737,GO:0005815,GO:0005829,GO:0005829,GO:0005874,GO:0007017,GO:0007080,GO:0008017,GO:0008608,GO:0015630,GO:0016020,GO:0030496,GO:0043014,GO:0043621,GO:0048487,GO:0051301,GO:0072686

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
EML4 hsa:27436 path:hsa05200 Pathways in cancer - Homo sapiens (human)
EML4 hsa:27436 path:hsa05223 Non-small cell lung cancer - Homo sapiens (human)
EML4 hsa:27436 path:hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR EML4 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 EML4 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 EML4 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 EML4 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 EML4 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 EML4 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 EML4 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 EML4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA EML4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF EML4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 EML4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 EML4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS EML4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A EML4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF EML4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 EML4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002152A8 EML4 20371350 21572407 23592263 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS0000070B1D EML4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000013DD8 EML4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000521626 EML4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000049FAE8 EML4 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000008C563 EML4 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 EML4 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001C04A2 EML4 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000065D58 EML4 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F EML4 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001DE669 EML4 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002C28B2 EML4 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000016E46F EML4 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA EML4 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C EML4 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001AFC71 EML4 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000028BB8 EML4 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000008F0CF EML4 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000080D0A EML4 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000058276F EML4 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000007F792 EML4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 EML4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 EML4 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TUBB EML4 25348397 N/A physical interaction ComPPI
SKP1 EML4 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
NTRK1 EML4 25348397 N/A physical interaction ComPPI
ILK EML4 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DCTN1 EML4 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PRPS1 EML4 25348397 N/A physical interaction ComPPI
TFEB EML4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ELAVL1 EML4 25348397 N/A physical interaction ComPPI
ARL4D EML4 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
NUDC EML4 25348397 N/A physical interaction ComPPI
NEK6 EML4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
FBXW11 EML4 25348397 N/A physical interaction ComPPI
NEK7 EML4 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
ARIH2 EML4 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
TUBB3 EML4 25348397 N/A physical interaction ComPPI
TKT EML4 25348397 N/A physical interaction ComPPI
EML4 TUBB2A 25348397 N/A physical interaction ComPPI
EML4 TUBB2B 25348397 N/A physical interaction ComPPI
EML4 PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct

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