GENE：LIPA
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | LIPA |
| FullNmae | lipase A, lysosomal acid type |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:6617 |
| EnsembleID | ENSG00000107798 |
| Uniprot | P38571 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| LIPA | lysosomal_cd | 36341760 | 220 lysosome-dependent cell death genes. | retulator signature |
| LIPA | lysosomal_cd | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
| LIPA | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| LIPA | GO:0000278,GO:0000902,GO:0001650,GO:0001935,GO:0002021,GO:0002244,GO:0002526,GO:0002536,GO:0004771,GO:0004771,GO:0004771,GO:0004771,GO:0005654,GO:0005764,GO:0005829,GO:0006006,GO:0006096,GO:0006631,GO:0006641,GO:0006695,GO:0006754,GO:0006776,GO:0006897,GO:0007005,GO:0007040,GO:0007264,GO:0008333,GO:0008340,GO:0009409,GO:0009410,GO:0010467,GO:0010878,GO:0016042,GO:0016125,GO:0016298,GO:0030099,GO:0030217,GO:0030324,GO:0030421,GO:0031929,GO:0033028,GO:0033189,GO:0033344,GO:0034383,GO:0035726,GO:0042098,GO:0042159,GO:0043202,GO:0043231,GO:0043231,GO:0048536,GO:0048539,GO:0048771,GO:0048873,GO:0050862,GO:0051881,GO:0055088,GO:0060612,GO:0060837,GO:0061519,GO:0070231,GO:0070341,GO:0071830,GO:0071838,GO:0072576,GO:0097384,GO:0140354,GO:0140962,GO:1901355,GO:1903409,GO:1990845 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| LIPA | hsa:3988 | path:hsa00100 | Steroid biosynthesis - Homo sapiens (human) |
| LIPA | hsa:3988 | path:hsa04142 | Lysosome - Homo sapiens (human) |
| LIPA | hsa:3988 | path:hsa04148 | Efferocytosis - Homo sapiens (human) |
| LIPA | hsa:3988 | path:hsa04979 | Cholesterol metabolism - Homo sapiens (human) |