Gene Information gene info

GENE:MRTFA

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MRTFA
FullNmae myocardin related transcription factor A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:14334
EnsembleID ENSG00000196588
Uniprot Q969V6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MRTFA autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MRTFA GO:0003713,GO:0003713,GO:0003713,GO:0003779,GO:0003785,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0005829,GO:0005829,GO:0030036,GO:0043522,GO:0044319,GO:0045944,GO:0045944,GO:0051145,GO:0051145,GO:1902895

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MRTFA RELA 14527995 23180781 physical association anti tag coimmunoprecipitation InnateDB
MRTFA EGR1 19374776 23180781 physical association anti tag coimmunoprecipitation InnateDB
MRTFA CREB1 18160048 23180781 physical association anti tag coimmunoprecipitation InnateDB
MRTFA LYL1 18160048 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR MRTFA 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 MRTFA 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 MRTFA 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 MRTFA 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 MRTFA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MRTFA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MRTFA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MRTFA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MRTFA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MRTFA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MRTFA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 MRTFA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MRTFA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MRTFA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MRTFA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 MRTFA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR MRTFA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 MRTFA 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000345DEB MRTFA 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
MAPKAPK2 MRTFA 22135298 phosphorylation N/A PhosphoSite
MAPK3 MRTFA 22135298 phosphorylation N/A PhosphoSite
MAPK14 MRTFA 22135298 phosphorylation N/A PhosphoSite
CDK2 MRTFA 22135298 phosphorylation N/A PhosphoSite
MAPK1 MRTFA 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
UBE2I MRTFA 14525934 16098147 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
KPNA3 MRTFA 20818336 24234451 25348397 physical association peptide array ComPPI,IntAct
CEP19 MRTFA 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
LCA5 MRTFA 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ACTB MRTFA 25348397 N/A physical interaction ComPPI
SUMO1 MRTFA 14525934 16098147 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
NCOA3 MRTFA 25348397 N/A physical interaction ComPPI
EP300 MRTFA 25348397 N/A physical interaction ComPPI
SMAD3 MRTFA 25348397 N/A physical interaction ComPPI
SRF MRTFA 12397177 14525934 14565952 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
GSK3B MRTFA 25348397 N/A physical interaction ComPPI
MVP MRTFA 25348397 N/A physical interaction ComPPI
SMARCA4 MRTFA 25348397 N/A physical interaction ComPPI
MYC MRTFA 21150319 24234451 25348397 association tandem affinity purification ComPPI,IntAct
XPO1 MRTFA 25348397 N/A physical interaction ComPPI
SUPT16H MRTFA 25348397 N/A physical interaction ComPPI
TRIM25 MRTFA 25348397 N/A physical interaction ComPPI
SSRP1 MRTFA 25348397 N/A physical interaction ComPPI
MYOCD MRTFA 14525934 14970199 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
MRTFA MRTFB 14525934 14565952 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
MRTFA KDM3A 25348397 N/A physical interaction ComPPI
MRTFA NXF1 25348397 N/A physical interaction ComPPI
MRTFA KIAA0753 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MRTFA CEP63 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MRTFA RPGRIP1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MRTFA TCTN1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MRTFA DNMT1 25348397 N/A physical interaction ComPPI
MRTFA BCL7A 25348397 N/A physical interaction ComPPI
MRTFA MRTFA 14525934 14565952 N/A experimental interaction detection HPRD
FUNDC2 MRTFA 24234451 30021884 physical association cross-linking study IntAct
MAPK3 MRTFA 18694962 22139079 27898060 inhibition N/A OmniPath
MAPK1 MRTFA 18694962 22139079 27898060 inhibition N/A OmniPath
MRTFA SRF 12397177 14565952 15610731 17599918 21673106 21965288 27898060 stimulant N/A OmniPath

Visualization