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GENE：NFIX

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NFIX
FullNmae nuclear factor I X
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7788
EnsembleID ENSG00000008441
Uniprot Q14938

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NFIX autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NFIX GO:0000122,GO:0000785,GO:0000978,GO:0000981,GO:0000981,GO:0003700,GO:0005515,GO:0005634,GO:0006260,GO:0006357,GO:0006366,GO:0045944,GO:1990837

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
NFIX PRDM1 20421211 23180781 physical association anti tag coimmunoprecipitation InnateDB
NFIX IRF1 20421211 23180781 physical association anti tag coimmunoprecipitation InnateDB
NFIX EGR1 19032775 23180781 physical association anti tag coimmunoprecipitation InnateDB
NFIX GUCY1B1 14504408 23180781 physical association affinity chromatography technology InnateDB
ISG15 NFIX 16009940 23180781 physical association unspecified method InnateDB

Source Target Pmid Interactiontype Methods Database
AR NFIX 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA2 NFIX 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
HIF1A NFIX 18971253 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
YBX1 NFIX 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 NFIX 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 NFIX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA NFIX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NFIX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 NFIX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NFIX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NFIX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 NFIX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS NFIX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A NFIX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF NFIX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR NFIX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 NFIX 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000B7E30 NFIX 19850724 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00000B7E30 NFIX 19850724 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS000005481D NFIX 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C770D NFIX 20371350 23592263 23622248 25416803 mrna cleavage,inhibition clip,clash TarBase
URS00004AE8D3 NFIX 20371350 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000235862 NFIX 20371350 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002E728C NFIX 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001DABC0 NFIX 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000B989F NFIX 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005FDE70 NFIX 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000419B5A NFIX 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000060AABB NFIX 20371350 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005F1B8C NFIX 20371350 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001AFC71 NFIX 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002578DA NFIX 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000024A59E NFIX 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002A79D1 NFIX 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000EC1BE NFIX 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000077DDE NFIX 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000C403E NFIX 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001ADE63 NFIX 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000BE495 NFIX 20371350 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000009EA8F NFIX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000023BE29 NFIX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002D0FC3 NFIX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000FFC8B NFIX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000C85B2 NFIX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002F72ED NFIX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000045ED38 NFIX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000027F5F3 NFIX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004E02F2 NFIX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000BD6DC NFIX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000047A8F NFIX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000003575B NFIX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001F373E NFIX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000ECE9C NFIX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000214763 NFIX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000076E54 NFIX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000001A7A NFIX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075BDA4 NFIX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002B0B46 NFIX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000157F5 NFIX 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000029979D NFIX 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000048B5E9 NFIX 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000338542 NFIX 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001C3AC1 NFIX 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00004AD450 NFIX 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000585553 NFIX 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003D5391 NFIX 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000036AFF1 NFIX 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
QRICH1 NFIX 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ISG15 NFIX 25348397 N/A physical interaction ComPPI
SMAD4 NFIX 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
JUN NFIX 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
RB1 NFIX 25348397 N/A physical interaction ComPPI
PIR NFIX 14525934 25348397 27898060 9079676 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,OmniPath
RFX1 NFIX 12624117 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
HNRNPL NFIX 25348397 N/A physical interaction ComPPI
FOXA1 NFIX 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
NFIB NFIX 14525934 25348397 9099724 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
TRIM25 NFIX 25348397 N/A physical interaction ComPPI
SKI NFIX 14525934 25348397 27898060 9380514 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
NFIX HDAC1 25348397 N/A physical interaction ComPPI
NFIX JMJD6 23455924 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NFIX ZNF614 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NFIX CREB1 24234451 25348397 25609649 physical association physical interaction,tandem affinity purification ComPPI,IntAct
NFIX FOS 25348397 N/A physical interaction ComPPI
NFIX RBPJ 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
NFIX FOXC1 25348397 N/A physical interaction ComPPI
NFIX FOXN1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
NFIX NFIX 12624117 14525934 24234451 25416956 physical association experimental interaction detection,two hybrid array HPRD,IntAct
ISG15 NFIX 16009940 27898060 N/A N/A OmniPath
FOXA1 NFIX 24801505 27898060 stimulant N/A OmniPath
NFIB NFIX 27898060 9099724 inhibition N/A OmniPath

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