GENE:RND3
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | RND3 |
FullNmae | Rho family GTPase 3 |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:671 |
EnsembleID | ENSG00000115963 |
Uniprot | P61587 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
RND3 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
RND3 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
RND3 | GO:0000139,GO:0003924,GO:0005515,GO:0005525,GO:0005829,GO:0005886,GO:0005886,GO:0005925,GO:0007015,GO:0007155,GO:0007165,GO:0007264,GO:0016477,GO:0019901,GO:0030036 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
AR | RND3 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
ESR1 | RND3 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
GATA3 | RND3 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
FOXA1 | RND3 | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
CEBPA | RND3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | RND3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F1 | RND3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | RND3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXP1 | RND3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | RND3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
GATA2 | RND3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | RND3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
MITF | RND3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
RUNX1 | RND3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TRIM28 | RND3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TP53 | RND3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TLE5 | RND3 | 23546594 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXD3 | RND3 | 21478267 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS00002075FA | RND3 | 22132820 | rna interference,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | miRSponge |
URS000012A1DD | RND3 | 20683643 | rna interference,inhibition | miRNA interference luciferase reporter assay | miRSponge |
URS000012A1DD | RND3 | 20683643 24151081 24667864 25416803 26254780 26935796 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
URS00002075FA | RND3 | 22132820 25416803 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
URS00004505E4 | RND3 | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
URS0000122ED0 | RND3 | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00000DDD35 | RND3 | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
URS0000065D58 | RND3 | 18668040 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
URS0000171525 | RND3 | 23821457 25416803 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
URS000039E1E1 | RND3 | 25416803 25950430 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
CPLANE2 | RND3 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
ROCK1 | RND3 | 12773565 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD |
ARHGAP5 | RND3 | 12842009 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD |
MAML1 | RND3 | 25348397 | N/A | physical interaction | ComPPI |
FBXW7 | RND3 | 25348397 | N/A | physical interaction | ComPPI |
NOTCH1 | RND3 | 25348397 | N/A | physical interaction | ComPPI |
UBXN11 | RND3 | 11940653 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid | ComPPI,HPRD |
CIT | RND3 | 25348397 | N/A | physical interaction | ComPPI |
YWHAB | RND3 | 23622247 24234451 25348397 | N/A | pull down | ComPPI,IntAct |
YWHAZ | RND3 | 23622247 24234451 25348397 | N/A | isothermal titration calorimetry,pull down,surface plasmon resonance,x-ray crystallography | ComPPI,IntAct |
RGS14 | RND3 | 25348397 | N/A | physical interaction | ComPPI |
SFN | RND3 | 15778465 24234451 25348397 | physical association | physical interaction,tandem affinity purification | ComPPI,IntAct |
SKP2 | RND3 | 24045951 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
ARHGAP35 | RND3 | 25348397 | N/A | physical interaction | ComPPI |
PLXNB1 | RND3 | 14732713 24234451 25348397 | physical association | affinity chromatography technology,physical interaction,affinity technology | ComPPI,IntAct |
RND3 | PLEKHG5 | 25348397 | N/A | physical interaction | ComPPI |
RND3 | RBPJ | 25348397 | N/A | physical interaction | ComPPI |
RND3 | C14ORF119 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
ROCK1 | RND3 | 12773565 15775972 27898060 | stimulant | N/A | OmniPath |
PRKCZ | RND3 | 23622247 27898060 | N/A | N/A | OmniPath |