GENE：ATP1B2
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | ATP1B2 |
| FullNmae | ATPase Na+/K+ transporting subunit beta 2 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:805 |
| EnsembleID | ENSG00000129244 |
| Uniprot | P14415 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| ATP1B2 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| ATP1B2 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| ATP1B2 | GO:0001671,GO:0001671,GO:0001895,GO:0001917,GO:0005515,GO:0005737,GO:0005886,GO:0005886,GO:0005890,GO:0005890,GO:0005890,GO:0006883,GO:0006883,GO:0009897,GO:0010976,GO:0016020,GO:0016324,GO:0016328,GO:0021670,GO:0021678,GO:0021944,GO:0030007,GO:0030007,GO:0030674,GO:0031253,GO:0031589,GO:0032781,GO:0036376,GO:0036376,GO:0044298,GO:0045494,GO:0046982,GO:0050821,GO:0051117,GO:0061744,GO:0071944,GO:0086009,GO:0086064,GO:0097449,GO:0097449,GO:0097450,GO:0098984,GO:0120036,GO:0150104,GO:1901018,GO:1903278,GO:1903288,GO:1903976,GO:1990573,GO:1990573 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| ATP1B2 | hsa:482 | path:hsa04022 | cGMP-PKG signaling pathway - Homo sapiens (human) |
| ATP1B2 | hsa:482 | path:hsa04024 | cAMP signaling pathway - Homo sapiens (human) |
| ATP1B2 | hsa:482 | path:hsa04260 | Cardiac muscle contraction - Homo sapiens (human) |
| ATP1B2 | hsa:482 | path:hsa04261 | Adrenergic signaling in cardiomyocytes - Homo sapiens (human) |
| ATP1B2 | hsa:482 | path:hsa04911 | Insulin secretion - Homo sapiens (human) |
| ATP1B2 | hsa:482 | path:hsa04918 | Thyroid hormone synthesis - Homo sapiens (human) |
| ATP1B2 | hsa:482 | path:hsa04919 | Thyroid hormone signaling pathway - Homo sapiens (human) |
| ATP1B2 | hsa:482 | path:hsa04925 | Aldosterone synthesis and secretion - Homo sapiens (human) |
| ATP1B2 | hsa:482 | path:hsa04960 | Aldosterone-regulated sodium reabsorption - Homo sapiens (human) |
| ATP1B2 | hsa:482 | path:hsa04961 | Endocrine and other factor-regulated calcium reabsorption - Homo sapiens (human) |
| ATP1B2 | hsa:482 | path:hsa04964 | Proximal tubule bicarbonate reclamation - Homo sapiens (human) |
| ATP1B2 | hsa:482 | path:hsa04970 | Salivary secretion - Homo sapiens (human) |
| ATP1B2 | hsa:482 | path:hsa04971 | Gastric acid secretion - Homo sapiens (human) |
| ATP1B2 | hsa:482 | path:hsa04972 | Pancreatic secretion - Homo sapiens (human) |
| ATP1B2 | hsa:482 | path:hsa04973 | Carbohydrate digestion and absorption - Homo sapiens (human) |
| ATP1B2 | hsa:482 | path:hsa04974 | Protein digestion and absorption - Homo sapiens (human) |
| ATP1B2 | hsa:482 | path:hsa04976 | Bile secretion - Homo sapiens (human) |
| ATP1B2 | hsa:482 | path:hsa04978 | Mineral absorption - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| GATA2 | ATP1B2 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| YBX1 | ATP1B2 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| PRDM14 | ATP1B2 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| CEBPA | ATP1B2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | ATP1B2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | ATP1B2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| NGB | ATP1B2 | 12958655 14525934 25348397 27898060 | N/A | two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid | ComPPI,HPRD,OmniPath |
| RPS18 | ATP1B2 | 25348397 | N/A | physical interaction | ComPPI |
| RPLP2 | ATP1B2 | 25348397 | N/A | physical interaction | ComPPI |
| ATP1A1 | ATP1B2 | 25348397 | N/A | physical interaction | ComPPI |
| ATP1B2 | COPG2 | 25348397 | N/A | physical interaction | ComPPI |
| ATP1B2 | ATP5PB | 25348397 | N/A | physical interaction | ComPPI |
| ATP1B2 | RPL26 | 25348397 | N/A | physical interaction | ComPPI |
| ATP1B2 | RPS8 | 25348397 | N/A | physical interaction | ComPPI |
| ATP1B2 | RTN4 | 25348397 | N/A | physical interaction | ComPPI |
| ATP1B2 | TARDBP | 25348397 | N/A | physical interaction | ComPPI |
| ATP1B2 | RS1 | 17804407 24234451 25348397 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |