Gene Information gene info

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GENE：CAV2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CAV2
FullNmae caveolin 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1528
EnsembleID ENSG00000105971
Uniprot P51636

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CAV2 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CAV2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CAV2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CAV2 GO:0000139,GO:0001935,GO:0001937,GO:0001937,GO:0001938,GO:0002080,GO:0002095,GO:0005515,GO:0005634,GO:0005794,GO:0005794,GO:0005886,GO:0005901,GO:0005925,GO:0005925,GO:0006906,GO:0007005,GO:0007029,GO:0007088,GO:0007179,GO:0008286,GO:0008286,GO:0014856,GO:0014859,GO:0016050,GO:0019065,GO:0019076,GO:0019901,GO:0030133,GO:0030154,GO:0030512,GO:0030674,GO:0031410,GO:0031410,GO:0032991,GO:0042383,GO:0042803,GO:0043410,GO:0043410,GO:0043547,GO:0044794,GO:0044853,GO:0045121,GO:0046982,GO:0048278,GO:0048471,GO:0048471,GO:0048741,GO:0051480,GO:0060090,GO:0060161,GO:0070836,GO:0070836,GO:0070836,GO:0071711,GO:0097110

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CAV2 hsa:858 path:hsa04144 Endocytosis - Homo sapiens (human)
CAV2 hsa:858 path:hsa04510 Focal adhesion - Homo sapiens (human)
CAV2 hsa:858 path:hsa05020 Prion disease - Homo sapiens (human)
CAV2 hsa:858 path:hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human)
CAV2 hsa:858 path:hsa05205 Proteoglycans in cancer - Homo sapiens (human)
CAV2 hsa:858 path:hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EGFR CAV2 16799092 23180781 physical association pull down InnateDB
RASA1 CAV2 12091389 15504032 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
CAV2 PLD2 20005715 interaction type N/A PSP
CAV2 SRC 20005715 interaction type N/A PSP
CAV2 SRC 20005715 N/A N/A SignaLink
CAV2 PLD2 10675563 20005715 20005715 21071413 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR CAV2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 CAV2 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
GATA1 CAV2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 CAV2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 CAV2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CAV2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 CAV2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CAV2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CAV2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CAV2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF CAV2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 CAV2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 CAV2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 CAV2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000DDD35 CAV2 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS000003ABC4 CAV2 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00003E2232 CAV2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000031B6ED CAV2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004CCA62 CAV2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000023F8DA CAV2 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CSNK2A1 CAV2 22135298 phosphorylation N/A PhosphoSite
SRC CAV2 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
CAV2 PLD2 25361965 interaction type N/A PTMCode2
PLD2 CAV2 25361965 interaction type N/A PTMCode2
CAV2 CAV1 25361965 interaction type N/A PTMCode2
CAV1 CAV2 25361965 interaction type N/A PTMCode2
CAV2 SRC 25361965 interaction type N/A PTMCode2
CAV2 FLOT2 25361965 interaction type N/A PTMCode2
FLOT2 CAV2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
MALL CAV2 11294831 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
SRC CAV2 12091389 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
NCK1 CAV2 12091389 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PLD2 CAV2 25348397 N/A physical interaction ComPPI
CAV1 CAV2 10212252 12414992 14525934 18081315 24013648 24234451 25348397 27898060 9361015 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct,OmniPath
CSNK2A1 CAV2 25348397 N/A physical interaction ComPPI
SDCBP CAV2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EGFR CAV2 14525934 16799092 24234451 24658140 25348397 association,physical association anti bait coimmunoprecipitation,experimental interaction detection,ubiquitin reconstruction,physical interaction,in vivo ComPPI,HPRD,IntAct
RASA1 CAV2 14525934 15504032 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
ANXA2 CAV2 22301157 24234451 25348397 colocalization confocal microscopy ComPPI,IntAct
CAV2 DRD1 14525934 15569306 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
CAV2 GOLGB1 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CAV2 FLOT2 10212252 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CAV2 DNAJA1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CAV2 KCNMA1 25348397 N/A physical interaction ComPPI
CAV2 PTGS1 25348397 N/A physical interaction ComPPI
SRC CAV2 12091389 12743374 15504032 17081983 18669648 20068231 20455999 27898060 inhibition,stimulant N/A OmniPath
EGFR CAV2 16799092 24658140 25402006 27898060 N/A N/A OmniPath
CSNK2A1 CAV2 12743374 16527823 18081315 22819829 27898060 stimulant N/A OmniPath
RASA1 CAV2 12091389 1550403 15504032 27898060 stimulant N/A OmniPath
SYK CAV2 12743374 15504032 27898060 N/A N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00008B5630 CAV2 27087310 direct interaction,inhibition N/A NPInter

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