Gene Information gene info

GENE:CDKL3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CDKL3
FullNmae cyclin dependent kinase like 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:15483
EnsembleID ENSG00000006837
Uniprot Q8IVW4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CDKL3 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CDKL3 GO:0004672,GO:0004674,GO:0004693,GO:0005515,GO:0005524,GO:0005634,GO:0005737,GO:0006468,GO:0016310,GO:0030517,GO:0036211,GO:0050775,GO:0051726,GO:0097484,GO:0106310

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
APP CDKL3 21832049 23180781 physical association protein array InnateDB
SRPK1 CDKL3 23180781 23602568 phosphorylation reaction protein kinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 CDKL3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TFAP2C CDKL3 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 CDKL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CDKL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CDKL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 CDKL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 CDKL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CDKL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CDKL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 CDKL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CDKL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CDKL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF CDKL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 CDKL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
GOLGA2 CDKL3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ZBTB8A CDKL3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HSPA8 CDKL3 25348397 N/A physical interaction ComPPI
FXR2 CDKL3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ZBTB43 CDKL3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ZBTB14 CDKL3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
LZTS2 CDKL3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CDK6 CDKL3 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
KASH5 CDKL3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MDFI CDKL3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PICK1 CDKL3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SNRNP70 CDKL3 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TTF2 CDKL3 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RABEP1 CDKL3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SRPK1 CDKL3 23602568 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
GGA1 CDKL3 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
LRP2BP CDKL3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRIM27 CDKL3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
STAMBP CDKL3 25348397 N/A physical interaction ComPPI
TRIM37 CDKL3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ZRANB1 CDKL3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATG4A CDKL3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MCC CDKL3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MTUS2 CDKL3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
APP CDKL3 25348397 N/A physical interaction ComPPI
LRRK2 CDKL3 24234451 25348397 29513927 N/A protein array ComPPI,IntAct
CYSRT1 CDKL3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KANK2 CDKL3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CDKL3 KRTAP10-9 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CDKL3 PIH1D2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DNAAF6 CDKL3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct

Visualization